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    Optical and chemical analytical systems and methods
    2.
    发明授权
    Optical and chemical analytical systems and methods 有权
    光学和化学分析系统和方法

    公开(公告)号：US09562862B2

    公开(公告)日：2017-02-07

    申请号：US14507637

    申请日：2014-10-06

    申请人： H2Optx Inc.

    发明人： Rudy Hofmeister ,  Scott Tandy ,  Donald Ice

    IPC分类号： G01N21/00 ,  G01N21/65 ,  G01N21/64

    CPC分类号： G01N21/65 ,  G01N21/64 ,  G01N21/6456 ,  G01N2201/06113 ,  G01N2201/06146

    摘要： Optical and chemical analytical systems and methods are provided herein. In one embodiment, a method includes exposing a mixture sample to electromagnetic radiation, the mixture sample including analytes, detecting responsiveness of one or more of the analytes to the electromagnetic radiation, calculating average responsiveness of the one or more of the analytes, and calculating a concentration of the one or more of the analytes in the mixture sample using the average responsiveness.

    摘要翻译： 本文提供光学和化学分析系统和方法。 在一个实施方案中，一种方法包括将混合物样品暴露于电磁辐射，混合物样品包括分析物，检测一种或多种分析物对电磁辐射的响应性，计算一种或多种分析物的平均响应性，并计算 使用平均响应度浓缩混合物样品中一种或多种分析物。

    SYSTEMS AND METHODS FOR DIAGNOSIS OF EPITHELIAL LESIONS
    3.
    发明申请
    SYSTEMS AND METHODS FOR DIAGNOSIS OF EPITHELIAL LESIONS 审中-公开
    用于诊断上皮层的系统和方法

    公开(公告)号：US20160146730A1

    公开(公告)日：2016-05-26

    申请号：US14939044

    申请日：2015-11-12

    申请人： Board of Regents, the University of Texas System

    发明人： James W. TUNNELL

    IPC分类号： G01N21/47 ,  G01N21/64 ,  G01N21/65 ,  G01J3/42

    CPC分类号： G01N21/474 ,  A61B5/0075 ,  A61B5/444 ,  G01J3/42 ,  G01N21/31 ,  G01N21/6486 ,  G01N21/65 ,  G01N2021/1736 ,  G01N2021/174 ,  G01N2201/0221 ,  G01N2201/06113 ,  G01N2201/06146 ,  G01N2201/0833

    摘要： Systems comprising an optical fiber switch connected to a light source and an optical fiber probe, the optical fiber probe comprising a first optical fiber connected to the optical fiber switch and a second optical fiber connected to a spectrophotometer. Methods for determining one or more tissue parameters comprising: emitting light from a first optical fiber into a tissue; collecting the light reemitted from the tissue with a second optical fiber; generating a spectra of the light reemitted from the tissue with a spectrophotometer; and utilizing a look-up table based algorithm to determine one or more tissue parameters, wherein the lookup-table based algorithm comprises the steps of: generating a look-up table by measuring the functional form of a reflectance measured by the spectrophotometer using one or more calibration standards with known optical properties; and implementing an iterative fitting routine based on the lookup-table.

    摘要翻译： 包括连接到光源的光纤开关和光纤探针的系统，所述光纤探针包括连接到光纤开关的第一光纤和连接到分光光度计的第二光纤。 用于确定一个或多个组织参数的方法，包括：将光从第一光纤发射到组织中; 用第二光纤收集从组织再发射的光; 用分光光度计产生从组织再发射的光的光谱; 以及利用基于查找表的算法来确定一个或多个组织参数，其中所述基于查找表的算法包括以下步骤：通过测量由所述分光光度计测量的反射率的函数形式来生成查找表，使用一个或多个 具有已知光学性能的更多校准标准; 并且基于查找表来实现迭代拟合例程。

    GEMSTONE SPARKLE ANALYSIS
    4.
    发明申请
    GEMSTONE SPARKLE ANALYSIS 审中-公开
    GEMSTONE SPARKLE分析

    公开(公告)号：US20160103078A1

    公开(公告)日：2016-04-14

    申请号：US14974425

    申请日：2015-12-18

    申请人： De Beers UK Ltd.

