The invention discloses a hydraulic driving mould frame for positioning and manufacturing a reinforcing bar skeleton of a box girder, comprising a pedestal, a reinforcing bar skeleton, a longitudinalpositioning channel steel, two groups of die frame mold frames arranged opposite to each other, and a hydraulic system. The longitudinal positioning channel steel is used for positioning the reinforcing bar skeleton, and the longitudinal positioning channel steel is arranged on the pedestal. The longitudinal positioning channel steel is provided with bottom surface supporting channel steel at bothends of the longitudinal positioning channel steel; each bottom support channel steel is also connected with a guide rail; the hydraulic system is used to drive the mold carrier mold frame such thatthe mold carrier mold frame can be translated along the guide rail. The invention has the advantages of simple and quick construction, movable support, and adjustable mold closing position of the movable support according to site requirements, simple operation and strong adaptability. A hydraulic driving system is installed at the bottom of the bracket, which can make the bracket move in translation and realize mold closing and opening conveniently. It can not only ensure the reinforcement skeleton of the small box girder to meet the design requirements but also improve the positioning accuracy of the reinforcement skeleton.