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    PATCH PACKAGE STRUCTURE
    3.
    发明申请
    PATCH PACKAGE STRUCTURE 失效
    PATCH包装结构

    公开(公告)号：US20090011159A1

    公开(公告)日：2009-01-08

    申请号：US12167085

    申请日：2008-07-02

    申请人： Katsuhiro Okada ,  Yoshihiro Iwao ,  Kensuke Matsuoka

    发明人： Katsuhiro Okada ,  Yoshihiro Iwao ,  Kensuke Matsuoka

    IPC分类号： B32B1/02

    CPC分类号： A61F15/001 ,  A61F13/551 ,  A61F2013/00165 ,  A61F2013/00365 ,  Y10T428/13

    摘要： The present invention relates to a patch package structure which includes: a package including a first sheet material and a second sheet material, the first and second sheet materials being sealed together in peripheral parts thereof; and a patch disposed in the package, the patch contains a backing, a pressure-sensitive adhesive layer laminated on at least one side of the backing, and a release liner which protects a pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer, the release liner having on a surface thereof a cut line supporting a peel-off of the release liner at the time of using the patch, the patch being disposed in the package so that the release liner faces the inner surface of the first sheet material, the first sheet material having a first region in which the inner surface of the first sheet material faces the cut line of the release liner, the first sheet material having in the first region a minimum first distance between the inner surface of the first sheet material and the surface of the release liner, and the inner surface of the first sheet material being spaced from the surface of the release liner at the minimum first distance in the first region.

    摘要翻译： 贴片包装结构技术领域本发明涉及一种贴片包装结构，其包括：包括第一片材和第二片材的封装，所述第一片材和第二片材在其周边部分被密封在一起; 以及布置在所述包装中的贴片，所述贴片包含背衬，层压在所述背衬的至少一侧上的压敏粘合剂层以及保护所述压敏粘合剂层的压敏粘合剂表面的剥离衬垫， 所述剥离衬垫在其表面上具有在使用所述贴片时支撑所述剥离衬垫剥离的切割线，所述贴片设置在所述包装中，使得所述剥离衬垫面向所述第一片材的内表面， 所述第一片材具有第一区域，其中所述第一片材的内表面面向所述剥离衬垫的切割线，所述第一片材在所述第一区域中具有所述第一片材的内表面与所述第一片材的内表面之间的最小第一距离， 释放衬垫的表面，并且第一片材的内表面在第一区域中以最小第一距离与释放衬垫的表面间隔开。

    Patch, controller, and method for the photodynamic therapy of a dermal lesion
    6.
    发明授权
    Patch, controller, and method for the photodynamic therapy of a dermal lesion 失效
    用于光动力治疗真皮病变的补片，控制器和方法

    公开(公告)号：US06231593B1

    公开(公告)日：2001-05-15

    申请号：US09000360

    申请日：1998-07-24

    申请人： Peter M. Meserol

    发明人： Peter M. Meserol

    IPC分类号： A61N5067

    CPC分类号： A61M35/00 ,  A61F13/00051 ,  A61F13/0213 ,  A61F2013/00365 ,  A61F2013/00676 ,  A61F2013/00846 ,  A61F2013/00902 ,  A61K9/0009 ,  A61M37/00 ,  A61N5/062 ,  A61N2005/0645

    摘要： An apparatus for photodynamic therapy (PDT) includes a cover (22) shaped to engage skin tissue (12) and a fiber optic panel (31) housed within the cover (22). Hydrogel (26) is located within the cover (22) and is in intimate physical and optical contact with the fiber optic panel (31) for optically coupling light from the fiber optic panel (31) to the skin tissue (12). The hydrogel (26) engages the stratum corneum (14) and hydrates and softens the stratum corneum (14) to enhance its optical transmissiveness to facilitate the transmission of light therethrough and to enhance its chemical transmissiveness to facilitate the transmission therethrough of photopharmaceuticals (28, 54) for treatment of a dermal lesion 10.

    摘要翻译： 一种用于光动力治疗（PDT）的装置包括形成为接合皮肤组织（12）的外壳（22）和容纳在盖（22）内的光纤面板）。 水凝胶（26）位于盖（22）内并与光纤面板（31）保持紧密的物理和光学接触，用于将来自光纤面板（31）的光光学耦合到皮肤组织（12）。 水凝胶（26）接合角质层（14）并水化并软化角质层（14）以增强其透光性，以促进光的透过，并增强其化学传导性，以促进光致药物（28， 54）用于治疗真皮病变10。

    Oxygen producing bandage
    7.
    发明授权
    Oxygen producing bandage 失效
    氧气绷带

    公开(公告)号：US5855570A

    公开(公告)日：1999-01-05

    申请号：US753421

    申请日：1996-11-25

    申请人： Daniel A. Scherson ,  Melvyn I. Burk

    发明人： Daniel A. Scherson ,  Melvyn I. Burk

    IPC分类号： A61F13/00

    CPC分类号： A61F13/00068 ,  A61F13/069 ,  A61F2013/00157 ,  A61F2013/0017 ,  A61F2013/00365 ,  A61F2013/00519 ,  A61F2013/00902 ,  A61F2013/0097

    摘要： A portable, self-contained device is described for the topical application of oxygen to promote the healing of skin wounds. The device is comprised of a wound dressing that incorporates an electrochemical, chemical, or thermal means of generating high purity oxygen. The device can regulate the supply of oxygen to an area above the wound at various concentrations, pressures and dosages. The device is driven by a built in or accessory power source. Ambient air is brought into contact with a gas permeable cathode. Oxygen present in the air is reduced at the cathode to negative ions (i.e. peroxide, superoxide or hydroxyl ions) and/or their unprotonated and protonated neutral species. One or more of these species diffuse through an electrolyte and are then oxidized at a gas permeable anode to produce a high concentration of oxygen directly above the wound. Oxygen can also be depleted from that same area by reversing the polarity of the power source allowing the supply of oxygen to the wound to be modulated, thereby controlling the rate of healing.

