- 专利标题： Methods for Detecting Symmetrical Dimethylarginine
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申请号： US17705924申请日： 2022-03-28
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公开(公告)号： US20220221446A1公开(公告)日： 2022-07-14
- 发明人: Murthy V.S.N. Yerramilli , Mahalakshmi Yerramilli , Michael Atkinson , Kwok Kam Yeung
- 申请人： IDEXX Laboratories, Inc.
- 申请人地址： US ME Westbrook
- 专利权人： IDEXX Laboratories, Inc.
- 当前专利权人： IDEXX Laboratories, Inc.
- 当前专利权人地址： US ME Westbrook
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07C279/12 ; C07K16/44 ; G01N33/68 ; G01N33/543
摘要：
Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.
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