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    Compositions comprising hydroxytyrosol and boswellic acid
    2.
    发明授权
    Compositions comprising hydroxytyrosol and boswellic acid 有权

    公开(公告)号：US11241444B2

    公开(公告)日：2022-02-08

    申请号：US16830454

    申请日：2020-03-26

    申请人： Nutramax Laboratories, Inc.

    发明人： Todd Henderson ,  David Griffin

    IPC分类号： A61K31/56 ,  A61K31/05 ,  A61K36/63 ,  A61K36/324

    摘要： Compositions are described including a combination of hydroxytyrosol and 3-O-acetyl-11-keto-β-boswellic acid. The hydroxytyrosol may be sourced from an olive extract and the 3-O-acetyl-11-keto-β-boswellic acid may be sourced from a Boswellia serrata extract. The compositions may be formulated for oral administration to a mammalian or an avian subject. Methods for preventing or reducing an inflammatory response in connective tissue are provided, the methods comprising orally administering the compositions to a subject in need thereof.

    Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
    9.
    发明申请
    Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals 审中-公开
    使用合成代谢剂，抗分解代谢剂，抗氧化剂和止痛剂来保护，治疗和修复人类和动物中的结缔组织

    公开(公告)号：US20070141181A1

    公开(公告)日：2007-06-21

    申请号：US11634383

    申请日：2006-12-06

    申请人： Todd Henderson ,  Carmelita Frondoza

    发明人： Todd Henderson ,  Carmelita Frondoza

    IPC分类号： A61K36/736 ,  A61K31/56 ,  A61K31/7008 ,  A61K31/737 ,  A61K36/48

    CPC分类号： A61K31/7008 ,  A61K31/56 ,  A61K31/737 ,  A61K36/48 ,  A61K36/54 ,  A61K2300/00

    摘要： The present invention relates to compositions for the modulation of inflammation in connective tissues in humans and animals and the modulation of markers of such inflammation, including COX-2, TNF-α, IL-1β, iNOS, p38, and chemokines, comprising any or all of anabolic, anti-catabolic, anti-oxidant and analgesic agents, including aminosugars, S-adenosylmethionine, arachadonic acid, GAGs, including pentosan, collagen type II, tetracyclines or tetracycline-like compounds, diacerin, super oxide dismutase, L-ergothioneine, methylsulfanylmethane, one or more avocado/soybean unsaponifiables, and an analgesic, e.g., acetaminophen, and to methods of treating humans and animals by administration of these novel compositions to humans and animals in need thereof.

    摘要翻译： 本发明涉及用于调节人和动物结缔组织中炎症的组合物以及这种炎症的标志物的调节，包括COX-2，TNF-α，IL-1β，iNOS，p38和趋化因子，包括任何或 所有合成代谢，抗分解代谢，抗氧化和止痛剂，包括氨基糖，S-腺苷甲硫氨酸，花生四烯酸，GAGs，包括戊聚糖，II型胶原，四环素或四环素样化合物，diacerin，超氧化物歧化酶，L-麦角硫杆菌素 甲基硫烷基甲烷，一种或多种鳄梨/大豆不皂化物，以及止痛剂，例如对乙酰氨基酚，以及通过将这些新型组合物施用于有需要的人和动物来治疗人和动物的方法。

    L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage
    10.
    发明申请
    L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage 审中-公开
    L-麦角硫素，乳蓟和s-腺苷甲硫氨酸用于预防，治疗和修复肝损伤

    公开(公告)号：US20010000472A1

    公开(公告)日：2001-04-26

    申请号：US09731719

    申请日：2000-12-08

    申请人： Nutramax Laboratories, Inc.

    发明人： Todd R. Henderson ,  Barbara E. Corson

    IPC分类号： A61K035/78 ,  A61K031/7076 ,  A61K031/4164

    CPC分类号： A61K36/28 ,  A61K31/357 ,  A61K31/4172 ,  A61K31/7076 ,  A61K2300/00

    摘要： This invention provides therapeutic compositions and combinations for the protection, treatment and repair of liver tissue. The invention relates to novel compositions and combinations comprising two or more compounds selected from the group consisting of S-adenosylmethionine, L-ergothioneine, and a substance selected from the group consisting of constituents of Milk thistle (Silybum marianum), silymarin and active components of silymarin, whether naturally, synthetically, or semi-synthetically derived, and to methods of preventing and treating liver disease and of repairing damaged liver tissue. The invention also provides a method of administering these compositions and combinations to humans or animals in need thereof.

    摘要翻译： 本发明提供用于肝组织的保护，治疗和修复的治疗组合物和组合。 本发明涉及包含两种或更多种选自S-腺苷甲硫氨酸，L-麦角硫素和选自以下的物质的新型组合物和组合：选自下组的物质：乳蓟（Silybum marianum），水飞蓟素和水飞蓟素的组分 水飞蓟素，无论是天然的，合成的还是半合成的，以及预防和治疗肝脏疾病和修复受损的肝组织的方法。 本发明还提供了将这些组合物和组合施用于有需要的人或动物的方法。