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公开(公告)号：US20230176045A1
公开(公告)日：2023-06-08
申请号：US17928663
申请日：2021-05-12
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
IPC: G01N33/543 , G01N21/64 , B01L3/00
CPC classification number: G01N33/54386 , G01N21/6458 , G01N21/6428 , B01L3/502761 , G01N2021/6439 , B01L2400/084 , B01L2300/0654 , B01L2200/0647 , B01L2200/16
Abstract: The present disclosure provides microfluidic flow channel structure, detection system and method for using detection system, aiming at improving uniformity of liquid introduction of microfluidic detection system. Microfluidic flow channel structure includes liquid inlet section (1), main chamber (3) and liquid outlet section (2), main chamber (3) includes liquid inlet end (31), chamber middle part (33) and liquid outlet end (32); liquid inlet section (1), liquid inlet end (31), chamber middle part (33), liquid outlet end (32) and liquid outlet section (2) are sequentially connected together; width of liquid inlet end (31) is gradually increased in direction from liquid inlet section (1) to chamber middle part (33); thinning flow guidance region (310) is provided at edge of liquid inlet end (31) formed as width of liquid inlet end varies, and has thickness less than that of remaining region except thinning flow guidance region (310) of main chamber (3).
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公开(公告)号：US20220274106A1
公开(公告)日：2022-09-01
申请号：US17631461
申请日：2021-03-03
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. A surface activation treatment is performed on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; and a solution containing an oxy compound is then used to perform a surface epoxidation treatment on the hydrophilic layer in order to form an epoxy-containing modification group on the surface of the hydrophilic layer.
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公开(公告)号：US20240183848A1
公开(公告)日：2024-06-06
申请号：US17778177
申请日：2021-06-08
Inventor： Haonan LIU , Ding DING
IPC: G01N33/543 , B01L3/00
CPC classification number: G01N33/54386 , B01L3/502761 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , G01N2470/04
Abstract: The present application discloses a first substrate for a microfluidic chip, the microfluidic chip, and a method for processing a sample. The first substrate includes a first injection port, a first reacting region, a first upstream end of which is communicated with the first injection port, a second injection port, a second reacting region, an upstream end of which is communicated with the second injection port, and a downstream end of which is communicated with a second upstream end of the first reacting region, a fluid backflow prevention region between the second reacting region and the first reacting region, an upstream end of which is communicated with the downstream end of the second reacting region, and a downstream end of which is communicated with the second upstream end of the first reacting region, and an exit port communicated with a downstream end of the first reacting region.
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4.发明公开公开(公告)号：US20240035802A1
公开(公告)日：2024-02-01
申请号：US17639032
申请日：2021-04-29
Inventor： Xiangguo MA , Haonan LIU , Kai GENG , Shinying LAU
IPC: G01B9/02
CPC classification number: G01B9/02051 , G01N2035/0405
Abstract: A cabin entry-and-exit structure, an analysis device and an analysis system are provided. The cabin entry-and-exit structure includes a carrier body, a guide support assembly and a door opening-and-closing assembly. The carrier body is configured to bear the loading part; the guide support assembly is disposed on a base board in a cabin body of the analysis device, is configured to support the carrier body, and is movably connected to the carrier body so that the carrier body is movable; the door opening-and-closing assembly is disposed on the base board and located on a side of the carrier body far away from a door, configured to apply a pushing force to the carrier body towards the exit direction when the carrier body is subjected to a pressing force and to lock the carrier body at a cabin closing position when the carrier body is subjected to a pressing force again.
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公开(公告)号：US20220274107A1
公开(公告)日：2022-09-01
申请号：US17631463
申请日：2021-03-04
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The method for modifying the detection chip comprises performing a surface film-forming treatment on a hydrophilic layer on a first substrate constituting the detection chip to form polydopamine film on a surface of the hydrophilic layer; and adopting a buffer solution containing sodium hyaluronate to perform a surface carboxylation treatment on the hydrophilic layer, on the surface of which the polydopamine film has been formed, in order to form a carboxyl-containing modification group on the surface of the hydrophilic layer.
