发明申请
- 专利标题： Anti-Perp Antibody
- 专利标题（中）： 抗Perp抗体
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申请号： US11628745申请日： 2005-06-07
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公开(公告)号： US20090258007A1公开(公告)日： 2009-10-15
- 发明人: Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susumu Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
- 申请人： Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susumu Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
- 申请人地址： JP Chiyoda-ku, TOKYO JP TOKYO
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.,President National Cancer Center
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.,President National Cancer Center
- 当前专利权人地址： JP Chiyoda-ku, TOKYO JP TOKYO
- 优先权： JP2004-168116 20040607
- 国际申请： PCT/JP2005/010405 WO 20050607
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C12N5/12 ; C07H21/04 ; C12N15/63 ; C12N5/10 ; C12P21/00 ; G01N33/53 ; C12Q1/68 ; A61P35/00
摘要：
The present invention provides an antibody which specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by PERP (p53 apoptosis effector related to PMP-22) gene and binds to the extracellular region. The antibody of the present invention is useful for treatment of various diseases which highly expresses a polypeptide encoded by the PERP gene. Also, a polypeptide encoded by the PERP gene or a cell expressing the polypeptide can be specifically detected by an immunological method using the antibody, so that the antibody is useful for diagnosis of various diseases related to PERP.
公开/授权文献
- US08093361B2 Anti-perp antibody 公开/授权日：2012-01-10
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