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1.发明公开公开(公告)号：US20240148614A1
公开(公告)日：2024-05-09
申请号：US18384188
申请日：2023-10-26
发明人： Sin Young KIM
IPC分类号： A61K6/56
CPC分类号： A61K6/56
摘要： Proposed are a method of preparing new biomaterials for dental pulp regeneration and a composition of new biomaterials prepared accordingly. The composition of new biomaterials prepared according to the method of preparing new biomaterials for dental pulp regeneration by mixing a first precursor containing calcium silicate-based cement (CSC) at an appropriate concentration and a second precursor containing a secretome of dental pulp-derived mesenchymal stem cells in an appropriate ratio and then drying the resulting mixture under appropriate drying conditions is characterized by further improving the osteogenic differentiation ability of dental pulp stem cells compared to existing materials while maintaining the microhardness of the composition to an appropriate standard. In addition, the composition is advantageous in that an aesthetic effect is excellent by not causing tooth discoloration.
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公开(公告)号：US20220110836A1
公开(公告)日：2022-04-14
申请号：US17557483
申请日：2021-12-21
摘要： A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
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公开(公告)号：US20240139076A1
公开(公告)日：2024-05-02
申请号：US18547042
申请日：2022-03-04
发明人： Mounir DJOUDI , Gilles RICHARD , Esther LEROUX
摘要： A dental composition including calcium silicate, calcium carbonate, and at least one pozzolanic material, which is useful to prepare a hardened dental material with improved properties. Also, a kit including the dental composition for preparing a hardened dental material, to a medical device including the kit and to the use of the hardened dental material for treating the crown of a tooth and/or the root of a tooth.
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公开(公告)号：US11484476B2
公开(公告)日：2022-11-01
申请号：US16339961
申请日：2016-10-06
发明人： Fabio Savoldi , Jukka Pekka Matinlinna , Kit Hon James Tsoi , Corrado Paganelli , Luca Visconti , Giovanni Rasia Dal Polo
摘要： A gutta-percha-silver composite with determined weight percentage and particle size, is provided. The composite exhibits electro-conductivity greater than the standard gutta-percha composites. The new material simplifies root canal treatments, shortens the times both for clinician and patients, and reduces the exposure to patients from X-rays. The material is not only electro-conductive; it is anti-bacterial, which improves the outcomes of the procedures. Also, it has improved thermal conductivity, and mechanical properties.
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公开(公告)号：US20210000989A1
公开(公告)日：2021-01-07
申请号：US17017881
申请日：2020-09-11
申请人： DENTSPLY SIRONA INC.
摘要： The present invention provides a photosensitising composition comprising a mixture of at least one surfactant at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.
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公开(公告)号：US11737956B2
公开(公告)日：2023-08-29
申请号：US16462581
申请日：2017-11-21
申请人： MARUCHI
发明人： Sung Wook Jang
IPC分类号： A61K6/00 , A61K6/853 , A61K6/54 , A61K6/76 , A61K6/869 , A61K6/73 , A61K6/69 , A61K6/56 , A61K6/80
摘要： The present invention relates to a composition of an intracanal medication agent for medicating root canals for a predetermined period of time. According to one aspect of the invention, there is provided an intracanal medication composition based on a calcium hydroxide component, comprising: calcium hydroxide or a calcium hydroxide producing component as a powder component; and at least one of diethyl sulfoxide (DMSO), N-methyl-2-pyrrolidone (NMP) and diethylene glycol monoethyl ether (DEGEE) as a liquid component.
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公开(公告)号：US11298213B2
公开(公告)日：2022-04-12
申请号：US16167950
申请日：2018-10-23
发明人： Jae Won Kim
IPC分类号： A61C8/00 , A61L24/00 , A61L27/34 , A61C13/083 , A61L27/42 , A61K6/58 , A61K6/818 , A61K6/824 , A61K6/802 , C04B41/45 , C08G77/58 , C09D183/14 , A61C5/73 , A61C13/00 , A61K6/50 , A61K6/56
摘要： A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.
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公开(公告)号：US11141353B2
公开(公告)日：2021-10-12
申请号：US15996671
申请日：2018-06-04
申请人： DENTSPLY SIRONA Inc.
摘要： A dental composition comprising a pre-reacted particulate mineral trioxide aggregate (MTA) dispersed in a polymer matrix wherein the content of MTA in the composition is in the range of 20 to 50 percent by weight based on the total weight of the composition.
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公开(公告)号：US12016938B2
公开(公告)日：2024-06-25
申请号：US17969990
申请日：2022-10-20
摘要： A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
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公开(公告)号：US20220409753A1
公开(公告)日：2022-12-29
申请号：US17894265
申请日：2022-08-24
摘要： The present invention provides a photosensitising composition comprising a mixture of: at least one surfactant; at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.
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