公开(公告)号：US20240158639A1

公开(公告)日：2024-05-16

申请号：US18546342

申请日：2022-03-21

Applicant: ICROM Srl

Inventor： Daniele De Zani ,  Simone Parma

IPC: C09B23/08 ,  C07D209/60 ,  C09B67/42 ,  C09B67/54 ,  G01N30/74 ,  G01N30/88

CPC classification number: C09B23/083 ,  C07D209/60 ,  C09B67/0092 ,  C09B67/0096 ,  G01N30/74 ,  G01N30/88 ,  G01N2030/027

Abstract: The present invention relates to a process for the preparation, also on an industrial scale, of indocyanine green of formula (I) (ICG, 1 H-benz[e]indole, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-di-methyl-3-(4-sulfobutyl) hydroxide, inner salt, sodium salt, CAS RN 3599-32-4) with a total impurity content

公开(公告)号：US20180346728A1

公开(公告)日：2018-12-06

申请号：US15780555

申请日：2016-11-29

Applicant: DISHMAN PHARMACEUTICALS AND CHEMICALS LIMITED

Inventor： Janmejay Rajnikant Vyas ,  Himani Dhotre ,  Narasimha Sarma ,  Babulal R. Patel ,  Dinesh Kumar Sharma ,  Dilip N. Patel ,  Ashish A. Soni

IPC: C09B23/08 ,  C09B67/42 ,  C09B67/54

CPC classification number: C09B23/086 ,  A61K49/0034 ,  C07D209/60 ,  C09B67/0092 ,  C09B67/0096

Abstract: The present invention involves an improved process for the preparation of Indocyanine green of Formula (I) having high purity of about 99%, wherein the process comprises steps of reacting 1,1,2-trimethyl-1H-benzo[e]indole with 1,4-butane sulfone in boiling solvent to give 4-(1,1,2-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate. Followed by reacting 4-(1,1,2-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate of Formula (IV) and N-phenyl-N-((1E,3E,5E)-5-(phenylimino)penta-1,3-dienyl)acetamide of formula (V) in presence of sodium acetate and alcohol; and extracting the title compound formula (I) with an ester solvent.

公开(公告)号：US20180065073A1

公开(公告)日：2018-03-08

申请号：US15682842

申请日：2017-08-22

Applicant: The Procter & Gamble Company

Inventor： Geoffrey Marc Wise ,  Ioannis Constantine Constantinides

IPC: B01D47/02 ,  B01D47/04 ,  B01D9/00 ,  C07B63/02 ,  C09B67/02 ,  C09B67/54

CPC classification number: B01D47/021 ,  B01D9/0036 ,  B01D9/0063 ,  B01D19/0431 ,  B01D19/0445 ,  B01D47/04 ,  C01P2004/61 ,  C01P2004/62 ,  C07B63/02 ,  C09B41/006 ,  C09B67/0092 ,  C09B67/0096 ,  C09B67/0097

Abstract: The invention relates to a process of creating particles of controlled size by creating them in the interstitial regions in a continuous liquid phase that contains a second, inert gas phase at high volume fraction; namely a foam. The second phase creates a physical barrier that limits the aggregation of formed particles beyond the size of the narrow interstitial regions occupied by the continuous phase. This technique is useful when the particles normally create large aggregates due to the fast nature of the reaction and the strong attractions between the formed particles, and for enhancing the deposition of high-value materials by connecting them to coacervates of controlled size.

公开(公告)号：US20170342272A1

公开(公告)日：2017-11-30

申请号：US15535966

申请日：2015-12-15

Applicant: M. TECHNIQUE CO., LTD.

