公开(公告)号：US12060334B2

公开(公告)日：2024-08-13

申请号：US17692536

申请日：2022-03-11

申请人： University of Florida Research Foundation, Incorporated

发明人： Robert William Huigens, III ,  Hongfen Yang

IPC分类号： C07D241/46 ,  A61K31/498

CPC分类号： C07D241/46

摘要： The present invention provides phenazine derivatives, such as compounds of Formula (I). The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides compositions, kits, uses, and methods that involve the compounds of the invention, which may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.

公开(公告)号：US20230411662A1

公开(公告)日：2023-12-21

申请号：US18031751

申请日：2020-11-30

申请人： CMBLU Energy AG

发明人： Olga Ekkert ,  Evgeny Larionov ,  Jan Hartwig ,  Eduard Baal

IPC分类号： H01M8/18 ,  H01M8/04276 ,  C07D241/46 ,  C01C3/12

CPC分类号： H01M8/188 ,  H01M8/04276 ,  C07D241/46 ,  C01C3/12

摘要： The present invention provides a process for the regeneration of an electrolyte solution of a redox-flow battery containing at least one (preferably substituted) phenazine compound, said process comprising at least one of the following steps (a), (b) and (c): (a) treatment of the electrolyte solution to be regenerated in order to convert organic degradation compounds contained therein to a (substituted) phenazine compound; (b) removal of precipitated material from the electrolyte solution and subsequent modification of the precipitated organic degradation compounds to obtain a (substituted) phenazine compound; and (c) separation of redox active compounds other than (substituted) phenazine compounds in particular inorganic electrolytes, from an electrolyte solution containing (substituted) phenazine compounds, and/or separation of (substituted) phenazine compounds from a solution containing redox active compounds other than (substituted) phenazine compounds.

公开(公告)号：US20220336811A1

公开(公告)日：2022-10-20

申请号：US17634314

申请日：2020-08-13

申请人： SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

发明人： Ki Suk KANG ,  Se Chan LEE ,  Ji Hyun HONG

IPC分类号： H01M4/60 ,  H01M10/0525 ,  C07C255/31 ,  C07D241/46

摘要： Provided are a cathode active material for secondary batteries, the cathode active material comprising a charge-transfer complex in which an electron donor and an electron acceptor are bonded to each other, wherein the electron donor and the electron acceptor are bonded to each other by intermolecular interaction, and a method of producing the cathode active material.

公开(公告)号：US20220289689A1

公开(公告)日：2022-09-15

申请号：US17692536

申请日：2022-03-11

申请人： University of Florida Research Foundation, Incorporated

发明人： Robert William Huigens, III ,  Hongfen Yang

IPC分类号： C07D241/46

摘要： The present invention provides phenazine derivatives, such as compounds of Formula (I). The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides compositions, kits, uses, and methods that involve the compounds of the invention, which may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.

公开(公告)号：US11319483B2

公开(公告)日：2022-05-03

申请号：US16240490

申请日：2019-01-04

申请人： CANON KABUSHIKI KAISHA

发明人： Kenji Yamada ,  Satoshi Igawa ,  Wataru Kubo ,  Yuto Ito ,  Isao Kawata

IPC分类号： G02F1/153 ,  C09K9/02 ,  C07D241/46 ,  G02F1/155 ,  E06B9/24 ,  E06B3/67 ,  G02F1/1516

摘要： An organic compound represented by the following general formula is provided. In the above formula (1), R11 to R15 each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, an aryloxy group, an aralkyl group, an acyl group, or a halogen atom provided that at least one of R11, R13, and R15 represents the alkoxy group or the aryloxy group; and R11 to R15 may form a ring structure therebetween. R5 and R6 each independently represent an alkyl group, an aryl group, or an aralkyl group. In addition, R21 to R24 each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, an aryloxy group, an aralkyl group, an acyl group, or a halogen atom and may form a ring structure therebetween. The above groups except the acyl group may be substituted when necessary.

公开(公告)号：US11130741B2

公开(公告)日：2021-09-28

申请号：US16312627

申请日：2017-06-22

申请人： Bioimics AB

发明人： Leif Kirsebom ,  Ram Shankar Upadhayaya ,  Raghava Reddy Kethiri ,  Anders Virtanen

IPC分类号： C07D279/28 ,  C07D417/12 ,  C07D417/14 ,  C07D279/20 ,  C07D513/04 ,  C07D513/06 ,  A61P33/00 ,  A61P31/04 ,  A61P31/10 ,  C07D241/46 ,  C07D265/38 ,  C07D413/12 ,  C07D417/04 ,  C07D417/06

摘要： The present invention relates to heterocyclic compounds of Formula I useful as anti-infective agents. The present invention further relates to a method of treating an infection by administering such compounds, and to pharmaceutical compositions comprising such compounds.

