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公开(公告)号：US11607455B2
公开(公告)日：2023-03-21
申请号：US17030068
申请日：2020-09-23
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A61K41/00 , A61P35/00 , A61K31/336 , A61K31/519
摘要： Methods for treating cancer and/or inducing tumor regression in mammals (e.g., humans) by increasing the metabolism of the mammal, administering a BA dye to the mammal, and thereafter exposing the tumor to actinic light for activation of the BA dye.
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公开(公告)号：US11241429B2
公开(公告)日：2022-02-08
申请号：US16862227
申请日：2020-04-29
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A61K31/4985 , A61K31/00 , A61K45/06 , A61K31/48 , A61P25/24 , A61K31/609
摘要： This invention relates to methods and formulations for treating metabolic disorders and depression. In some embodiments, the methods comprise administering a dopamine receptor agonist and an anti-depressant.
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公开(公告)号：US11000522B2
公开(公告)日：2021-05-11
申请号：US16878451
申请日：2020-05-19
申请人： VeroScience LLC
IPC分类号： A61K31/48 , A61K31/4985 , A61K9/20 , A61K9/14
摘要： The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The formulations are useful for improving glycemic control in the treatment of type 2 diabetes.
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公开(公告)号：US10688094B2
公开(公告)日：2020-06-23
申请号：US16393463
申请日：2019-04-24
申请人： VeroScience LLC
IPC分类号： A61K31/4985 , A61K31/48 , A61K9/20 , A61K9/14
摘要： The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The formulations are useful for improving glycemic control in the treatment of type 2 diabetes.
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公开(公告)号：US10238653B2
公开(公告)日：2019-03-26
申请号：US15809851
申请日：2017-11-10
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A61K31/00 , A61K31/48 , A61K45/06 , A61P25/24 , A61K31/609 , A61K31/4985 , A61K31/59
摘要： This invention relates to methods and formulations for treating metabolic disorders and depression. In some embodiments, the methods comprise administering a dopamine receptor agonist and an anti-depressant.
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6.发明授权公开(公告)号：US09999653B2
公开(公告)日：2018-06-19
申请号：US15158149
申请日：2016-05-18
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A23L1/30 , A61K38/16 , A61K31/198 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/405 , A61K31/70 , A23L33/00 , A23L1/09 , A23L1/29 , A23L1/305 , A61K31/16 , A23L29/212 , A23L29/30 , A23L33/16
CPC分类号： A61K38/16 , A23L5/00 , A23L29/212 , A23L29/30 , A23L33/10 , A23L33/115 , A23L33/16 , A23L33/17 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K31/16 , A61K31/198 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/405 , A61K31/70
摘要： The present invention is directed to a method of treating a patient suffering from the metabolic syndrome and/or related disorders including obesity, Type 2 diabetes, pre-diabetes, hypertension, dyslipidemia, insulin resistance, endothelial dysfunction, pro-inflammatory state, and pro-coagulative state, and comprising the steps of (a) providing to the patient a dietary regimen that decreases overactive CNS noradrenergic tone; followed by (b) providing to the patient a dietary regimen that increases dopaminergic tone while maintaining the above decreased overactive CNS noradrenergic tone. The present invention is also directed to food products useful in implementing the dietary regimens.
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7.发明申请公开(公告)号：US20180140675A1
公开(公告)日：2018-05-24
申请号：US15874430
申请日：2018-01-18
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A61K38/22 , A61K38/26 , A61K31/4985 , A61K38/28 , A61K31/48 , A61K31/4453 , A61K31/198 , A61K31/166
CPC分类号： A61K38/22 , A61K31/166 , A61K31/198 , A61K31/4453 , A61K31/48 , A61K31/4985 , A61K38/26 , A61K38/28 , A61K2300/00
摘要： The present invention is directed to a method of treating a metabolic disorder or key elements of a metabolic disorder such method comprising the use of an agent(s) that increases central dopaminergic activity plus a first-phase insulin secretagouge.
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8.发明授权Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders 有权组合多巴胺激动剂加第一阶段胰岛素促分泌素治疗代谢紊乱公开(公告)号：US09352025B2
公开(公告)日：2016-05-31
申请号：US14506353
申请日：2014-10-03
申请人： VeroScience LLC
发明人： Anthony H. Cincotta
IPC分类号： A61K38/26 , A61K38/28 , A61K31/4985 , A61K31/166 , A61K31/198 , A61K31/4453 , A61K31/48
CPC分类号： A61K38/22 , A61K31/166 , A61K31/198 , A61K31/4453 , A61K31/48 , A61K31/4985 , A61K38/26 , A61K38/28 , A61K2300/00
摘要： The present invention is directed to a method of treating a metabolic disorder or key elements of a metabolic disorder such method comprising the use of an agent(s) that increases central dopaminergic activity plus a first-phase insulin secretagouge.
摘要翻译： 本发明涉及一种治疗代谢紊乱或代谢紊乱的关键因素的方法，所述方法包括使用增加中枢多巴胺能活性加上第一阶段胰岛素分泌物的药剂。
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公开(公告)号：US20140187560A1
公开(公告)日：2014-07-03
申请号：US14088269
申请日：2013-11-22
申请人： VeroScience LLC
IPC分类号： A61K9/14 , A61K31/4985
CPC分类号： A61K31/4985 , A61K9/14 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K9/2072 , A61K9/2077 , A61K9/2095 , A61K31/48
摘要： The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The formulations are useful for improving glycerine control in the treatment of type 2 diabetes.
摘要翻译： 本申请描述了甲磺酸溴隐亭的药物制剂及其制备和使用方法。 该制剂可用于改善治疗2型糖尿病的甘油控制。
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公开(公告)号：US08431155B1
公开(公告)日：2013-04-30
申请号：US13460452
申请日：2012-04-30
CPC分类号： A61K31/4985 , A61K9/14 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K9/2072 , A61K9/2077 , A61K9/2095 , A61K31/48
摘要： The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The formulations are useful for improving glycemic control in the treatment of type 2 diabetes.
摘要翻译： 本申请描述了甲磺酸溴隐亭的药物制剂及其制备和使用方法。 该制剂可用于改善治疗2型糖尿病的血糖控制。
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