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Patent Agency Ranking
公开(公告)号：US20220274105A1
公开(公告)日：2022-09-01
申请号：US17631460
申请日：2021-03-03
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The modification method includes performing a surface activation treatment on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; then performing a surface amination treatment on the hydrophilic layer using a solution containing an amino compound, such that an amino-containing modification group is formed on the surface of the hydrophilic layer, and performing a surface carboxylation treatment on the hydrophilic layer using a solution containing an anhydride compound, such that a carboxyl-containing modification group is formed on the surface of the hydrophilic layer.
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公开(公告)号：US20220163516A1
公开(公告)日：2022-05-26
申请号：US17355338
申请日：2021-06-23
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Haonan LIU , Yudan YIN , Ding DING
IPC: G01N33/543 , B01L3/00
Abstract: The present disclosure provides a digital immunochip and a manufacture method thereof. The digital immunochip includes a first substrate and a second substrate which are opposite to each other. The first substrate includes: a first base substrate; at least one driving electrode on the first base substrate and configured to drive an object to be detected to move; a dielectric layer on a side of the at least one driving electrode away from the first base substrate and covering the at least one driving electrode; and a first hydrophobic layer on a side of the dielectric layer away from the first base substrate. The second substrate includes: a second base substrate; and an immunoassay substance on a side of the second base substrate proximal to the first hydrophobic layer of the first substrate and including an antigen or an antibody.
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公开(公告)号：US20240036036A1
公开(公告)日：2024-02-01
申请号：US17639078
申请日：2021-04-29
Inventor： Haonan LIU , Xiangguo MA , Kai GENG , Ding DING
IPC: G01N33/543 , B01L3/00 , G01N35/10
CPC classification number: G01N33/54306 , G01N33/54386 , B01L3/502761 , G01N35/10 , B01L2200/16 , B01L2200/0647 , B01L2300/027 , B01L2300/0636
Abstract: An immunoassay device and an immunoassay method are provided. The immunoassay device includes: a housing, a driving assembly, a detection chip and a liquid storage chamber; the housing has a first accommodating part in which the detection chip is disposed and a second accommodating part in which the liquid storage chamber is disposed, and the liquid storage chamber is configured at least to store reagent; the driving assembly is configured to communicate a liquid outlet of the liquid storage chamber with a liquid inlet of the detection chip, and drive the reagent in the liquid storage chamber to enter the detection chip.
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公开(公告)号：US20230158508A1
公开(公告)日：2023-05-25
申请号：US17753101
申请日：2021-03-12
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Ruijun DENG , Zhukai LIU , Ding DING , Haonan LIU
CPC classification number: B01L7/52 , B01L3/502707 , B01L2300/12 , B01L2300/1827
Abstract: The present disclosure provides a microfluidic substrate, a microfluidic chip and a manufacturing method thereof. The microfluidic substrate includes: a first substrate; a conductive layer on the first substrate; and a defining layer on a side of the conductive layer facing away from the first substrate, the defining layer defining a concave portion; wherein the conductive layer comprises a plurality of conductive patterns corresponding to the concave portion, the plurality of conductive patterns are arranged along a first direction, each conductive pattern extends along a second direction and comprises a first end and a second end, the first direction is perpendicular to the second direction, and each conductive pattern has a maximum local resistance value at the first end and the second end of the conductive pattern.
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公开(公告)号：US20230137571A1
公开(公告)日：2023-05-04
申请号：US17606695
申请日：2021-02-05
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Haonan LIU , Yudan YIN , Ding DING
Abstract: The present disclosure relates to a microfluidic chip. The microfluidic chip includes a first substrate, and the first substrate includes a sample input hole and a reaction region located downstream of the sample input hole. The reaction region includes at least one groove, an orthographic projection of each groove on the first substrate is an axisymmetric pattern, a width of the axisymmetric pattern in a first direction is not less than a width of the axisymmetric pattern in a second direction, and the first direction is perpendicular to the second direction.
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