    摘要翻译： 描述了便携式，独立的装置，用于局部施用氧气以促进皮肤伤口的愈合。 该装置由包含产生高纯氧的电化学，化学或热装置的伤口敷料组成。 该装置可以以不同的浓度，压力和剂量调节氧气到伤口上方的区域。 该设备由内置或附件电源驱动。 环境空气与透气阴极接触。 存在于空气中的氧在阴极被还原成负离子（即过氧化物，超氧化物或羟基离子）和/或其未质子化和质子化的中性物质。 这些物质中的一种或多种通过电解质扩散，然后在透气阳极处被氧化，以在伤口上方产生高浓度的氧。 通过反转电源的极性，氧也可以从相同的区域消耗，从而允许向伤口供应氧以进行调节，从而控制愈合速率。

    Oxygen producing bandage and method
    8.
    发明授权
    Oxygen producing bandage and method 失效
    氧气绷带和方法

    公开(公告)号：US5578022A

    公开(公告)日：1996-11-26

    申请号：US421679

    申请日：1995-04-12

    申请人： Daniel A. Scherson ,  Melvyn I. Burk

    发明人： Daniel A. Scherson ,  Melvyn I. Burk

    IPC分类号： A61F13/00

    CPC分类号： A61F13/00068 ,  A61F13/069 ,  A61F2013/00157 ,  A61F2013/0017 ,  A61F2013/00365 ,  A61F2013/00519 ,  A61F2013/00902 ,  A61F2013/0097

    摘要： A portable, self-contained device is described for the topical application of oxygen to promote the healing of skin wounds. The device is comprised of a wound dressing that incorporates an electrochemical, chemical, or thermal means of generating high purity oxygen. The device can regulate the supply of oxygen to an area above the wound at various concentrations, pressures and dosages. The device is driven by a built in or accessory power source. Ambient air is brought into contact with a gas permeable cathode. Oxygen present in the air is reduced at the cathode to negative ions (i.e. peroxide, superoxide or hydroxyl ions) and/or their unprotonated and protonated neutral species. One or more of these species diffuse through an electrolyte and are then oxidized at a gas permeable anode to produce a high concentration of oxygen directly above the wound. Oxygen can also be depleted from that same area by reversing the polarity of the power source allowing the supply of oxygen to the wound to be modulated, thereby controlling the rate of healing.

    摘要翻译： 描述了便携式，独立的装置，用于局部施用氧气以促进皮肤伤口的愈合。 该装置由包含产生高纯氧的电化学，化学或热装置的伤口敷料组成。 该装置可以以不同的浓度，压力和剂量调节氧气到伤口上方的区域。 该设备由内置或附件电源驱动。 环境空气与透气阴极接触。 存在于空气中的氧在阴极被还原成负离子（即过氧化物，超氧化物或羟基离子）和/或其未质子化和质子化的中性物质。 这些物质中的一种或多种通过电解质扩散，然后在透气阳极处被氧化，以在伤口上方产生高浓度的氧。 通过反转电源的极性，氧也可以从相同的区域消耗，从而允许向伤口供应氧以进行调节，从而控制愈合速率。

    Method of applying photodynamic therapy to dermal lesion
    9.
    发明授权
    Method of applying photodynamic therapy to dermal lesion 失效
    将光动力疗法应用于真皮病变的方法

    公开(公告)号：US5489279A

    公开(公告)日：1996-02-06

    申请号：US215274

    申请日：1994-03-12

    申请人： Peter M. Meserol

    发明人： Peter M. Meserol

    IPC分类号： A61F13/00 ,  A61F13/02 ,  A61K9/00 ,  A61M35/00 ,  A61M37/00 ,  A61N5/06

    CPC分类号： A61F13/02 ,  A61K9/0009 ,  A61M35/00 ,  A61M37/00 ,  A61N5/062 ,  A61F2013/00365 ,  A61F2013/00676 ,  A61F2013/00846 ,  A61F2013/00902 ,  A61N2005/0645

    摘要： Method of applying photodynamic therapy to dermal lesion located at a dermal treatment site in skin which includes the stratum corneum, including the steps of hydrating the stratum corneum at the dermal treatment site to enhance the chemical and optical transparency of the stratum corneum at the dermal treatment site and to enhance the passage therethrough of photopharmaceutical and light, introducing photopharmaceutical into the treatment site through the hydrated stratum corneum, and introducing light into the treatment site through the hydrated stratum corneum to photoactivate the photopharmaceutical to treat the dermal lesion.

    摘要翻译： 将光动力学治疗应用于位于包括角质层在内的皮肤真皮处理部位的真皮病变的方法，包括在真皮处理部位水合角质层的步骤，以增强真皮处理时角质层的化学和光学透明度 并增强光学药物和光的通过，通过水合角质层将光致药物引入治疗部位，并通过水合角质层将光引入治疗部位以光敏化光致药物以治疗真皮病变。