-
公开(公告)号：US20230158508A1
公开(公告)日：2023-05-25
申请号：US17753101
申请日：2021-03-12
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Ruijun DENG , Zhukai LIU , Ding DING , Haonan LIU
CPC classification number: B01L7/52 , B01L3/502707 , B01L2300/12 , B01L2300/1827
Abstract: The present disclosure provides a microfluidic substrate, a microfluidic chip and a manufacturing method thereof. The microfluidic substrate includes: a first substrate; a conductive layer on the first substrate; and a defining layer on a side of the conductive layer facing away from the first substrate, the defining layer defining a concave portion; wherein the conductive layer comprises a plurality of conductive patterns corresponding to the concave portion, the plurality of conductive patterns are arranged along a first direction, each conductive pattern extends along a second direction and comprises a first end and a second end, the first direction is perpendicular to the second direction, and each conductive pattern has a maximum local resistance value at the first end and the second end of the conductive pattern.
-
公开(公告)号：US20240165619A1
公开(公告)日：2024-05-23
申请号：US17772647
申请日：2021-05-31
Inventor： Zhukai LIU , Ding DING
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L2300/0874 , B01L2300/1883
Abstract: The present disclosure provide a detection chip having at least one functional region, the functional region including: a reaction region and a non-reaction region surrounding the reaction region. The detection chip includes: a first substrate and a second substrate opposite to each other. In the reaction region, a side of the first substrate facing the second substrate is provided with reaction grooves arranged in an array along a first direction and a second direction; first communication grooves each between two reaction grooves adjacent in the first direction, and connected with the two reaction grooves; and second communication grooves each between two first communication grooves adjacent in the second direction, and connected with the two adjacent first communication grooves, and the first direction intersects the second direction. The embodiments of the present disclosure further provide a fabrication method and a sample introduction method of the detection chip.
-
公开(公告)号：US20230230229A1
公开(公告)日：2023-07-20
申请号：US17927025
申请日：2021-02-23
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Qiong WU , Mengjun HOU , Xiangguo MA , Kai GENG , Zhukai LIU
CPC classification number: G06T7/0012 , G01N21/6456 , G06T3/40 , G06T5/002 , G06T5/20 , G06T5/50 , G06T7/11 , G06T7/80 , G06T2207/10064 , G06T2207/20061 , G06T2207/20224 , G06T2207/30072
Abstract: A method for analyzing a biochip image is provided, including: (S1) acquiring and preprocessing the biochip image to obtain a preprocessed image; (S2) performing a correction for angle deflection on the preprocessed image to obtain a deflection-corrected image; and (S3) performing an enhancement processing on the deflection-corrected image, and identifying a positive or negative of an area of interest in the preprocessed image according to an image on which the enhancement processing has been performed. An apparatus (100) for analyzing a biochip image, a method for analyzing an image, a computer device (200) and a storage medium are disclosed.
-
公开(公告)号：US20240351026A1
公开(公告)日：2024-10-24
申请号：US18039220
申请日：2022-03-25
Inventor： Xiangguo MA , Zhukai LIU , Ding DING , Lin DENG
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/5025 , B01L2200/027 , B01L2300/0829
Abstract: A chip packaging structure and a chip packaging method, the structure including: a sample substrate with through holes; first and second cover plates on opposite sides of the sample substrate; and at least one pair of a sample inlet and a sample outlet, each pair of the sample inlet and the sample outlet is in one or both of the first cover plate and the second cover plate, a flow path is between each pair of the sample inlet and the sample outlet, a first flow channel structure is on a surface of the first cover plate opposite to the sample substrate, a second flow channel structure is on a surface of the second cover plate opposite to the sample substrate, and the first flow channel structure and the second flow channel structure are connected with the through holes, to form a continuous channel corresponding to the flow path.
-
公开(公告)号：US20220274107A1
公开(公告)日：2022-09-01
申请号：US17631463
申请日：2021-03-04
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The method for modifying the detection chip comprises performing a surface film-forming treatment on a hydrophilic layer on a first substrate constituting the detection chip to form polydopamine film on a surface of the hydrophilic layer; and adopting a buffer solution containing sodium hyaluronate to perform a surface carboxylation treatment on the hydrophilic layer, on the surface of which the polydopamine film has been formed, in order to form a carboxyl-containing modification group on the surface of the hydrophilic layer.
-
Patent Agency Ranking
公开(公告)号：US20220274105A1
公开(公告)日：2022-09-01
申请号：US17631460
申请日：2021-03-03
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The modification method includes performing a surface activation treatment on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; then performing a surface amination treatment on the hydrophilic layer using a solution containing an amino compound, such that an amino-containing modification group is formed on the surface of the hydrophilic layer, and performing a surface carboxylation treatment on the hydrophilic layer using a solution containing an anhydride compound, such that a carboxyl-containing modification group is formed on the surface of the hydrophilic layer.