公开(公告)号：US11053205B2

公开(公告)日：2021-07-06

申请号：US16486694

申请日：2018-02-17

申请人： University of Florida Research Foundation, Incorporated

发明人： Robert William Huigens, III ,  Aaron Garrison ,  Yasmeen Abouelhassan ,  Hongfen Yang ,  Gena Burch

IPC分类号： A61K31/498 ,  C07D241/46 ,  A61P31/06 ,  C07D403/06 ,  C07D501/16 ,  C07H17/02 ,  A61K45/06

摘要： The present invention provides novel phenazine derivatives, such as compounds of Formula (I) (e.g., Formulae (II)-(XIX)), and pharmaceutically acceptable salts thereof. The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides pharmaceutical compositions, kits, uses, and methods that involve the compounds of the invention and may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.

公开(公告)号：US10950799B2

公开(公告)日：2021-03-16

申请号：US15329851

申请日：2015-07-30

申请人： Konica Minolta, Inc.

发明人： Yasuo Miyata ,  Taketo Namikawa ,  Hiroshi Kita

IPC分类号： H01L51/00 ,  C07D219/02 ,  C07D241/46 ,  C07D241/48 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D333/76 ,  C07D401/10 ,  C07D401/12 ,  C07D403/10 ,  C07D403/12 ,  C07D409/10 ,  C07D413/14 ,  C07D417/10 ,  C07D487/04 ,  C07F5/02 ,  C07F7/08 ,  C07F7/10 ,  C09K11/06 ,  H01L51/50 ,  H05B33/20 ,  C07D209/86

摘要： An object of the present invention is to provide an organic electroluminescent element containing an organic layer interposed between an anode and a cathode, the organic layer containing at least one light emitting layer, wherein the at least one light emitting layer contains a π-conjugated compound having an electron donor portion and an electron acceptor portion in the molecule; the π-conjugated compound has a direction vector from an atom having a HOMO orbital in the electron donor portion to an electron cloud of the HOMO orbital, and a direction vector from an atom having a LUMO orbital in the electron acceptor portion to an electron cloud of the LUMO orbital, and the two direction vectors form an angle θ in the range of 90 to 180 degrees; and the π-conjugated compound has a plurality of the electron donor portions or a plurality of the electron acceptor portions.

公开(公告)号：US20200017508A1

公开(公告)日：2020-01-16

申请号：US16441058

申请日：2019-06-14

申请人： Universal Display Corporation

发明人： Hsiao-Fan CHEN ,  Peter WOLOHAN ,  Nicholas J. THOMPSON

IPC分类号： C07D487/04 ,  H01L51/00 ,  C07D209/82 ,  C07D279/22 ,  C07D265/38 ,  C07D241/46 ,  C07D295/033 ,  C07D495/04 ,  C07D491/048 ,  C07D251/24 ,  C07C255/51 ,  C07C211/54

摘要： A compound having a structure of Formula I, is provided. In Formula I, Z1 to Z16 are each CR or N; three consecutive ones of Z1 to Z16 within the same ring cannot be N; each R is independently a hydrogen or a substituent selected from a variety of substituents; at least one R includes and electron donor substituent; at least one R includes an electron acceptor substituent; and any two Rs on the same ring can be joined or fused together to form a ring. Organic light emitting devices, consumer products, formulations, and chemical structures containing the compounds are also disclosed.

公开(公告)号：US10301349B2

公开(公告)日：2019-05-28

申请号：US14673118

申请日：2015-03-30

申请人： BIOSEARCH TECHNOLOGIES, INC.

发明人： Ronald M. Cook ,  Matt Lyttle ,  Daren Dick

IPC分类号： C07H21/00 ,  C07D241/46 ,  C07F9/09 ,  C07F9/24 ,  C09B31/043 ,  C09B56/00 ,  G01N33/542 ,  C12Q1/6818 ,  G01N33/58 ,  C07C245/08 ,  C09B56/12 ,  C40B40/00

摘要： The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially non-fluorescent. Also provided are methods of using the BHQs, probes incorporating the BHQs and methods of using the probes.