    发明人： James Gordon Charters SMITH

    IPC分类号： G01N21/87 ,  G01N21/55

    CPC分类号： G01N21/87 ,  G01N21/55 ,  G01N33/381 ,  G01N2201/06146 ,  G01N2201/0634

    摘要： A system is described for obtaining images of a gemstone, and performing quantitative analysis on the images to obtain measures of properties of the gemstone. The system comprises a support structure for supporting the gemstone at an observation position. An illumination structure is arranged to illuminate the gemstone. The illumination structure comprises a plurality of radially dispersed directional light sources directed towards the observation position, the support structure and illumination system being rotatable relative to one another around a rotation axis so that the gemstone can be illuminated by one or more of the directional light sources at each of a plurality of rotational positions, the axis of rotation being normal to a selected facet of the gemstone. An imaging device is directed towards the gemstone for obtaining images of the gemstone at each of the rotational positions, the imaging device having an imaging axis parallel to or coincident with the axis of rotation. An image processor is provided for identifying sparkle regions in the images corresponding to reflections from individual light sources by individual facets and providing a quantitative measure of the gemstone on the basis of properties of the sparkle regions.

    摘要翻译： 描述了一种用于获得宝石图像的系统，并对图像进行定量分析以获得宝石特性的度量。 该系统包括用于在观察位置支撑宝石的支撑结构。 布置照明结构来照亮宝石。 照明结构包括指向观察位置的多个径向分散的定向光源，支撑结构和照明系统可围绕旋转轴线相对于彼此旋转，使得宝石能够被一个或多个定向光源 在多个旋转位置中的每一个处，所述旋转轴线垂直于所述宝石的选定小面。 成像装置被引向宝石，以在每个旋转位置获得宝石的图像，成像装置具有与旋转轴线平行或重合的成像轴。 提供一种图像处理器，用于识别对应于各个光源的各个光源的反射的图像中的闪耀区域，并且基于闪光区域的特性提供宝石的定量测量。

    GEMSTONE SPARKLE ANALYSIS
    5.
    发明申请
    GEMSTONE SPARKLE ANALYSIS 有权
    GEMSTONE SPARKLE分析

    公开(公告)号：US20130016210A1

    公开(公告)日：2013-01-17

    申请号：US13575067

    申请日：2011-01-26

    申请人： James Gordon Charters Smith

    发明人： James Gordon Charters Smith

    IPC分类号： H04N7/18

    CPC分类号： G01N21/87 ,  G01N21/55 ,  G01N33/381 ,  G01N2201/06146 ,  G01N2201/0634

    摘要： A system is described for obtaining images of a gemstone, and performing quantitative analysis on the images to obtain measures of properties of the gemstone. The system comprises a support structure for supporting the gemstone at an observation position. An illumination structure is arranged to illuminate the gemstone. The illumination structure comprises a plurality of radially dispersed directional light sources directed towards the observation position, the support structure and illumination system being rotatable relative to one another around a rotation axis so that the gemstone can be illuminated by one or more of the directional light sources at each of a plurality of rotational positions, the axis of rotation being normal to a selected facet of the gemstone. An imaging device is directed towards the gemstone for obtaining images of the gemstone at each of the rotational positions, the imaging device having an imaging axis parallel to or coincident with the axis of rotation. An image processor is provided for identifying sparkle regions in the images corresponding to reflections from individual light sources by individual facets and providing a quantitative measure of the gemstone on the basis of porperties of the sparkle regions.

