- 专利标题： 7-membered aza-heterocyclic containing δ-opioid receptor modulating compounds, methods of using and making the same
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申请号： US16486539申请日： 2018-02-15
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公开(公告)号： US11225487B2公开(公告)日： 2022-01-18
- 发明人: Aimee Crombie Speerschneider , Dennis Shinji Yamashita , Philip Michael Pitis , Michael John Hawkins , Guodong Liu , Tamara Ann Miskowski Daubert , Catherine C. K. Yuan , Robert Borbo Kargbo , Robert Jason Herr , Donna Romero
- 申请人： Trevena, Inc.
- 申请人地址： US PA Chesterbrook
- 专利权人： Trevena, Inc.
- 当前专利权人： Trevena, Inc.
- 当前专利权人地址： US PA Chesterbrook
- 代理机构： Troutman Pepper Sanders Hamilton LLP
- 国际申请： PCT/US2018/018303 WO 20180215
- 国际公布： WO2018/152286 WO 20180823
- 主分类号： C07D487/08
- IPC分类号： C07D487/08 ; A61P25/22 ; A61P23/00 ; A61P25/24 ; C07D223/04 ; C07D403/12 ; C07D403/14 ; C07D405/14 ; C07D417/14
摘要：
The present embodiments are directed, in part, to compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinsons Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.
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