-
7.发明公开公开(公告)号：US20240359174A1
公开(公告)日：2024-10-31
申请号：US18029792
申请日：2022-05-19
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Yunqing MU , Haonan LIU , Zhukai LIU , Ding DING
IPC: B01L3/00
CPC classification number: B01L3/502707 , B01L2200/025 , B01L2200/12 , B01L2200/16 , B01L2300/12 , B01L2300/161
Abstract: A gene detection substrate is provided, including: a substrate; a gene detection channel in the substrate, an opening of the gene detection channel is on one side of the substrate; the gene detection channel includes a sample injection groove, a sample outgoing groove and a flow channel groove sequentially connected and communicated with each other; the flow channel groove includes reaction holes and flow channel structures; the reaction holes are distributed at intervals, and any two adjacent reaction holes are communicated with each other through the flow channel structure; the flow channel structure includes a first, second, and third sub-grooves sequentially connected and communicated with each other; a width of each of the first and third sub-grooves in a first direction is smaller than that of the second sub-groove in the first direction; and the first direction is perpendicular to an arrangement direction of two adjacent reaction holes.
-
公开(公告)号：US20240299933A1
公开(公告)日：2024-09-12
申请号：US18024892
申请日：2022-03-15
Inventor： Kang PENG , Ding DING , Zhukai LIU
CPC classification number: B01L3/502715 , B01L2200/0647 , B01L2200/12 , B01L2300/04 , B01L2300/0645 , B01L2300/161 , B01L2400/06 , H01L27/1214
Abstract: Provided are a microfluidic chip and a usage method thereof, and a microfluidic system. The microfluidic chip includes a substrate layer, the substrate layer includes a substrate and a drive electrode layer; and a cover plate layer arranged opposite the substrate layer, a space between the cover plate layer and the substrate layer form a solution accommodating space; the cover plate layer includes a solution inlet hole, a solution outlet hole, and limiting recesses arranged on a side of the cover plate layer facing the substrate layer, the solution inlet hole, the solution outlet hole and each limiting recess are in communication with the solution accommodating space, and an end surface of the solution inlet hole adjacent to the substrate layer, an end surface of the solution outlet hole adjacent to the substrate layer, and opening surfaces of the plurality of limiting recesses are arranged substantially flush with one another.
-
公开(公告)号：US20240181443A1
公开(公告)日：2024-06-06
申请号：US17789263
申请日：2021-08-27
Inventor： Ruijun DENG , Zhukai LIU , Ding DING
IPC: B01L3/00 , B01L7/00 , C12Q1/6851
CPC classification number: B01L3/5023 , B01L3/502753 , B01L7/52 , C12Q1/6851 , B01L2200/16 , B01L2300/069 , B01L2300/0816 , B01L2300/161 , B01L2300/18
Abstract: A high-throughput test chip includes: a backplane, a cover plate and a connector. The backplane and the cover plate are aligned to form a plurality of accommodation chambers. Test chip units are disposed on one side of the backplane facing the cover plate, and each of the test chip units is located in the corresponding accommodation chamber. Each of the accommodation chambers is provided with a liquid inlet and a liquid outlet. The connector includes pipelines; each of the pipelines is provided with a valve structure configured to control connection or disconnection of the pipeline. In each pair of a pipeline and an accommodation chamber, an inlet of the pipeline communicates with the liquid outlet of the accommodation chamber; the pipelines form at least one pipeline group, each pipeline group at least includes two pipelines, and the pipelines in each pipeline group share the same sample liquid outlet.
-
公开(公告)号：US20250033056A1
公开(公告)日：2025-01-30
申请号：US18713233
申请日：2022-04-20
Inventor： Ding DING , Jian XU , Lin DENG , Zhukai LIU
IPC: B01L3/00
Abstract: A microwell array chip, a use method therefor, and a detection apparatus. The microwell array chip includes a microwell array substrate, and the microwell array substrate includes n reaction chambers, and an idle region; an array of the n reaction chambers is disposed in the microwell array substrate, and the idle region is disposed around the n reaction chambers; each reaction chamber is configured to accommodate a sample to be tested, and the shape of an orthographic projection of the reaction chamber on a first reference plane where the first main surface is located is of a regular N-gon; the area of the idle region is divided into n′ virtual units, and the shape of the orthographic projection of each virtual unit on the first reference plane is the same as the shape of the orthographic projection of the reaction chamber on the first reference plane.
-
-
-
-
-
-
-
-
-
Search Results
16
records
(took 0.027 seconds)
