CONNECTION ASSEMBLY FOR A SEALED TRANSFER CONTAINER

    公开(公告)号:US20240029907A1

    公开(公告)日:2024-01-25

    申请号:US18256759

    申请日:2021-12-09

    Inventor: Jean BELIN

    CPC classification number: G21F7/005 G21F5/12

    Abstract: Connecting assembly for a fluidtight transfer container with a fluidtight transfer cell including a cell flange and a cell door, the assembly including a container flange and a container door mounted in the container flange, wherein the container flange includes a first longitudinal connection portion to the cell and a second longitudinal connection portion to a container, the first longitudinal connection portion and the second longitudinal connection portion being connected by a shoulder opposite the container door.

    Container for the aseptic transfer of a biopharmaceutical product
    4.
    发明授权
    Container for the aseptic transfer of a biopharmaceutical product 有权
    用于无菌转移生物制药产品的容器

    公开(公告)号:US09446401B2

    公开(公告)日:2016-09-20

    申请号:US14234815

    申请日:2012-07-12

    Applicant: Gaelle Nodin

    Inventor: Gaelle Nodin

    Abstract: A container for ensuring the transport and the aseptic transfer of a biopharmaceutical product from or to a closed chamber provided with a leaktight joining device, includes: an annular flange delimiting an opening, a removable cover, built-in elements for locking/unlocking the removable cover and a peripheral envelope. The built-in locking/unlocking elements include a built-in functional locking/unlocking arrangement formed by a through-housing formed in the annular flange and a blind housing formed in the removable cover, and by a pin at an inner radial position and a pin at an outer radial position. The container is capable of being in an initial locking position, in an intermediate unlocking position and in a final locking position owing to the displacements of the pin at an inner radial position and the pin at an outer radial position in the blind hole of the removable cover and in the through-housing of the annular flange.

    Abstract translation: 一种用于确保生物制药产品从设置有密封接合装置的封闭室输送和无菌转运的容器包括:限定开口的环形凸缘,可移除盖,用于锁定/解锁可拆卸 封面和外围信封。 内置的锁定/解锁元件包括由形成在环形凸缘中的通孔形成的内置功能锁定/解锁装置和形成在可移除盖中的盲壳以及在内部径向位置处的销和 销在外径向位置。 容器能够处于初始锁定位置,处于中间解锁位置并处于最终锁定位置,这是由于销在内部径向位置处的位移,并且销处于可拆卸的盲孔中的外部径向位置 盖和环形凸缘的通孔中。

    Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container
    5.
    发明授权
    Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container 有权
    用于在室和容器之间无菌转移生物药物产品的泄漏接合装置

    公开(公告)号:US09440229B2

    公开(公告)日:2016-09-13

    申请号:US14234788

    申请日:2012-07-12

    CPC classification number: B01L1/02 C12M37/04 G21F7/005

    Abstract: A leaktight joining device for ensuring the aseptic transfer of a biopharmaceutical product between a chamber equipped with a removable door and a container equipped with a removable cover, includes: stationary temporary flanging elements, stationary unlocking elements capable of changing the container from an initial locking position to an intermediate unlocking position so as to ensure an aseptic communication between the container and the chamber, stationary locking element capable of changing the container from the intermediate locking position to a final locking position, an annular functional ring gear capable of actuating the stationary unlocking elements and the stationary locking elements of the container. The stationary temporary flanging elements, the stationary unlocking elements, and the stationary locking elements are mechanically linked to the annular functional ring gear and arranged so that the unidirectional rotation of the annular functional ring gear about the geometric axis of rotation successively drives the actuation thereof.

    Abstract translation: 一种用于确保生物制药产品在装有可拆卸门的室与装有可移除盖的容器之间无菌转移的密封接合装置包括:固定的临时折边元件,能够将容器从初始锁定位置改变的固定解锁元件 以确保容器和腔室之间的无菌连通,能够将容器从中间锁定位置改变到最终锁定位置的固定锁定元件,能够致动固定解锁元件的环形功能性环形齿轮 和容器的固定锁定元件。 固定的临时折边元件,固定解锁元件和固定锁定元件机械地连接到环形功能性环形齿轮并且被布置成使得环形功能性环形齿轮围绕旋转几何轴线的单向旋转连续地驱动其致动。

