The invention relates to a handle universal adjusting elbow clamp. The handle universal adjusting elbow clamp comprises a universal joint connecting rod, a handle, a universal joint, a fixed ring and a clamping rod; one end of the clamping rod penetrates through the universal joint to rotationally connect with the handle; the fixed ring coats the universal joint; the universal joint is rotationally connected with the fixed ring; and the universal joint connecting rod is rotationally connected with the universal joint and the handle. The handle universal adjusting elbow clamp realizes that the handle can rotate in any peripheral direction to clamp a punched part in any direction through the universal joint and the handle structure, freely determines the clamping trajectory, and can achieve the same clamping effect.