公开(公告)号：US5155135A

公开(公告)日：1992-10-13

申请号：US446606

申请日：1989-12-06

申请人： Martin Anderson ,  Antony G. Brinnand ,  Pieter A. Verbrugge

发明人： Martin Anderson ,  Antony G. Brinnand ,  Pieter A. Verbrugge

IPC分类号： A01N47/34 ,  C07C273/18 ,  C07C275/62 ,  C07C335/28

CPC分类号： C07C335/28 ,  A01N47/34 ,  C07C273/1854 ,  C07C275/62

摘要： This invention provides benzamide compounds of general formula ##STR1## wherein each of A and B independently represents a hydrogen or halogen atom, X represents an oxygen or a sulphur atom, n is 0, 1, 2, 3 or 4, each Z moiety independently represents a halogen atom or a C.sub.1-6 alkyl group, and Y represents a C.sub.1-6 haloalkyl group, a C.sub.1-6 haloalkoxy group, a group of formula ##STR2## wherein P is 0, 1 or 2, each Z' moiety independently represents a halogen atom or a C.sub.1-6 alkyl group, Y' represents a C.sub.1-6 haloalkyl, C.sub.1-6 haloalkoxy, nitro or cyano group and Q represents N or C-H, or, when n is 2 or 3, Y may also be a halogen atom; processes for their preparation; and their use as pesticides.

公开(公告)号：US4997981A

公开(公告)日：1991-03-05

申请号：US424300

申请日：1989-04-20

申请人： Paul D. Hill ,  William M. Snyder ,  Stanley W. Walinsky

发明人： Paul D. Hill ,  William M. Snyder ,  Stanley W. Walinsky

IPC分类号： C07C335/28 ,  C07D417/04

CPC分类号： C07D417/04 ,  C07C335/28

摘要： An amine substituion process for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole, for precursor N-(pentylamidino)thiourea, and for analogs thereof of said compounds.

摘要翻译： PCT No.PCT / US86 / 02308 Sec。 371日期：1989年4月20日 102（e）日期1989年4月20日PCT提交1986年10月29日PCT公布。 出版物WO88 / 03141 日期：1988年5月5日。用于前体N-（戊基脒基）硫脲及其类似物的2-（1-戊基-3-胍基）-4-（2-甲基-4-咪唑基）噻唑的胺取代方法 所述化合物。

公开(公告)号：US4908383A

公开(公告)日：1990-03-13

申请号：US356665

申请日：1989-05-23

申请人： Jozef Drabek ,  Josef Ehrenfreund

发明人： Jozef Drabek ,  Josef Ehrenfreund

IPC分类号： A01N47/34 ,  C07C335/28 ,  C07C335/38

CPC分类号： A01N47/34 ,  C07C335/28 ,  C07C335/38 ,  C07C2101/08 ,  C07C2101/10

摘要： Novel N-phenyl-N-carboxythioureas of the formula I ##STR1## in which R.sub.1 and R.sub.2 each represents C.sub.1 -C.sub.10 alkyl, C.sub.3 -C.sub.7 cycloalkyl or C.sub.5 -C.sub.6 cycloalkenyl,R.sub.3 represents hydrogen, halogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 alkoxy or C.sub.1 -C.sub.10 alkylthio,R.sub.4 represents C.sub.1 -C.sub.10 alkyl, C.sub.2 -C.sub.10 alkenyl, C.sub.2 -C.sub.10 alkynyl or phenyl-C.sub.1 -C.sub.7 alkyl; C.sub.1 -C.sub.10 alkyl, C.sub.2 -C.sub.10 alkenyl, C.sub.2 -C.sub.10 alkynyl or phenyl-C.sub.1 -C.sub.7 alkyl each mono- or poly-substituted by halogen or interrupted one or several times by oxygen and/or sulphur; C.sub.3 -C.sub.8 cycloalkyl; or C.sub.3 -C.sub.8 cycloalkyl mono- or poly-substituted by halogen or by C.sub.1 -C.sub.5 alkyl, andR.sub.5 represents C.sub.1 -C.sub.10 alkyl; phenyl-C.sub.1 -C.sub.7 alkyl; C.sub.1 -C.sub.10 alkyl or phenyl-C.sub.1 -C.sub.7 alkyl each mono- or poly-substituted by halogen or interrupted one or several times by oxygen and/or sulphur; C.sub.3 -C.sub.8 cycloalkyl; or C.sub.3 -C.sub.8 cycloalkyl mono- or poly-substituted by halogen or by C.sub.1 -C.sub.5 alkyl, processes and salts of corresponding isothioureas as intermediates for their preparation, their use in pest control, and pesticidal compositions that contain at least one compound of the formula I or an active intermediate, are disclosed. The preferred field of application is the control of pests on animals and plants.

