公开(公告)号：US11786575B2

公开(公告)日：2023-10-17

申请号：US17696955

申请日：2022-03-17

Applicant: Zoetis Services LLC

Inventor： Michael P. Curtis ,  Susan M. Sheehan ,  Graham M. Kyne ,  Matthew W. Bedore ,  Richard A. Ewin ,  Paul D. Johnson ,  Tom L. McTier ,  Christopher S Knauer ,  Rajendran Vairagoundar

IPC: A61K38/15 ,  A61P33/00 ,  C07K11/02 ,  A61K31/35 ,  A61K31/4188 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/7048 ,  A61K38/00

CPC classification number: A61K38/15 ,  A61K31/35 ,  A61K31/4188 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/7048 ,  A61P33/00 ,  C07K11/02 ,  A61K38/00

Abstract: The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof




wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.