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1.外观设计
公开(公告)号：USD306480S
公开(公告)日：1990-03-06
申请号：US4535
申请日：1987-01-15
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公开(公告)号：US4874582A
公开(公告)日：1989-10-17
申请号：US109584
申请日：1987-10-19
CPC分类号： G01N1/2813 , G01N2001/2846 , Y10T436/111666
摘要： A sample handling unit for centrifugation apparatus, especially for cytocentrifugation to produce cell monolayers is disclosed. The sample handling unit is adapted for automated protective processing, e.g. fixation, of matter deposited on a slide during the centrifugation operation. For this purpose the unit has a body defining a deposition chamber, and a treatment fluid reservoir communicating with the deposition chamber via a buffer chamber and a flow path including a weir so arranged that in the position for centrifugation, treatment fluid such as fixative placed in the reservoir is retained therein until centrifugation produces an artificial gravitational field that causes the fluid to flow to the buffer chamber in which it is then retained by the weir for so long as the artificial gravitational field is maintained. Upon decay of that field the fluid flows over the weir towards the deposition chamber. There may be a series of such reservoirs and associated buffer chambers and weirs in respective flow paths or in an extended flow path through which flow path or paths a succession of treatment fluids are caused to progress in sequence by repeatedly applying the artificial gravitational field. There may also be a sample reservoir that communicates with the deposition chamber in a manner providing for transfer of sample material from this reservoir to the deposition chamber only when the artificial gravitational field is applied.
摘要翻译： 公开了用于离心装置的样品处理单元，特别是用于细胞离心以产生细胞单层的样品处理单元。 样品处理单元适用于自动保护处理，例如， 在离心操作期间沉积在载玻片上的物质的固定。 为此，该单元具有限定沉积室的主体和经由缓冲室与沉积室连通的处理流体储存器和包括堰的流路，其布置成使得在用于离心的位置处理流体如固定剂置于 储存器被保留在其中，直到离心产生人造重力场，其导致流体流向缓冲室，然后在保持该人造重力场的状态下，流体被堰保持。 在该场的衰减时，流体流过沉积物室。 在相应的流动路径中或在延伸的流动路径中可以存在一系列这样的储存器和相关联的缓冲室和堰，在延伸的流动路径中，使得一系列处理流体的流动路径或路径通过反复施加人造引力场而顺序地进行。 也可以存在与沉积室连通的样品贮存器，其方式仅在施加人造重力场时提供将样品材料从该储存器转移到沉积室。
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公开(公告)号：US4834019A
公开(公告)日：1989-05-30
申请号：US125348
申请日：1987-11-25
CPC分类号： G01N1/312
摘要： Tissue specimen treatment apparatus of the multi-chamber type having a plurality of containers, for instance arranged in a circle, and means for transporting a specimen for treatment to selected such chambers in a prescribed sequence, is characterized by a containment vessel disposed about at least the open tops of the containers and by cover means movable with the transporting means and evelosing the interior of the containment vessel so as to separate the specimen from the ambient atmosphere. The cover means preferably closely overlies the open tops of the containers to minimize the volume of the containment vessel, and is formed with a small volume transfer enclosure to receive a specimen during transport. The cover may have a close fit to the containment vessel, sufficient to restrict exchange of gases etc. between the external atmosphere and the containment vessel, or more positive sealing arrangements may be provided--e.g. labyrinth, flexible or liquid seals--to prevent flows between the vessel and the environment. Additionally or alternatively, positive venting of the containment vessel by withdrawal of its atmosphere may ensure that all leakages are into the vessel.
摘要翻译： 具有多个容器的多室型组织样品处理装置，例如以圆形布置，以及用于以规定的顺序将待处理的样品输送到所选择的这些室的装置的特征在于至少设置有容纳容器 容器的开口顶部和通过运送装置移动的盖子装置，并且将密封容器的内部隔开，以将样品与环境大气分离。 盖装置优选地紧密地覆盖在容器的开口顶部以使容纳容器的体积最小化，并且形成有小体积传送外壳以在运输期间接收样品。 盖可以紧密地配合到容纳容器，足以限制外部大气和容纳容器之间的气体等的交换，或者可以提供更多的正密封装置。 迷宫式，柔性或液体密封，以防止船舶和环境之间的流动。 另外或者替代地，通过撤回其气氛来积极地排放容器，可以确保所有泄漏进入容器。
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公开(公告)号：US4391710A
公开(公告)日：1983-07-05
申请号：US289374
申请日：1981-08-03
申请人： Alan J. Gordon
发明人： Alan J. Gordon
CPC分类号： B04B5/0421 , G01N1/2813 , B04B2007/025 , G01N2001/2846
摘要： A cytocentrifuge especially suitable for centrifugation of materials requiring handling under conditions of containment is characterized by a plurality of holders each adapted to retain an individual sample chamber in juxtaposition to a receiving surface with interposed filter/seal and removable as a unit from the rotating carrier of the machine. The holder is preferably adapted to be supported tiltingly by the carrier so as only under centrifugal force to permit a sample to contact the receiving surface and while this is perpendicular to the centrifugal load on the sample. The carrier is preferably an apertured plate removable from a drive hub for cleansing and sterilization, and the drive hub forms part of a sealable head assembly of containment bowl and removable cover, the head assembly being removable as a unit for loading/unloading under containment conditions.
