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公开(公告)号:US10544218B2
公开(公告)日:2020-01-28
申请号:US15349964
申请日:2016-11-11
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K38/05 , A61K31/537 , C07K16/30 , A61K51/10 , G01N33/574 , A61K45/06 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20190276550A9
公开(公告)日:2019-09-12
申请号:US13973669
申请日:2013-08-22
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20190248903A1
公开(公告)日:2019-08-15
申请号:US16250398
申请日:2019-01-17
Applicant: Genentech, Inc.
Inventor: Bing ZHENG , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K31/5517 , A61K47/68 , A61K51/10 , A61K31/706 , C07K16/30 , G01N33/574
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10150813B2
公开(公告)日:2018-12-11
申请号:US14773334
申请日:2014-03-13
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K39/395 , A61K38/08 , A61K51/10 , C07K16/30 , G01N33/569 , A61K47/65 , A61K47/68 , A61K39/00
Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20180169259A1
公开(公告)日:2018-06-21
申请号:US15628813
申请日:2017-06-21
Applicant: Genentech Inc.
Inventor: Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu
IPC: A61K47/68 , A61K45/06 , A61K31/551
CPC classification number: A61K47/6813 , A61K31/551 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867 , A61K2300/00
Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20180009894A1
公开(公告)日:2018-01-11
申请号:US15657472
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K31/706 , A61K51/10 , G01N33/574 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US09562099B2
公开(公告)日:2017-02-07
申请号:US14207878
申请日:2014-03-13
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/48 , A61K45/06 , G01N33/574 , A61K51/10 , A61K39/395 , A61K39/00
CPC classification number: C07K16/3015 , A61K31/5377 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2827 , C07K16/3069 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/567 , C07K2317/77 , C07K2317/92 , G01N33/57492 , A61K2300/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20170002074A1
公开(公告)日:2017-01-05
申请号:US15171128
申请日:2016-06-02
Applicant: GENENTECH, INC.
Inventor: Shang-Fan Yu , Wei-Ching Liang , Yan Wu , Steven Leong , Andrew Polson
IPC: C07K16/28 , G01N33/574 , A61K47/48
CPC classification number: C07K16/2803 , A61K47/6809 , A61K47/6849 , A61K2039/505 , C07K2317/33 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492 , G01N2333/70596 , G01N2458/00
Abstract: The invention provides anti-CD33 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD33抗体和免疫缀合物及其使用方法。
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9.ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS 审中-公开
Title translation: 蒽醌衍生物偶联物,其制备方法及其作为抗微生物化合物的用途公开(公告)号:US20150051380A1
公开(公告)日:2015-02-19
申请号:US14528142
申请日:2014-10-30
Applicant: Genentech, Inc.
Inventor: Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
CPC classification number: C07K16/2863 , A61K47/64 , A61K47/6809 , C07K2317/76
Abstract: The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
Abstract translation: 本发明涉及治疗有用的蒽环类与载体的缀合物,例如天然或合成来源的多克隆和单克隆抗体,蛋白质或肽; 其制备方法,含有它们的药物组合物及其在治疗某些哺乳动物肿瘤中的用途。
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10.ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE 审中-公开
Title translation: 抗CD79B抗体和免疫球蛋白及其使用方法公开(公告)号:US20140335107A1
公开(公告)日:2014-11-13
申请号:US14219473
申请日:2014-03-19
Applicant: GENENTECH, INC.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson
IPC: C07K16/28 , G01N33/574
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物,以及使用这些物质组合物的方法。
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