摘要翻译： 新的式I的N-苯基-N-羧基硫脲，其中R 1和R 2各自表示C 1 -C 10烷基，C 3 -C 7环烷基或C 5 -C 6环烯基，R 3表示氢，卤素，C 1 -C 10烷基，C 1 -C 10烷氧基 或C 1 -C 10烷硫基，R 4表示C 1 -C 10烷基，C 2 -C 10烯基，C 2 -C 10炔基或苯基-C 1 -C 7烷基; C 1 -C 10烷基，C 2 -C 10烯基，C 2 -C 10炔基或苯基-C 1 -C 7烷基，其各自被卤素单取代或多取代，或被氧和/或硫中断一次或数次; C 3 -C 8环烷基; 或被卤素或C 1 -C 5烷基单取代或多取代的C 3 -C 8环烷基，R 5表示C 1 -C 10烷基; 苯基-C 1 -C 7烷基; 每个被卤素单取代或多取代的C 1 -C 10烷基或苯基-C 1 -C 7烷基，或被氧和/或硫中断一个或几个; C 3 -C 8环烷基; 或被卤素或C 1 -C 5烷基单取代或多取代的C 3 -C 8环烷基，相应的异硫脲的方法和盐作为其制备的中间体，其在病虫害防治中的用途，以及含有至少一种式I化合物或 公开了一种活性中间体。 优选的应用领域是控制动物和植物上的害虫。

公开(公告)号：US4315009A

公开(公告)日：1982-02-09

申请号：US4531

申请日：1979-01-18

申请人： Derrick F. Jones ,  Keith Oldham

发明人： Derrick F. Jones ,  Keith Oldham

IPC分类号： C07D277/20 ,  A61K31/42 ,  A61K31/421 ,  A61K31/425 ,  A61K31/426 ,  A61K31/44 ,  A61K31/535 ,  A61K31/5377 ,  A61P1/04 ,  C07C335/28 ,  C07D263/48 ,  C07D271/06 ,  C07D271/07 ,  C07D277/48 ,  C07D285/08 ,  C07D417/10 ,  C07D417/12

