ION TRAPS THAT APPLY AN INVERSE MATHIEU Q SCAN

    公开(公告)号:US20190057856A1

    公开(公告)日:2019-02-21

    申请号:US15769998

    申请日:2016-10-21

    Abstract: The invention generally relates to ion traps and methods of use thereof. In certain embodiments, the invention provides a system that includes a mass spectrometer including an ion trap, and a central processing unit (CPU). The CPU has storage that is coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a constant radio frequency (RF) signal to the ion trap, and apply a first alternating current (AC) signal to the ion trap the frequency of which varies as a function of time.

    Locking devices, systems, and methods of use

    公开(公告)号:US12217559B2

    公开(公告)日:2025-02-04

    申请号:US17930777

    申请日:2022-09-09

    Abstract: Locking devices, systems, and methods for securing personal property to separate structures. Such a locking device includes a lock body, a cable within the lock body and having a first end accessible from an exterior of the lock body, a spool for extending and retracting the cable out of and into the lock body, a lock pin disposed at the first end of the cable, a cable lock incorporated into the lock body and configured to releasably secure the lock pin to the lock body, and an electronic communication and control unit incorporated into the lock body and configured to communicate with a remote device. The electronic communication and control unit controls the cable lock to secure and release the lock pin relative to the lock body to allow the remote device to wirelessly unlock the first end of the cable from the lock body.

    APPARATUSES AND METHODS FOR ENABLING ACTIONABLE ANALYSIS OF SUPPORT REQUESTS

    公开(公告)号:US20250036538A1

    公开(公告)日:2025-01-30

    申请号:US18782020

    申请日:2024-07-23

    Abstract: Systems and methods for enabling actionable analysis of support requests are disclosed. Embodiments include systems and methods that ingest support ticket data into an automated workflow (for example, a cron orchestrator), which interacts with one or more databases, one or more APIs, and one or more UIs to supply a user with actionable analysis for, e.g., assisting customers with complex issues. Embodiments may also include one or more ingestion deployments, pre-processing models, pattern-based filtering models, embedding models, message relevancy filtering models, clustering models, anomaly detection models, forecasting models and/or database ingestion models.

    Pinpointing single molecule positions with in situ point spread function retrieval for three dimensional nanoscopy of whole cells and tissues

    公开(公告)号:US12210167B2

    公开(公告)日:2025-01-28

    申请号:US18636195

    申请日:2024-04-15

    Abstract: A method of in situ point spread function (PSF) retrieval is disclosed which includes encoding 3D location of molecules into PSFs, receiving molecule-generated images containing PSFs, segmenting the images into sub-PSF, initializing template PSFs from a pupil function, determining a statistical measure of a predetermined function between the sub- and template PSFs, associating each of the sub-PSFs with a template PSF, aligning and averaging the sub-PSF, applying a phase retrieval algorithm to the averaged sub-PSFs to update the pupil function, regenerating the template PSFs, repeating until a difference between a new and a prior generation pupil function is below a predetermined threshold, generating in situ PSFs from the last pupil function, and applying a maximum likelihood estimation algorithm based on the in situ PSFs and the sub-PSF to thereby generate lateral and axial locations of molecules.

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