The invention discloses a hub bearing suitable for an off-road pickup. The hub bearing suitable for the off-road pickup comprises a hub bearing body. The hub bearing body comprises a flange inner ringand a flange outer ring which are arranged in a clearance manner. An installation ring is arranged on the flange inner ring in a sleeved manner. A rotating piece is arranged between the installationring and the flange outer ring. One end of the flange outer ring is provided with a first seal portion, and the first seal portion is used for guaranteeing the seal performance and protecting the rotation piece against disturbance and damage from the external environment. The other end of the flange outer ring and the flange inner ring are sealed into a whole through a second seal portion, so thatmuddy water accumulation is avoided. The hub bearing suitable for the off-road pickup has the advantages that an inner seal piece and an outer seal piece are utilized to conduct seal, the protectivecover and a second seal ring are utilized for further seal, so that it is avoided that splashing stone influences the inner seal piece, dust, muddy water and the like are prevented from being accumulated at the outer seal piece, the seal effect is good, and the service life is long; a tooth ring is integrated into the hub bearing body, protection of the toothed ring is improved, and the reading precision of a front wheel rotation speed sensor is improved.