Inventor： Masakazu ENOMURA ,  Daisuke HONDA

IPC: C09B67/22 ,  C09B67/42

CPC classification number: C09B67/0035 ,  B01J19/1887 ,  C07B61/00 ,  C07D487/22 ,  C09B67/0092

Abstract: The purpose of the present invention is to provide: composite phthalocyanine microparticles of a nano-order level, preferably on the order of 100 nm, that are optimal as a coloring material; and a method for producing the same. Provided is a method for producing composite phthalocyanine microparticles, the method being characterized by including a step (1) for preparing a dissolved solution by dissolving at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine as raw materials in a first solvent, a step (2) for precipitating composite phthalocyanine by mixing the dissolved solution obtained in step (1) with a second solvent that serves as a poor solvent of the abovementioned raw materials, and a step (3) for causing an organic solvent to act on the composite phthalocyanine obtained in step (2). Also provided are composite phthalocyanine microparticles containing at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine, the composite phthalocyanine microparticles having an aspect ratio of 1.1-2.5 and a particle size of 5-100 nm.

公开(公告)号：US09540600B2

公开(公告)日：2017-01-10

申请号：US13874548

申请日：2013-05-01

Applicant: The Procter & Gamble Company

Inventor： Patrick Christopher Stenger ,  Gregory Scot Miracle ,  Andrew Philip Moon ,  Michael McDonnell ,  Gregory Edward Fernandes ,  Dominick Joseph Valenti

IPC: C11D3/12 ,  C11D3/40 ,  C11D3/42 ,  C11D3/386 ,  C11D17/06 ,  C09B67/08 ,  C09B67/42 ,  C11D17/00

CPC classification number: C11D3/42 ,  C09B67/0007 ,  C09B67/0092 ,  C09B67/0095 ,  C11D3/126 ,  C11D3/40 ,  C11D17/0034

Abstract: A laundry detergent composition having a particle, wherein the particle has: (a) hueing agent, wherein the hueing agent has the following structure: wherein: R1 and R2 are independently selected from the group consisting of: H; alkyl; alkoxy; alkyleneoxy; alkyl capped alkyleneoxy; urea; and amido; R3 is a substituted aryl group; X is a substituted group comprising sulfonamide moiety and optionally an alkyl and/or aryl moiety, and wherein the substituent group comprises at least one alkyleneoxy chain that comprises an average molar distribution of at least four alkyleneoxy moieties; (b) clay; and (c) another detergent ingredient.

Abstract translation: 一种具有颗粒的衣物洗涤剂组合物，其中所述颗粒具有：（a）调色剂，其中所述调色剂具有以下结构：其中：R 1和R 2独立地选自：H; 烷基; 烷氧基 亚烷氧基; 烷基封端的亚烷基氧基; 尿素 和amido; R3是取代的芳基; X是包含磺酰胺部分和任选的烷基和/或芳基部分的取代基，并且其中所述取代基包含至少一个包含至少四个亚烷氧基部分的平均摩尔分布的亚烷基氧基链; （b）粘土; 和（c）另一种洗涤剂成分。

公开(公告)号：US08618161B2

公开(公告)日：2013-12-31

申请号：US13026690

申请日：2011-02-14

Applicant: Joe Y. L. Lam ,  Steven M. Menchen ,  Ruiming Zou ,  Scott C. Benson

Inventor： Joe Y. L. Lam ,  Steven M. Menchen ,  Ruiming Zou ,  Scott C. Benson

IPC: A61K31/352 ,  C07D311/92

CPC classification number: C09K11/025 ,  C07D311/80 ,  C09B11/24 ,  C09B67/0092 ,  C09B67/0097 ,  C09B69/103 ,  C09K11/06 ,  C09K2211/1088 ,  C09K2211/1416 ,  C09K2211/145

Abstract: Fluorescent polymeric materials are disclosed comprising a polymeric particle and one or more lipid soluble rhodamine dyes, comprising the following core structure: wherein R11 and R15 are each H or are each F or Cl; R12, R13, and R14 are each H or are each F or Cl; and wherein at least one of R3′, R3″, R6′ and R6′ is a (C4-C20) alkyl. The materials are especially useful in the preparation of multicolored microparticles, especially multicolored polystyrene microparticle, for use in the multiplexed analysis of a plurality of analytes in a single sample. When excited by a light source, the materials give off a unique emission based on the nature, concentration and ratio of the dyes therein. Methods of preparing and using said materials are also disclosed.

