发明申请
- 专利标题： DIFFERENTIALLY EXPRESSED GENES INVOLVED IN ANGIOGENESIS, THE POLYPEPTIDES ENCODED THEREBY, AND METHODS OF USING THE SAME
- 专利标题（中）： 与生物降解有关的差异表达基因，编码的多肽及其使用方法
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申请号： US11927609申请日： 2007-10-29
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公开(公告)号： US20080241835A1公开(公告)日： 2008-10-02
- 发明人: Fuad Mehraban , Mary Gerritsen , Luca Rastelli
- 申请人： Fuad Mehraban , Mary Gerritsen , Luca Rastelli
- 申请人地址： US CA South San Francisco US CT New Haven
- 专利权人： Genentech, Inc.,CuraGen Corp.
- 当前专利权人： Genentech, Inc.,CuraGen Corp.
- 当前专利权人地址： US CA South San Francisco US CT New Haven
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/00
摘要：
The present invention is directed to nucleic acid sequences and the polypeptides encoded thereby that are differentially expressed in angiogenesis. Also provided are methods for stimulating or inhibiting angiogenesis in mammals, including humans. Pharmaceutical compositions based on polypeptides, agonists, or antagonists thereto are also provided. Additionally, the invention also provides methods for diagnosing and treating angiogenic disorders including, but not limited to, wound healing and cancer.
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