公开(公告)号：US3833594A

公开(公告)日：1974-09-03

申请号：US36856273

申请日：1973-06-11

Applicant: SQUIBB & SONS INC

Inventor： HOEHN H ,  DENZEL T

IPC: C07D261/14 ,  C07D49/18

CPC classification number: C07D261/14

Abstract: NEW AMINO DERIVAIVES OF PYRAZOLO 3,4-B!PYRIDINE-5CARBOXYLIC ACIDS AND ESTERS HAVE THE GENERAL FORMULA

1-R1,3-R2,4-(R3-N(-R4)-),5-(RO-CO-),6-R5-PYRAZOLO(3,4-B)

PYRIDINE

THEY ARE USEFUL AS ATATACTIC, ANALGESIC AND ANTIINFLAMMATORY AGENTS. IN ADDITION, THE NEW COMPOUNDS INCREASE THE INTRACELLULAR CONCENTRATION OF ADENOSINE-3'',5''-CYCLIC MONOPHOSPHATE.

公开(公告)号：US3828068A

公开(公告)日：1974-08-06

申请号：US31067072

申请日：1972-11-29

Applicant: TENNECO CHEM

Inventor： MINIERI P

IPC: C07D231/56 ,  C07D49/18

CPC classification number: C07D231/56

Abstract: 1-((R-)2N-CO-O-CH2-),3-Y,(X)N-1H-INDAZOLE


WHEREIN X REPRESENTS HALOGEN, NITRO, AMINO, ACETAMINO, OR (HALOBENZYLIDENE)AMINO; N REPRESENTS AN INTEGER IN THE RANGE OF 0 TO 3; EACH R REPRESENTS HYDROGEN, LOWER ALKYL, PHENYL, HALOPHENYL, OR NITROPHENYL; WHEN N IS 0, Y REPRESENTS HALOGEN; AND WHEN N IS 1 TO 3, Y REPRESENTS HYDROGEN OR HALOGEN AND USED TO CONTROL THE GROWTH OF FUNGI AND BACTERIA. ILLUSTRATIVE OF THESE COMPOUNDS IS (3-CHLOROINDAZOLYL-N1-METHYL) N-METHYLCARBAMATE.
COMPOUNDS THAT HAVE THE STRUCTURAL FORMULA

公开(公告)号：US3784570A

公开(公告)日：1974-01-08

申请号：US3784570D

申请日：1970-08-18

Applicant: BAYER AG

Inventor： SCHELLHAMMER C

IPC: C09B57/02 ,  C07D231/16 ,  C07D49/18 ,  C07D55/04

CPC classification number: C07D231/16

Abstract: OPTICAL BRIGHTENERS ON THE BASIS OF 4-CHLORO-PYRAZOLYL(1) COMPOUNDS HAVING THE FORMULA: P-F-Q IN WHICH P STANDS FOR A RADICAL WHICH IS LINKED TO A CARBON ATOM OF THE RADICAL F AND CORRESPONDS TO FHT FORMULA: 3-R1,4-(CL-),5-R2-PYRAZOL-1-YL IN WHICH R1 AND R2 REPRESENT HYDROGEN, AND ALKYL RADUICAL, A CYCLOALKYL, ARALKYL OR ARYL RADICAL; F REPRESENTS THE RADICAL OF A FLUORESCENT SYSTEM; Q REPRESENTS HYDROGEN OR A RADICAL WITH THE SAME MEANING AS P LINKED TO A CARBON ATOM OF THE RADICAL F.

公开(公告)号：US3763180A

公开(公告)日：1973-10-02

申请号：US3763180D

申请日：1970-01-23

Applicant: RHONE POULENC SA

Inventor： SAULI M

IPC: A01N57/32 ,  C07D231/56 ,  C07F9/6503 ,  C07D49/18

CPC classification number: C07D231/56 ,  C07F9/65038

Abstract: ORGANOPHOSPHORUS COMPOUNDS OF THE FORMULA:

1-((C2H5-O)2-P(=S)-),3-R1,5-R2-INDAZOLE

WHEREIN R1 REPRESENTS HALOGEN, ALKYL OF 1 THROUGH 4 CARBON ATOMS, PHENYL, CYANO, CARBAMOYL OR THIOCARBAMOYL, AND R2 REPRESENTS HYDROGEN, HYDROGEN, HALOGEN OR NITRO, POSSESS USEFUL INSECTICIAL PROPERTIES, IN PARTICULAR AGAINST DIPTERA, COLEOPTERA, LEPIDOPTERA, HEMIPTERA AND ORTHOPTERA, AND FUNGICIDAL PROPERTIES, IN PARTICULAR AGAINST CUCUMBER MILDEW AND WHEAT RUST.

公开(公告)号：US3726896A

公开(公告)日：1973-04-10

申请号：US3726896D

申请日：1970-05-06

Applicant: SZABO HNOS KESSLER & CIA

Inventor： AMATO J ,  STAMBURGO M ,  FISCHER E

IPC: C07D231/56 ,  C07D49/18

CPC classification number: C07D231/56

Abstract: 1 BENZYL 3 (ALPHA HYDROXY PROPOXY) INDAZOLE, COMPOUNDS AND COMPOSITIONS INCLUDING 1 BENZYL 3 (BETA, ALPHA DIHYDROXY PROPOXY) INDAZOLE AND THE METALLIC SALTS OF THEIR CORRESPONDING HEMISUCCINATES IN THE PRIMARY OR SECONDARY FORM, UTILITY OF THE COMPOUNDS INCLUDES ANALGESICS, AND ANTI-INFLAMMATORIES.