CPC分类号： C07D271/07 ,  C07C335/28 ,  C07D263/48 ,  C07D277/48 ,  C07D285/08

摘要： The guanidine derivative has the formula: ##STR1## where X is O or S: Y is N, CH or CCH.sub.3 : m is 0 or 1: R.sup.1 is hydrogen and R.sup.2 cyano, trifluoroacetyl, C.sub.1-6 alkanoyl, 4,5-dihydro-4-oxothiazol-2-yl or A-B where A is 3,4-dioxocyclobutene-1,2-diyl or C.dbd.Z where Z is oxygen, sulphur, NCN, NNO.sub.2, CHNO.sub.2, NCONH.sub.2, C(CN).sub.2, NCOR.sup.6, NCO.sub.2 R.sup.6, NSO.sub.2 R.sup.6 or NR.sup.7 where R.sup.6 is C.sub.1-6 alkyl and R.sup.7 is hydrogen or C.sub.1-6 alkyl and B is C.sub.1-6 alkyl, alkoxy or alkylthio or NR.sup.8 R.sup.9 where R.sup.8 and R.sup.9 are hydrogen, C.sub.1-10 alkyl, C.sub.3-10 -alkenyl, alkynyl or alkoxyalkyl, C.sub.2-6 (primary hydroxy)alkyl, or, when R.sup.9 is hydrogen, R.sup.8 is 2-[[5-dimethylaminomethylfuran-2-yl]methylthio]-ethylamino or R.sup.8 and R.sup.9 are together a 5- or 6-membered non-aromatic ring optionally containing an additional N or O; or R.sup.1 and R.sup.2 are together imidazolidin-2-ylidene: R.sup.3 is hydrogen or fluorine: R.sup.4 is halogen or methyl: R.sup.5 is hydrogen, C.sub.1-6 alkyl or C.sub.3-10 alkoxyalkyl: and the salts thereof.

摘要翻译： 胍衍生物具有下式：其中X是O或S：Y是N，CH或CCH 3：m是0或1：R 1是氢，R 2是氰基，三氟乙酰基，C 1-6烷酰基， 二氢-4-氧代噻唑-2-基或AB，其中A是3,4-二氧环戊烯-1,2-二基或C = Z，其中Z是氧，硫，NCN，NNO 2，CHNO 2，NCONH 2，C（CN）2， NCOR6，NCO2R6，NSO2R6或NR7，其中R6是C1-6烷基，R7是氢或C1-6烷基，B是C1-6烷基，烷氧基或烷硫基或NR8R9，其中R8和R9是氢，C1-10烷基，C3-10-烯基， 炔基或烷氧基烷基，C2-6（伯羟基）烷基，或当R9为氢时，R8为2 - [[5-二甲氨基甲基呋喃-2-基]甲硫基] - 乙氨基或R8和R9一起为5-或6- 任选地含有另外的N或O的非芳族环; 或R 1和R 2一起是咪唑烷-2-亚基：R 3是氢或氟：R 4是卤素或甲基：R 5是氢，C 1-6烷基或C 3-10烷氧基烷基：及其盐。

公开(公告)号：US4115447A

公开(公告)日：1978-09-19

申请号：US757577

申请日：1977-01-07

申请人： Julius Diamond

发明人： Julius Diamond

IPC分类号： A61K31/17 ,  A61K31/13 ,  A61K31/135 ,  A61K31/16 ,  A61K31/165 ,  A61K31/35 ,  C07C67/00 ,  C07C279/24 ,  C07C279/26 ,  C07C325/00 ,  C07C335/28 ,  C07C127/15

摘要： Antimicrobial compounds are disclosed having the formula:Z--B--Y--B --Z .sup.. nHAwherein B is carbamylguanidino, or thiocarbamylguanidino, Y is a bivalent organic radical selected from the group consisting of C.sub.2 -C.sub.12 alkylene, C.sub.5 -C.sub.12 cycloalkylene, C.sub.5 -C.sub.12 cycloalkylenebis(loweralkyl), C.sub.6 -C.sub.12 arylene and loweralkylarylene, C.sub.7 -C.sub.12 aryleneloweralkyl, and C.sub.8 -C.sub.12 arylenebis(loweralkyl) and Z is selected from the group consisting of C.sub.1 -C.sub.12 alkyl; C.sub.4 -C.sub.12 dialkylaminoalkyl; C.sub.3 -C.sub.12 alkenyl; C.sub.3 -C.sub.12 alkynyl; C.sub.3 -C.sub.12 cycloalkyl, C.sub.4 -C.sub.12 cycloalkylalkyl; C.sub.1 -C.sub.10 alkoxy C.sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 -C.sub.14 ; C.sub.1 -C.sub.10 alkylthio C.sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 -C.sub.14 ; phenoxy C.sub.2 -C.sub.6 alkyl; phenylthio C.sub.2 -C.sub.6 alkyl; C.sub.6 -C.sub.14 aryl; C.sub.7 -C.sub.14 aralkyl; and arylcycloalkyl; and C.sub.6 -C.sub.14 aryl and aralkyl substituted with one or more radicals selected from the group consisting of loweralkyl, trifluoromethyl, loweralkoxy, trifluoromethoxy, phenoxy, loweralkylthio, halo, nitro, cyano, C.sub.2 -C.sub.6 acyl, benzoyl, alkoxycarbonyl, diloweralkylamino, loweralkylsulfonyl, fluorosulfonyl and alkylsulfinyl; n=0, 1/3, 1/2, 2/3, 1, 2 and HA is an inorganic or organic acid.

