The invention relates to a piezoelectric multi-degree-of-freedom hybrid drive driver and belongs to the fields of precision drive positioning and precision machining. Arbitrary combined motion in two degrees of freedom of precision rotation and progressive linear motion can be achieved. The piezoelectric multi-degree-of-freedom hybrid drive driver mainly comprises a stator unit, a rotor unit and a linear output shaft, wherein aligned piezoelectric clamping mechanisms and linear drive mechanism are arranged in the stator unit. A piezoelectric wafer is driven to reversely vibrate quickly after being slowly curved through sawtooth-wave power supply excitation, and piezoelectric vibrators which are symmetrically distributed at two ends of the output shaft vibrate clockwise/ counterclockwise, so that directional rotation of the output shaft around the axis is achieved. Progressive linear motion of the output shaft along the axial direction is achieved through controlling the expansion and concentration amount of an annular piezoelectric stack at the bottom of the stator unit and matching with the time sequence of actions of clamping mechanisms at the upper and lower layers. The piezoelectric multi-degree-of-freedom hybrid drive driver can be applied to the field of precision drive positioning and machining, and has the advantages of being high in bearing capacity, long in working stroke, high in control efficiency, stable in work and high in output precision.