    Particle beam irradiation chamber
    6.
    发明授权
    Particle beam irradiation chamber 有权
    粒子束照射室

    公开(公告)号:US09399147B2

    公开(公告)日:2016-07-26

    申请号:US14772696

    申请日:2014-03-20

    Abstract: A particle beam irradiation chamber in which a passage having a first opening part at a side of an inner wall and a second opening part at a side of an outer wall is provided and which has an isocenter inside the chamber, wherein a first line segment which connects the center of the first opening part and the center of the second opening part passes inside the passage, an angle, which is formed by a second segment, which connects the center of the first opening part and the isocenter and the first line segment, is smaller than 180 degrees, and a width of the passage is narrower than a width of opening of the first opening part.

    Abstract translation: 一种粒子束照射室,其中设置有在内壁的一侧具有第一开口部分和在外壁一侧的第二开口部分的通道,并且在腔室内具有等角点,其中第一线段 连接第一开口部的中心并且第二开口部的中心在通路内通过由连接第一开口部的中心与等角点与第一线段的第二部分形成的角度, 小于180度,通道的宽度比第一开口部的开口宽度窄。

    PARTICLE BEAM IRRADIATION ROOM AND PARTICLE BEAM THERAPY SYSTEM
    7.
    发明申请
    PARTICLE BEAM IRRADIATION ROOM AND PARTICLE BEAM THERAPY SYSTEM 审中-公开
    颗粒光束辐射室和颗粒束治疗系统

    公开(公告)号:US20160051844A1

    公开(公告)日:2016-02-25

    申请号:US14781092

    申请日:2013-04-01

    Abstract: The particle beam irradiation room of the invention includes: an irradiation execution room in which a patient table having a detachable-attachable top board and an actuation device for actuating the top board is mounted, and that is surrounded by a shielding wall; a passage formed in the shielding wall on its side where a pre-room for positioning the patient relative to the top board is located, in a form that allows the patient positioned relative to the top board to pass straight to the irradiation execution room by a transport apparatus; and a shielding door at the irradiation-room entrance located on a side of the passage toward the pre-room, for shielding against a leakage radiation at the radiation of the particle beam so that the leakage radiation is kept at a management value or less.

    Abstract translation: 本发明的粒子束照射室包括:照射执行室,其中安装有具有可拆卸顶板的患者台和用于致动顶板的致动装置,并且被遮蔽壁包围; 形成在其侧面上的屏蔽壁中的通道,其中用于将患者相对于顶板定位的房间以允许患者相对于顶板定位的形式通过直接通过照射执行室通过 运输设备 以及位于通向前室的通道侧的照射室入口处的屏蔽门,用于防止在粒子束的辐射下的泄漏辐射,使得泄漏辐射保持在管理值以下。

    PARTICLE BEAM IRRADIATION CHAMBER
    8.
    发明申请
    PARTICLE BEAM IRRADIATION CHAMBER 有权
    颗粒光束辐照室

    公开(公告)号:US20160016011A1

    公开(公告)日:2016-01-21

    申请号:US14772696

    申请日:2014-03-20

    Abstract: A particle beam irradiation chamber in which a passage having a first opening part at a side of an inner wall and a second opening part at a side of an outer wall is provided and which has an isocenter inside the chamber, wherein a first line segment which connects the center of the first opening part and the center of the second opening part passes inside the passage, an angle, which is formed by a second segment, which connects the center of the first opening part and the isocenter and the first line segment, is smaller than 180 degrees, and a width of the passage is narrower than a width of opening of the first opening part.

    Abstract translation: 一种粒子束照射室,其中设置有在内壁的一侧具有第一开口部分和在外壁一侧的第二开口部分的通道,并且在腔室内具有等角点,其中第一线段 连接第一开口部的中心并且第二开口部的中心在通路内通过由连接第一开口部的中心与等角点与第一线段的第二部分形成的角度, 小于180度,通道的宽度比第一开口部的开口宽度窄。

    Handling and Confinement Hood, Application to Handling Holders of Samples of Nuclear Materials Such as Nuclear Fuels
    9.
    发明申请
    Handling and Confinement Hood, Application to Handling Holders of Samples of Nuclear Materials Such as Nuclear Fuels 有权
    处理和限制罩,应用于核材料样品的处理持有人,如核燃料