公开(公告)号：US4075348A

公开(公告)日：1978-02-21

申请号：US790114

申请日：1977-04-22

申请人： Paul William Knapp, Jr.

发明人： Paul William Knapp, Jr.

IPC分类号： A01N47/34 ,  C07C335/28 ,  A01N9/12

CPC分类号： A01N47/34 ,  C07C335/28

摘要： There are provided certain alkyl 3-thio-4{o-[(2,2,2-trihaloethylidene -or 2,2-dihaloalkylidene -or 2,2-dihalohaloalkylidene)amino]phenyl -or substituted phenyl}allophanates, a method for the preparation of the same, and the use of said allophanates as fungicidal agents.

公开(公告)号：US4025652A

公开(公告)日：1977-05-24

申请号：US558186

申请日：1975-03-31

申请人： Julius Diamond ,  George H. Douglas

发明人： Julius Diamond ,  George H. Douglas

IPC分类号： C07C279/24 ,  C07C335/16 ,  C07C335/28 ,  C07C335/34 ,  C07D203/12 ,  C07D295/215 ,  A61K31/17

CPC分类号： C07D295/215 ,  C07C279/24 ,  C07C335/16 ,  C07C335/28 ,  C07C335/34 ,  C07D203/12 ,  Y10S514/867

摘要： A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.

摘要翻译： 描述了一类新的化合物及其制备方法。 这些化合物作为抗腹泻剂具有有价值的性质。

公开(公告)号：US3914284A

公开(公告)日：1975-10-21

申请号：US39965473

申请日：1973-09-21

申请人： BAYER AG

发明人： WIDDIG ARNO ,  KUHLE ENGELBERT ,  SASSE KLAUS ,  SCHEINPFLUG HANS ,  GREWE FERDINAND ,  KASPERS HELMUT ,  FROHBERGER PAUL-ERNST

IPC分类号： C07C335/28 ,  C07C157/09

CPC分类号： C07C335/28

摘要： Ureidophenyl thioureas of the formula:

in which each X independently stands for a halogen atom, alkyl with 1-4 carbon atoms or alkoxy with 1-4 carbon atoms, n stands for 0, 1 or 2, R stands for alkyl with 1-12 carbon atoms, R'' and R'''' each stands independently for a hydrogen atom or alkyl with 1-4 carbon atoms, and R'''''' stands for a hydrogen atom, alkyl with 1 or 2 carbon atoms (which may carry at least one substituent selected from halogen, cyano, alkoxy with up to 4 carbon atoms and alkoxycarbonyl with up to 5 carbon atoms), alkyl with 3 to 18 carbon atoms (which carries at least one substituent selected from halogen, cyano, alkoxy with up to 4 carbon atoms and alkoxycarbonyl with up to 5 carbon atoms), cycloalkyl with 5 to 8 ring carbon atoms, aralkyl (the aryl moiety of which may carry at least one substituent selected from halogen, lower alkyl and lower alkoxy), phenyl (which may carry at least one substituent selected from halogen, lower alkyl and lower alkoxy), acyl with up to 18 carbon atoms (which may be substituted by halogen and/or lower alkyl), aroyl (which may carry at least one substituent selected from halogen, lower alkyl and lower alkoxy), alkylsulfonyl with up to 18 carbon atoms, arylsufonyl (which may carry at least one substituent selected from halogen, amino, lower alkyl and lower alkoxy) or dialkylamino with up to 4 carbon atoms, which possess fungicidial properties and which may be produced by conventional methods.