Abstract translation: 公开了包含聚合物颗粒和一种或多种脂溶性罗丹明染料的荧光聚合物材料，其包含以下核心结构：其中R 11和R 15各自为H或各自为F或Cl; R 12，R 13和R 14各自为H或分别为F或Cl; 并且其中R 3'，R 3“，R 6'和R 6'中的至少一个是（C 4 -C 20）烷基。 这些材料在制备多彩色微粒，特别是多色聚苯乙烯微粒中是特别有用的，用于在单个样品中多个分析物的多重分析。 当被光源激发时，材料基于其中染料的性质，浓度和比例发出独特的发射。 还公开了制备和使用所述材料的方法。

公开(公告)号：US20130220180A1

公开(公告)日：2013-08-29

申请号：US13883692

申请日：2011-05-20

Applicant: Masaki Maekawa ,  Kaeko Araki ,  Hideyuki Oka ,  Daisuke Honda ,  Masakazu Enomura

Inventor： Masaki Maekawa ,  Kaeko Araki ,  Hideyuki Oka ,  Daisuke Honda ,  Masakazu Enomura

IPC: C09C1/62

CPC classification number: C07F3/06 ,  B01D11/0269 ,  B01F3/0861 ,  B82Y30/00 ,  C01P2004/64 ,  C01P2004/82 ,  C07F1/08 ,  C09B67/0017 ,  C09B67/0019 ,  C09B67/0026 ,  C09B67/0035 ,  C09B67/0092 ,  C09C1/0081 ,  C09C1/04 ,  C09C1/627

Abstract: The problem addressed by the present invention is to provide; solid solution pigment nanoparticles having a homogeneous solid solution ratio; a method for producing solid solution pigment nanoparticles having a homogeneous solid solution ratio in each primary particle; and a method for controlling the solid solution ratio of solid solution pigment nanoparticles. The solid solution pigment nanoparticles are prepared by precipitating at least two types of pigment by mixing a pigment precipitation solvent and; at least one type of pigment solution wherein at least two types of pigment are dissolved in a solvent: or at least two types of pigment solution wherein at least one type of pigment is dissolved in a solvent. The solid solution pigment nanoparticles are wherein the solid solution ratio of the at least two types of pigment in the primary particles of the precipitated solid solution pigment nanoparticles with respect to the ratio of the at least two types of pigment in the pigment solution mixed with the pigment precipitation solvent having a precision within 25%.

Abstract translation: 本发明提出的问题在于： 具有均匀固溶比的固溶颜料纳米粒子; 一种在一次粒子中具有均匀固溶比的固溶颜料纳米粒子的制造方法; 以及控制固溶颜料纳米粒子的固溶比的方法。 固溶颜料纳米粒子是通过混合颜料沉淀溶剂和至少两种颜料沉淀来制备的; 至少一种类型的颜料溶液，其中至少两种类型的颜料溶解在溶剂中：或至少两种类型的颜料溶液，其中至少一种类型的颜料溶解在溶剂中。 固溶颜料纳米粒子，其中沉淀的固溶颜料纳米颗粒的初级颗粒中的至少两种类型的颜料的固溶比相对于颜料溶液中的至少两种类型的颜料与 颜料沉淀溶剂的精度在25％以内。

公开(公告)号：US07939587B2

公开(公告)日：2011-05-10

申请号：US12438615

申请日：2007-08-08

Applicant: Johannes Loebel ,  Peter Madla ,  Jacques Mercy ,  Claudia Sierakowski

Inventor： Johannes Loebel ,  Peter Madla ,  Jacques Mercy ,  Claudia Sierakowski

IPC: C08K5/34 ,  C08G67/02

CPC classification number: C09B67/0011 ,  C09B67/0063 ,  C09B67/0092

Abstract: Solid pigment preparations comprise as essential constituents (A) at least one organic pigment, (B) at least one polyisobutene derivative having at least one nitrogenous end group and (C) at least one nonionic surface-active additive.