    公开(公告)号:US20140301521A1

    公开(公告)日:2014-10-09

    申请号:US14249126

    申请日:2014-04-09

    CPC classification number: G21F5/065 G21F5/14 G21F7/005 G21F7/06

    Abstract: The present invention concerns a hood for handling and confinement of at least two objects of slender shape, including an external enclosure and internal enclosures inside the external enclosure and at least one motor fixed above an internal enclosure and inside a barrel, the motor(s) being adapted to rotate the screw of the screw-nut mechanism of each internal enclosure and therefore the nut over a stroke A, and first and second mechanical control means, arranged in part above the cover of the external enclosure, respectively for manually guiding the internal enclosures in translation over a stroke A0 and manually pivoting the barrel in order to bring a holding member of one of the internal enclosures opposite the opening in the bottom of the external enclosure. Application to the handling and confinement of nuclear material sample holders.

    Abstract translation: 本发明涉及用于处理和限制细长形状的至少两个物体的罩,包括外部外壳和内部外壳内部的内部外壳以及固定在内部外壳和枪管内部的至少一个马达, 适于旋转每个内部壳体的螺母 - 螺母机构的螺钉,并因此旋转螺母在行程A上,以及第一和第二机械控制装置,分别设置在外部外壳的盖的上方,用于手动地引导内部 外壳以行程A0平移并且手动地旋转镜筒,以使内部外壳中的一个的保持构件与外部外壳的底部中的开口相对。 适用于处理和限制核材料样品持有人。

    HOUSING FOR TIGHT CONNECTION DEVICE AND ASEPTIC TRANSFER DEVICE
    10.
    发明申请
    HOUSING FOR TIGHT CONNECTION DEVICE AND ASEPTIC TRANSFER DEVICE 有权
    用于紧密连接装置和非传送装置的壳体

    公开(公告)号:US20120292311A1

    公开(公告)日:2012-11-22

    申请号:US13511210

    申请日:2010-11-23

    Abstract: The invention relates to a housing (1) that is especially designed to be associated with a device for a tight connection to a second housing (2), said first housing comprising a structure including a wall (3) defining a space (1a), an opening (4) defined by a flange (5) that can be hermetically applied to a second flange (9) of the second housing (2), holding means that can keep the first flange and the second flange (9) applied to each other, a door (6) supported by carrying means (11a), the door leaf (6v) being mobile in such a way as to be closed or open and having an outer face (6a) that can ensure the hermetic application of a second door (10) of the second housing (2), fixing means for holding the leaves (6v, 1 Ov) against each other, displacement manoeuvring means (11b), and means for controlling the displacement manoeuvring means (11b), and, when the leaf (6v) is open, an inlet/outlet space (13a) in/of the inner space (1a) forming part of a communication space (13) between the two housings (1, 2), wherein the carrying means (11a) and the displacement manoeuvring means (11b) for the door (6) are arranged in such a way that, when the leaf (6v) is open, it extends essentially past the limit (13b, 13c) of the inlet/outlet space (13a), a distancing space (12) being thus created between the inlet/outlet space (13a) and the leaf (6v) in the open state.

    Abstract translation: 本发明涉及一种特别设计成与用于紧密连接到第二壳体(2)的装置相关联的壳体(1),所述第一壳体包括包括限定空间(1a)的壁(3)的结构, 由法兰(5)限定的能够气密地施加到第二壳体(2)的第二凸缘(9)的开口(4),保持装置可以将第一凸缘和第二凸缘(9)保持在每个 另一方面,由承载装置(11a)支撑的门(6),门扇叶片(6v)以可关闭或打开的方式移动,并且具有可以确保第二个密封件的密封应用的外表面(6a) 第二壳体(2)的门(10),用于将叶片(6v,110v)相对于彼此保持的固定装置,位移操纵装置(11b)和用于控制排量操纵装置(11b)的装置,以及当 叶片(6v)打开,内部空间(1a)中的入口/出口空间(13a)形成在通风空间(13)的一部分之间, 两个壳体(1,2),其中用于门(6)的运送装置(11a)和排量操纵装置(11b)以这样的方式布置,使得当叶片(6v)打开时,其基本上延伸 入口/出口空间(13a)的极限(13b,13c),在打开状态下在入口/出口空间(13a)和叶子(6v)之间形成的间隔空间(12)。

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