发明申请
- 专利标题: PEPTIDES AND COMPOUNDS THAT BIND TO A RECEPTOR
- 专利标题(中): 与受体结合的肽和化合物
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申请号: US12103377申请日: 2008-04-15
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公开(公告)号: US20090214489A1公开(公告)日: 2009-08-27
- 发明人: William J. Dower , Ronald W. Barrett , Steven E. Cwirla , David J. Duffin , Christian M. Gates , Sherril S. Haselden , Larry C. Mattheakis , Peter J. Schatz , Christopher R. Wagstrom , Nicholas C. Wrighton
- 申请人: William J. Dower , Ronald W. Barrett , Steven E. Cwirla , David J. Duffin , Christian M. Gates , Sherril S. Haselden , Larry C. Mattheakis , Peter J. Schatz , Christopher R. Wagstrom , Nicholas C. Wrighton
- 主分类号: A61K35/12
- IPC分类号: A61K35/12 ; C07K7/06 ; C07K1/107 ; A61K38/08 ; C12N5/00 ; C12N5/08 ; C07K7/64 ; A61P7/00
摘要:
Described are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.
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