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公开(公告)号：US10696739B2
公开(公告)日：2020-06-30
申请号：US16250733
申请日：2019-01-17
申请人： rPeptide LLC
摘要： The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.
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公开(公告)号：US11161898B2
公开(公告)日：2021-11-02
申请号：US16678649
申请日：2019-11-08
申请人： rPeptide LLC
IPC分类号： C07K16/18 , G01N33/68 , A61K39/395 , A61P25/28 , A61K39/00
摘要： The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the amyloid-beta (Aβ) protein. Such antibodies may be used for the modulation of Aβ activity and/or aggregation or amyloidosis, to study the effects of the Aβ protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with Aβ activity, aggregation, and/or amyloidosis.
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公开(公告)号：US20190211086A1
公开(公告)日：2019-07-11
申请号：US16250733
申请日：2019-01-17
申请人： rPeptide LLC
CPC分类号： C07K16/18 , A61K49/0002 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , G01N33/6896 , G01N2333/47 , G01N2800/28
摘要： The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.
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公开(公告)号：US10202444B2
公开(公告)日：2019-02-12
申请号：US15552633
申请日：2016-02-23
申请人： rPeptide LLC
摘要： The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau protein. Such antibodies may be used for the modulation of tau activity and/or aggregation, to study the effects of the tau protein on cell function and, in certain embodiments, for the treatment and/or prevention of a disease or condition associated with neurodegenerative tauopathy.
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