Abstract translation: 固体颜料制剂包含至少一种有机颜料，（B）至少一种具有至少一个含氮端基的至少一种聚异丁烯衍生物和（C）至少一种非离子表面活性添加剂作为必要组分（A）。

公开(公告)号：US20100288162A1

公开(公告)日：2010-11-18

申请号：US12467769

申请日：2009-05-18

Applicant: Adela GOREDEMA ,  C. Geoffrey ALLEN ,  Caroline M. TUREK ,  Christopher WAGNER ,  Raymond WONG ,  Mihaela Maria BIRAU ,  Sheau Van KAO

Inventor： Adela GOREDEMA ,  C. Geoffrey ALLEN ,  Caroline M. TUREK ,  Christopher WAGNER ,  Raymond WONG ,  Mihaela Maria BIRAU ,  Sheau Van KAO

IPC: C09D11/02 ,  C09D11/10 ,  C09D11/12

CPC classification number: C09D11/34 ,  C09B67/0069 ,  C09B67/0092 ,  C09D11/326

Abstract: A pigmented phase change ink composition comprising an ink vehicle, a dispersant, and pigment particles wherein the dispersant is a chemical compound of formula: wherein R1 is an alkyl group, aryl group, alkylaryl group or arylalkyl group with at least 23 carbon atoms, R2 is an alkylene group, arylene group, alkylarylene group or arylalkylene group with at least 2 carbons and X is a quaternary ammonium salt. The ink can be resistant to substantial aggregation and settling of the pigment particles in the melt and even when exposed to freeze thaw cycles.

Abstract translation: 一种着色相变油墨组合物，其包含油墨载体，分散剂和颜料颗粒，其中所述分散剂是下式的化合物：其中R 1是具有至少23个碳原子的烷基，芳基，烷基芳基或芳烷基，R 2 是具有至少2个碳的亚烷基，亚芳基，烷基亚芳基或芳基亚烷基，X是季铵盐。 油墨可以抵抗颜料颗粒在熔体中的显着聚集和沉降，甚至在暴露于冻融循环时也是如此。

公开(公告)号：US20070173547A1

公开(公告)日：2007-07-26

申请号：US10587562

申请日：2005-02-02

Applicant: Jesper Feldthusen Jensen

Inventor： Jesper Feldthusen Jensen

IPC: A61K31/22 ,  A61K31/12 ,  A61K31/015

CPC classification number: C09B67/0092 ,  A23K20/147 ,  A23K20/163 ,  A23K20/179 ,  A23K40/10 ,  A23K50/75 ,  A23K50/80 ,  A23L5/44 ,  A61K31/015 ,  C07C403/24 ,  C09B67/0002

Abstract: The invention relates to a method for producing dry powders of one or several carotenoids, said method being characterised in that a) one or several carotenoids are suspended in an aqueous molecularly dispersed or colloidally dispersed solution of a mixture consisting of trehalose and at least one protein-containing protective colloid and b) the obtained suspension is transformed into a dry powder by separation of water and, optionally, additionally used solvents and by subsequent drying, optionally in the presence of a coating material.

Abstract translation: 本发明涉及一种生产一种或几种类胡萝卜素的干粉的方法，所述方法的特征在于：a）将一种或几种类胡萝卜素悬浮在由海藻糖和至少一种蛋白质组成的混合物的分子分散或胶体分散的水溶液中 并且b）通过分离水和任选的另外使用的溶剂将所得到的悬浮液转变成干燥粉末，随后通过随后的干燥，任选地在涂料存在下转化成干粉。