公开(公告)号：US3704241A

公开(公告)日：1972-11-28

申请号：US3704241D

申请日：1970-11-17

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NOGUCHI SHUNSAKU ,  KISHIMOTO SHOJI

IPC: C07D231/12 ,  C07D49/18

CPC classification number: C07D231/12 ,  Y10S514/87

Abstract: 4-PYRAZOLE ACETIC ACID OR ESTERS THEREOF OF THE FORMULA:

R1-NHNH2 (III)SP@ WHEREIN R1 HAS THE SAME MEANING AS ABOVE, AND, IF DESIRED, HYDROLYZING THE THUS OBTAINED COMPOUND. THE COMPOUNDS POSSESS ANTI-INFLAMMATORY AND ANALGESIC ACTION.

WHEREIN R3 REPRESENTS ALKYL, WITH A HYDRAZINE OF THE FORMULA:

(PHENYL-CO-CH(-CH2-COO-R3)-CO-)BENZENE

WHEREIN R1 IS HYDROGEN, LOWER ALKYL, ARYL OR ARALKYL, THE AROMATIC RING OF THE SAID ARYL OR ARALKYL BEING SUBSTITUTED OR UNSUBSTITUTED, AND R2 IS HYDROGEN OR ALKYL ARE PREPARED BY REACTING A B,B-DIBENZOYLPROPIONATE OF THE FORMULA:

1-R1,3,5-DI(PHENYL),4-(R2-OOC-CH2-)PYRAZOE

公开(公告)号：US3691180A

公开(公告)日：1972-09-12

申请号：US3691180D

申请日：1970-07-31

Applicant: CIBA GEIGY CORP

Inventor： BLATTER HERBERT MORTON ,  LUCAS ROBERT ARMISTEAD

IPC: C07D231/56 ,  C07D49/18

CPC classification number: C07C243/00 ,  C07D231/56

Abstract: Cycloalkano(c)pyrazoles, e.g. those of the formula

QUATERNARIES AND SALTS THEREOF, EXHIBIT ANTIVIRAL EFFECTS AND ARE ALSO VALUABLE INTERMEDIATES IN THE PREPARATION OF OTHER PHARMACOLOGICALLY USEFUL COMPOUNDS.

公开(公告)号：US3660424A

公开(公告)日：1972-05-02

申请号：US3660424D

申请日：1969-06-16

Applicant: CIBA GEIGY CORP

Inventor： KABAS GUGLIELMO ,  ZWEIDLER REINHARD

IPC: C08G63/685 ,  C08K5/3442 ,  C08K5/3445 ,  C08L67/02 ,  C07D49/18

CPC classification number: C08K5/3445 ,  C08G63/6854 ,  C08K5/3442 ,  C08L67/02 ,  C08L2666/70

Abstract: 3 - PHENYL - 7 - (4''-CHLOROPYRAZOLYL-(1''))-COUMARINS WHICH BEAR FURTHER SUBSTITUENTS ESPECIALLY AT THE 3''AND 5''-POSITION OF THE PYRAZOLYL NUCLEUS, AND DESCRIBED AS OPTICAL BRIGHTENERS AFFORDING SUPERIOR DEGREE OF WHITENESS AND FLUORESCENCE NUMBER AS WELL AS BETTER FASTNESS TO CHLORITE BLEACHING BATHS ON SUCH SUBSTATES AS POLYESTER AND OTHER POLYMERIC ORGANIC MATERIALS. A PREFERRED COMPOUND IS 3-PHENYL-7-(3''-METHYL-4''-CHLOROPYRAZOLYL-(1'')COUMARIN. A METHOD OF BRIGHTENING POLYMERIC MATERIALS, E.G. FIBERSS ARE FILMS WITH THE WORD COMPOUND AS WELL AS POLYMERIC MATERIALS BRIGHTENED THEREWITH ARE ALSO DISCLOSED.

公开(公告)号：US3637736A

公开(公告)日：1972-01-25

申请号：US3637736D

申请日：1966-10-25

Applicant: TENNECO CHEM

Inventor： MINIERI PASQUALE P

IPC: C07D231/56 ,  C07F9/6503 ,  C07D49/18

CPC classification number: C07F9/65031 ,  C07D231/56

Abstract: N''-SUBSTITUTED-6-NITROINDAZOLES ARE USEFUL IN THE CONTROL OF THE GROWTH OF UNDESIRABLE FUNGI, BACTERIA, PLANTS AND INSECTS. AMONG HTE MOST ACTIVE OF THESE COMPOUNDS ARE N''-THIOCYANATOMETHYL-6-NITROINDAZOLE AND N''-CHLOROMETHYL-3-CHLORO-6-NITROINDAZOLE.

公开(公告)号：US3487083A

公开(公告)日：1969-12-30

申请号：US3487083D

申请日：1967-07-06

Applicant: BURROUGHS WELLCOME CO

Inventor： CRESSWELL RONALD M ,  SCHNAPPER MELVIN

IPC: A61K31/505 ,  C07C255/30 ,  C07D231/38 ,  C07D487/04 ,  C07D51/42 ,  A61K27/00 ,  C07D49/18

CPC classification number: C07D231/38 ,  C07C255/00