    摘要翻译： 描述了一种用于获得宝石图像的系统，并对图像进行定量分析以获得宝石特性的度量。 该系统包括用于在观察位置支撑宝石的支撑结构。 布置照明结构来照亮宝石。 照明结构包括指向观察位置的多个径向分散的定向光源，支撑结构和照明系统可围绕旋转轴线相对于彼此旋转，使得宝石能够被一个或多个定向光源 在多个旋转位置中的每一个处，所述旋转轴线垂直于所述宝石的选定小面。 成像装置被引向宝石，以在每个旋转位置获得宝石的图像，成像装置具有与旋转轴线平行或重合的成像轴。 提供图像处理器，用于识别对应于各个光源的各个光源的反射的图像中的闪耀区域，并且基于闪光区域的特征提供宝石的定量测量。

    Device and method for measuring light diffusely reflected from a nonuniform specimen
    6.
    发明授权
    Device and method for measuring light diffusely reflected from a nonuniform specimen 失效
    用于测量从不均匀样品漫反射的光的装置和方法

    公开(公告)号：US4755058A

    公开(公告)日：1988-07-05

    申请号：US866730

    申请日：1986-05-27

    申请人： Gerald H. Shaffer

    发明人： Gerald H. Shaffer

    IPC分类号： G01N21/47 ,  G01N21/86 ,  G01N21/31

    CPC分类号： G01N21/8483 ,  G01N21/474 ,  G01N2021/478 ,  G01N2201/06146 ,  G01N2201/0621 ,  G01N2201/0696

    摘要： A device for making accurate, reproducible light reflectance measurements on an optically nonuniform specimen comprises means for holding the specimen in a fixed position. In one embodiment the specimen is illuminated by light sources that are arranged at acute angles relative to the specimen and (360.degree./N.+-.1.degree.) apart in azimuth, where N=the total number of light sources. The light sources are sequentially energized and deenergized to illuminate the specimen. A light detector receives light reflecting from the surface and generates an electrical signal, which is subsequently processed. In another embodiment the light sources are arranged in pairs in which the two light sources in a pair are simultaneously energized and deenergized and the pairs are sequentially energized and deenergized. A method for measuring reflected light is also provided. The device and method are useful for making biochemical assays with reagent test strips by measuring the tone of coloration of the strips after treatment with a target substance being examined.

    摘要翻译： 用于在光学不均匀样品上进行准确，可再现的光反射测量的装置包括用于将样品保持在固定位置的装置。 在一个实施例中，样品被相对于试样以锐角排列并且在方位角（360°/ N +/- 1°）分开的光源照射，其中N =光源的总数。 光源依次通电并断电以照射样品。 光检测器接收从表面反射的光并产生随后处理的电信号。 在另一个实施例中，光源成对地布置，其中一对中的两个光源同时通电并断电，并且对依次通电并断电。 还提供了一种用于测量反射光的方法。 该装置和方法可用于通过用待检测的目标物质测量处理后条带的着色色调来对试剂测试条进行生化测定。

    OPTICAL AND CHEMICAL ANALYTICAL SYSTEMS AND METHODS
    10.
    发明申请
    OPTICAL AND CHEMICAL ANALYTICAL SYSTEMS AND METHODS 有权
    光学和化学分析系统和方法

    公开(公告)号：US20160069805A1

    公开(公告)日：2016-03-10

    申请号：US14507637

    申请日：2014-10-06

    申请人： H2Optx Inc.

    发明人： Rudy Hofmeister ,  Scott Tandy ,  Donald Ice

    IPC分类号： G01N21/64 ,  G01J3/44

    CPC分类号： G01N21/65 ,  G01N21/64 ,  G01N21/6456 ,  G01N2201/06113 ,  G01N2201/06146

    摘要： Optical and chemical analytical systems and methods are provided herein. In one embodiment, a method includes exposing a mixture sample to electromagnetic radiation, the mixture sample including analytes, detecting responsiveness of one or more of the analytes to the electromagnetic radiation, calculating average responsiveness of the one or more of the analytes, and calculating a concentration of the one or more of the analytes in the mixture sample using the average responsiveness.

    摘要翻译： 本文提供光学和化学分析系统和方法。 在一个实施方案中，一种方法包括将混合物样品暴露于电磁辐射，混合物样品包括分析物，检测一种或多种分析物对电磁辐射的响应性，计算一种或多种分析物的平均响应性，并计算 使用平均响应度浓缩混合物样品中一种或多种分析物。