摘要翻译： 特别适用于需要在遏制条件下处理的材料的离心的细胞离心机的特征在于多个保持器，每个保持器适于将单独的样品室保持在与插入的过滤器/密封件相接合的接收表面上并作为一个单元从可旋转载体 机器。 保持器优选地适于由载体倾斜地支撑，以便仅在离心力下允许样品与接收表面接触并且同时其垂直于样品上的离心负载。 载体优选是可从驱动轮毂移除以用于清洁和灭菌的有孔板，并且驱动毂形成容纳碗和可移除盖的可密封头部组件的一部分，头部组件可移除作为在容纳条件下装载/卸载的单元 。
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公开(公告)号：US4171241A
公开(公告)日：1979-10-16
申请号：US883466
申请日：1978-03-06
CPC分类号： B65G59/067 , G02B21/34 , Y10T156/1744 , Y10T156/1783 , Y10T156/1798
摘要： A dispenser for thin flat rigid articles such as glass cover slips for microscope slides comprises a magazine for a stack of such articles and a dispensing block carrying the magazine and reciprocable relative to a spring blade running in a groove in the top of the block and under the magazine. The depth of the grooves changes so that the front of the blade rises as it travels in the groove, under the magazine, from a projection less than the thickness of article to a projection greater than that thickness, so as to engage and push only the lowermost article under a resilient barrier that restrains other articles in the stack.Also disclosed is an automatic microscope slide coverslipping machine incorporating the dispenser.
摘要翻译： 用于薄平坦刚性制品的分配器，例如用于显微镜载玻片的玻璃盖滑动件，包括用于这种物品的堆叠的盒，以及承载盒的分配块，并相对于在块的顶部中的槽中运行的弹簧片可往复运动， 该杂志。 凹槽的深度改变，使得当刀片的前部从小于制品厚度的突起移动到大于该厚度的突出部时，刀片的前部在槽中在槽内行进时上升，以便仅接合和推动 最下面的物品在弹性屏障下，限制堆叠中的其他物品。
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公开(公告)号：US4705630A
公开(公告)日：1987-11-10
申请号：US871530
申请日：1986-06-06
CPC分类号： G01N1/2813 , G01N2001/2846
摘要： Centrifugation apparatus characterized by a carrier including both a bucket to accommodate a sample chamber and means for supporting a specimen container adjacent to the sample chamber so that material in the specimen container can be pre-centrifuged and then transferred to the sample chamber for centrifugation therein, using automated transfer means. The apparatus may include a disaggregator cooperable with the specimen container to disperse the contents of the latter prior to pre-centrifugation. The transfer means may be a pipette with arrangements for both external and internal flushing and measured dilution of a transferred sample. There may also be means for supplying treatment fluid to a reservoir of the sample chamber.
摘要翻译： 该离心装置的特征在于包括容纳样品室的桶的载体和用于支撑与样品室相邻的样本容器的装置，使得样品容器中的材料可以被预先离心，然后转移到样品室以进行离心， 使用自动转移手段。 该装置可以包括与样品容器配合的分解器，以在预离心之前分散其中的内容物。 转移装置可以是移液管，其具有用于外部和内部冲洗和测量的转移样品的稀释的布置。 还可以存在用于将处理流体供应到样品室的储存器的装置。
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公开(公告)号：US4604964A
公开(公告)日：1986-08-12
申请号：US701818
申请日：1985-02-19
申请人： Alan J. Gordon , David W. Sterritt , Robert Evans
发明人： Alan J. Gordon , David W. Sterritt , Robert Evans
摘要： A tissue processing apparatus comprises a processing chamber (1), a plurality of reagent containers (5), only one of which is illustrated, and a selector valve (2) for sequentially connecting the processing chamber (1) to each of the said reagent containers (5) to transfer fluid between the chamber and such a container. A vacuum/compression pump (6) and a changeover valve system connected to each of the reagent containers (5) and to the processing chamber (1) is operable to promote reagent flow in a required direction between a reagent container (5) and a processing chamber (1) while maintaining a closed circuit for reagent and gas displaced by the pump between the chamber and the container.