摘要翻译： 下式的脲基苯基硫脲，其中每个X独立地代表卤素原子，具有1-4个碳原子的烷基，其中每个X独立地代表卤素原子， 原子或具有1-4个碳原子的烷氧基，n表示0,1或2，R表示具有1-12个碳原子的烷基，R'和R“各自独立地表示氢原子或具有1-4个碳原子的烷基 原子，R“”表示氢原子，具有1或2个碳原子的烷基（其可以携带至少一个选自卤素，氰基，具有至多4个碳原子的烷氧基和至多5个碳原子的烷氧基）的取代基） 具有3至18个碳原子的烷基（其携带至少一个选自卤素，氰基，具有至多4个碳原子的烷氧基和至多5个碳原子的烷氧基羰基）的取代基，具有5至8个环碳原子的环烷基，芳烷基（ 其芳基部分可以携带至少一个选自卤素，低级烷基和低级烷氧基的取代基），苯基（其可携带至少一个取代基 选自卤素，低级烷基和低级烷氧基），具有至多18个碳原子的酰基（其可被卤素和/或低级烷基取代），芳酰基（其可携带至少一个选自卤素，低级烷基和低级烷氧基 ），具有至多18个碳原子的烷基磺酰基，芳基磺酰基（其可以携带至少一个选自卤素，氨基，低级烷基和低级烷氧基的取代基）或具有至多4个碳原子的二烷基氨基，其具有杀真菌性质并且可以由 常规方法。

公开(公告)号：US3865948A

公开(公告)日：1975-02-11

申请号：US15340871

申请日：1971-06-15

申请人： MAY & BAKER LTD

发明人： EICHLER DAVID ANTHONY ,  LUCAS JOSHUA MICHAEL STUART ,  MARTIN GEORGE CHRISTOPHER JAME ,  PARNELL EDGAR WILLIAM ,  THOMPSON GARTH MOLESDALE

IPC分类号： C07C335/28 ,  C07D295/14 ,  A61K27/00

CPC分类号： C07D295/14 ,  C07C335/28

摘要： Benzene derivatives of the formula:

WHEREIN R represents an aliphatic hydrocarbon group optionally substituted by halogen or alkoxy, R1 represents hydrogen or methyl, and R2 represents hydrogen, halogen, alkyl, alkanoylamino optionally substituted by cycloalkyl of 3 to 6 carbon atoms, alkoxycarbonylamino, alkanoyl, benzoyl or N-methylmethanesulphonylamino, possess anthelmintic and anti-viral activity. New compounds within that formula also possess fungicidal properties.

摘要翻译： 苯衍生物的结构式如下：

公开(公告)号：US3655657A

公开(公告)日：1972-04-11

申请号：US8252970

申请日：1970-10-20

申请人： DU PONT

发明人： ADAMS JOHN B JR

IPC分类号： C07C335/28 ,  C07D285/16 ,  C07D93/30

CPC分类号： C07D285/16 ,  C07C335/28

摘要： A GROUP OF SUBSTITUTED 1H-2,1,4-BENZOTHIADIAZINE-3CARBAMIC ACID ESTERS ARE USEFUL FOR CONTROLLING FUNGI AND MITES. THESE COMPOUNDS CAN BE PREPARED BY THE REACTION OF AN O-NITROANILINE WITH AN ALKOXYCARBONYL ISOTHIOCYANATE FOLLOWED BY THE ALKALINE HYDROSULFITE REDUCTION OF THE INTERMEDIATE FORMED. A COMPOUND EXEMPLARY OF THE GROUP IS 1H-2,1,4-BENZOTHIADIAZINE-3-CARBAMIC ACID METHYL ESTER.