-
公开(公告)号：US20090105150A1
公开(公告)日：2009-04-23
申请号：US12150101
申请日：2008-04-24
IPC分类号： A61K38/10 , A61K38/08 , C07K7/14 , C07H21/00 , C12N15/63 , C12N5/00 , A61K31/7052 , A61P37/00
CPC分类号： C07K7/14 , A61K38/00 , A61K39/00 , A61K47/62 , C07K2319/00
摘要： An angiotensin derivative comprising at least one angiotensin peptide moiety coupled to a peptide carrier-binding moiety which can be used for therapy and prophylaxis of conditions associated with the renin activated angiotensin system.
摘要翻译： 包含与肽载体结合部分偶联的至少一种血管紧张素肽部分的血管紧张素衍生物，其可用于治疗和预防与肾素活化的血管紧张素系统相关的病症。
-
公开(公告)号：US20070243182A1
公开(公告)日：2007-10-18
申请号：US10590789
申请日：2005-02-28
申请人： Roger Melton , Anthony Atkinson
发明人： Roger Melton , Anthony Atkinson
CPC分类号： A61K38/4813 , A61K31/519
摘要： A method of combating toxicity caused by an antifolate compound of Formula I, in an individual who has been administered the compound. The method comprises administering an enzyme that has carboxypeptidase G activity to the individual.
摘要翻译： 在给予该化合物的个体中，对抗由式I的抗叶酸化合物引起的毒性的方法。 该方法包括向个体施用具有羧肽酶G活性的酶。
-
公开(公告)号：US07777011B2
公开(公告)日：2010-08-17
申请号：US10116061
申请日：2002-04-05
摘要： Synthetic polypeptides having at least one antigenic site of a prior protein, methods for their use and manufacture, antibodies raised against such polypeptides and diagnostic kits containing these polypeptides or antibodies.
摘要翻译： 具有至少一个先前蛋白质的抗原位点的合成多肽，其使用和制备方法，针对这种多肽产生的抗体以及含有这些多肽或抗体的诊断试剂盒。
-
公开(公告)号：US08637659B2
公开(公告)日：2014-01-28
申请号：US13482110
申请日：2012-05-29
IPC分类号： C08B3/00
CPC分类号： C07H13/06 , A61K9/0019 , A61K39/39 , A61K47/26
摘要： The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to a method of preparation thereof. A mono- and disaccharide derivatives according to the invention comprises at least one fatty acid ester and may further comprise one or more anionic groups and are useful for, inter alia, medical, pharmaceutical, cosmetic and food applications.
摘要翻译： 本发明涉及一种新型的单糖衍生物和二糖衍生物家族及其制备方法。 根据本发明的单糖和二糖衍生物包含至少一种脂肪酸酯，并且还可以包含一个或多个阴离子基团，并且尤其可用于医药，制药，化妆品和食品应用。
-
公开(公告)号：US07378489B1
公开(公告)日：2008-05-27
申请号：US09470997
申请日：1999-12-23
IPC分类号： C07K7/14
CPC分类号： C07K7/14
摘要： An angiotensin derivative comprising at least one angiotensin peptide moiety coupled to a peptide carrier-binding moiety which can be used for therapy and prophylaxis of conditions associated with the renin activated angiotensin system.
摘要翻译： 包含与肽载体结合部分偶联的至少一种血管紧张素肽部分的血管紧张素衍生物，其可用于治疗和预防与肾素活化的血管紧张素系统相关的病症。
-
公开(公告)号：US08052981B2
公开(公告)日：2011-11-08
申请号：US12386577
申请日：2009-04-20
IPC分类号： A61K45/00
CPC分类号： C07H13/06 , A61K9/0019 , A61K39/39 , A61K47/26
摘要： The present invention includes a formulation comprising a physiological salt solution, or an oil-in-water emulsion, or a water immiscible solid phase, and an adjuvant comprising one or more disaccharide derivatives derived from cellobiose, gentiobiose, lactose, lactulose, maltose, melibiose, sucrose or turanose, wherein at least four of the free hydroxyl groups of the disaccharide molecule have been modified such that the disaccharide derivative has: (i) at least 3, but not more than N-1, fatty acid ester groups, wherein each of the fatty acid ester groups is represented by a general formula of —O—C(═O)—(CH2)xCH3 wherein x is between 6 and 14, and (ii) at least one, but no more than N-1 anionic groups, wherein N is the number of hydroxyl groups of the disaccharide from which the derivative is derived and wherein the combined number of fatty acid esters and anionic groups does not exceed N.
摘要翻译： 本发明包括一种包含生理盐溶液或水包油乳剂或与水不混溶的固相的制剂，和包含一种或多种衍生自纤维二糖，龙胆糖，乳糖，乳果糖，麦芽糖，蜜二糖的二糖衍生物的佐剂 ，蔗糖或吐拉糖，其中二糖分子的至少四个游离羟基被修饰，使得二糖衍生物具有：（i）至少3个但不大于N-1个脂肪酸酯基团，其中每个 的脂肪酸酯基团由通式-O-C（= O） - （CH 2）x CH 3表示，其中x在6和14之间，和（ii）至少一个，但不超过N-1个阴离子 基团，其中N是衍生物衍生自其的二糖的羟基数，并且其中脂肪酸酯和阴离子基团的组合数不超过N.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.018 秒)