摘要翻译： 组织处理装置包括处理室（1），多个试剂容器（5），仅示出其中一个;以及选择阀（2），用于将处理室（1）顺序地连接到每个所述试剂 容器（5）在腔室和这种容器之间传送流体。 连接到每个试剂容器（5）和处理室（1）的真空/压缩泵（6）和切换阀系统可操作以促进试剂在试剂容器（5）和 处理室（1），同时保持由泵在容器和容器之间移动的试剂和气体的闭合回路。
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公开(公告)号：US4778442A
公开(公告)日：1988-10-18
申请号：US501997
申请日：1983-06-07
申请人： Alan J. Gordon
发明人： Alan J. Gordon
CPC分类号： B04B5/0421
摘要： A centrifuge system, especially for centrifugation of pathologically dangerous material, is characterized by a centrifuge head adapted to contain a carrier liquid and so formed and shaped that upon rotation of the head about its axis of symmetry the carrier liquid is distributed in a configuration to support one or more sealed sample containers wholly by floatation. The distribution of the carrier liquid in the rotating head may be as an annular body of constant cross section, or as two or more bodies accommodated in fluidly linked chambers in the head. The sample containers may be rigid and for instance tubular, or flexible and for instance bag-like.
摘要翻译： 特别是用于病理危险物质的离心的离心机系统的特征在于，离心机头部适于容纳载体液体并形成并成形，使得当头部围绕其对称轴线旋转时，载体液体被配置成支撑 一个或多个密封的样品容器完全通过浮选。 载体液体在旋转头中的分布可以是恒定横截面的环形体，或者作为容纳在头部中的流体连通的腔室中的两个或多个主体。 样品容器可以是刚性的，例如管状或柔性的，例如袋状。
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公开(公告)号：US4228926A
公开(公告)日：1980-10-21
申请号：US883465
申请日：1978-03-06
申请人： Alan J. Gordon
发明人： Alan J. Gordon
IPC分类号： B05C11/10 , B05C17/00 , B05C17/005 , B05D1/26 , B67D3/00
CPC分类号： B05D1/26 , B05C11/1013 , B05C17/002
摘要： Viscous fluids are dispensed intermittently in regulated quantities from a body of such a fluid held under maintained pressure and under the control of a control valve in a fluid flow path positioned at a significant distance upstream of a discharge point, the flow path between the control valve and the discharge point having its contained volume adjusted in coordination with operation of the control valve so that as the valve closes the volume is increased to prevent exudation of fluid at the discharge point.
摘要翻译： 粘性流体以一定体积的间隔从间歇地保持的压力下保持的压力下并且在位于排放点上游位置处于显着距离的流体流动路径中的控制阀的控制下被间歇地分配，控制阀 并且排出点与其控制阀的操作协调地调节其容积，从而当阀关闭时增加体积，以防止流体在排放点渗出。
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公开(公告)号：US4696743A
公开(公告)日：1987-09-29
申请号：US871061
申请日：1986-06-05
CPC分类号： G01N1/2813 , G01N2001/2846
摘要： Centrifugation apparatus comprising a sample chamber, a deposit-receiving surface such as a slide and a filter card having an aperture adapted to define on that surface a deposition area communicating with the sample chamber is characterized by the feature that liquid flow paths in the filter card from the perimeter of the aperture are selectively restricted in cross section so as to promote constant velocity flow of liquid, from the sample chamber into the card, in directions substantially normal to all points on the periphery of the aperture. This promotes uniform deposition of solids on the deposit-receiving surface throughout the deposition area, to facilitate inspection of the deposit and, particularly, automated optical scanning of the deposit. The cross sectional restrictions may be accomplished by local removal of filter card material; by local compression of the filter card; or by local impregnation of the card material with an occlusive agent.
摘要翻译： 离心装置包括样品室，诸如滑块的沉积物接收表面和具有适于在该表面上限定与样品室连通的沉积区域的孔的过滤卡，其特征在于，过滤卡中的液体流动路径 从孔的周边被选择性地限制在横截面中，以便促进液体从样品室到基本上垂直于孔周边上的所有点的方向的恒定速度流动。 这促进固体在整个沉积区域的沉积物接收表面上的均匀沉积，以便于沉积物的检查，特别是沉积物的自动光学扫描。 横截面限制可以通过局部去除过滤卡材料来实现; 通过本地压缩过滤卡; 或通过用封闭剂局部浸渍卡片材料。
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