公开(公告)号：US07911378B2

公开(公告)日：2011-03-22

申请号：US12340119

申请日：2008-12-19

申请人： Yufeng Zhang ,  Yang Gao ,  Suen Lee

发明人： Yufeng Zhang ,  Yang Gao ,  Suen Lee

IPC分类号： G01S19/43 ,  G01S19/30

CPC分类号： G01S19/41 ,  G01S19/43

摘要： A method and system for approximating a position using a Global Navigational Satellite System (GNSS) having a plurality of GNSS satellites and an augmentation system, the method including the steps of obtaining an initial code pseudorange measurement and an initial carrier phase measurement from a signal transmitted by a GNSS satellite in the GNSS system, receiving a code correction from the augmentation system, using the code correction to correct the initial code pseudorange measurement and the initial carrier phase measurement to mitigate for errors in the signal, to result in a corrected code pseudorange measurement and a corrected carrier phase measurement, and using a code dominated measurement in a filter which outputs apposition and ambiguity estimate.

摘要翻译： 一种使用具有多个GNSS卫星和增强系统的全球导航卫星系统（GNSS）近似位置的方法和系统，所述方法包括以下步骤：从传输的信号获得初始码伪距测量和初始载波相位测量 通过GNSS系统中的GNSS卫星，从增强系统接收码校正，使用码校正来校正初始码伪距测量和初始载波相位测量以减轻信号中的错误，导致校正码伪距 测量和校正的载波相位测量，并且在输出相位和模糊度估计的滤波器中使用代码主导测量。

公开(公告)号：US08456354B2

公开(公告)日：2013-06-04

申请号：US12954651

申请日：2010-11-25

申请人： Yufeng Zhang ,  Yang Gao ,  Suen Lee

发明人： Yufeng Zhang ,  Yang Gao ,  Suen Lee

IPC分类号： G01S19/43 ,  G01S19/30

CPC分类号： G01S19/43 ,  G01S19/07 ,  G01S19/30 ,  G01S19/423

摘要： A method for determining a position using a GNSS system having a plurality of GNSS satellites and one or more augmentation systems, which method includes the steps of obtaining a code or phase measurement from the GNSS satellite signals, generating measurement groups, and generating corrected measurement groups by applying code or phase corrections from the augmentation systems, and applying combinations of the corrected measurements in a filter which outputs a position and ambiguity estimate.

摘要翻译： 一种使用具有多个GNSS卫星和一个或多个增强系统的GNSS系统来确定位置的方法，所述方法包括以下步骤：从GNSS卫星信号获得码或相位测量，产生测量组，以及产生经校正的测量组 通过从增强系统应用代码或相位校正，以及在输出位置和模糊度估计的滤波器中应用校正测量的组合。

公开(公告)号：US20090037106A1

公开(公告)日：2009-02-05

申请号：US11974391

申请日：2007-10-11

申请人： Alexei Gavriline ,  Mamdouh Yanni ,  Yang Gao ,  Yufeng Zhang

发明人： Alexei Gavriline ,  Mamdouh Yanni ,  Yang Gao ,  Yufeng Zhang

IPC分类号： G01C21/00

CPC分类号： G01C25/00

摘要： A real-time integrated Global Positioning System (GPS) and Inertial Navigation System (INS) system in which each aids the other to offer continuously available navigation information by each GPS and INS subsystem calculating an initial solution, providing the initial solution to the other GPS or INS subsystem, and then each GPS and INS subsystem calculating a collaborative solution based on the initial solution received from the other GPS or INS subsystem.

摘要翻译： 实时综合全球定位系统（GPS）和惯性导航系统（INS）系统，其中每个辅助对象提供连续可用的导航信息，由每个GPS和INS子系统计算初始解决方案，为其他GPS提供初始解决方案 或INS子系统，然后每个GPS和INS子系统基于从其他GPS或INS子系统接收的初始解决方案计算协作解决方案。

公开(公告)号：US10253289B2

公开(公告)日：2019-04-09

申请号：US15304205

申请日：2015-04-17

申请人： Zulfiya Orynbayeva ,  Gennady Friedman ,  Yury Gogotsi ,  Yang Gao

发明人： Zulfiya Orynbayeva ,  Gennady Friedman ,  Yury Gogotsi ,  Yang Gao

IPC分类号： C12M1/00 ,  G01N33/50 ,  G01N33/52 ,  G01N33/497 ,  C12M1/12 ,  C12M1/34 ,  B01L3/02

摘要： A method and apparatus for carrying out measurements on single cells, either one or many single cells at a time in order to characterize the cellular response to stimuli in a perfused liquid. The apparatus for performing the respirometry includes a double-barrel pipette probe.

公开(公告)号：US09885080B2

公开(公告)日：2018-02-06

申请号：US13811634

申请日：2011-05-31

申请人： Yang Gao ,  Daixing Zhou ,  Jianguang Zhang ,  Feng Tian

发明人： Yang Gao ,  Daixing Zhou ,  Jianguang Zhang ,  Feng Tian

IPC分类号： C12Q1/68 ,  G06F19/20

CPC分类号： C12Q1/6874 ,  C12Q1/6809 ,  C12Q1/6869 ,  G06F19/20 ,  C12Q2535/122 ,  C12Q2537/16 ,  C12Q2537/165 ,  C12Q2563/159

摘要： The invention relates to a kit, a device and a method for detecting the copy number of fetal chromosomes and tumor cell chromosomes. The method for detecting the copy number of fetal chromosomes or tumor cell chromosomes of the invention includes the following steps: collecting maternal plasma or plasma of tumor patient; separating the plasma from blood cells in blood; preparing Deoxyribonucleic Acids (DNA) in the plasma into a sequencing library; sequencing the DNA sequencing library; comparing a sequencing result with a genomic sequence map to determine which chromosome the DNA sequence comes from and the length of each DNA sequence; and calculating the ratio of the DNA segments from the chromosomes to be detected to all DNA segments in the same sample by a sequencing and comparison result of DNA, correcting the ratio according to a GC content of the DNA segments from the chromosomes to be detected, and calculating the variation of the corrected ratio of the DNA segments from the chromosomes to be detected in a sample to be detected, and determining the copy number of the chromosomes to be detected according to degree of variation.

公开(公告)号：US09589572B2

公开(公告)日：2017-03-07

申请号：US14702687

申请日：2015-05-02

申请人： Yang Gao

发明人： Yang Gao

IPC分类号： A61F11/06 ,  G10L21/0208 ,  G10L21/0216

CPC分类号： G10L21/0208 ,  G10L2021/02166

摘要： In accordance with an embodiment of the present invention, a noise reduction method for speech processing includes estimating a noise/interference component signal by subtracting voice component signal from a first microphone input signal wherein the voice component signal is evaluated as a first replica signal produced by passing a second microphone input signal through a first adaptive filter; a stepsize is estimated to control adaptive update of the first adaptive filter, wherein the stepsize is evaluated by combing an open-loop approach and a closed-loop approach, the open-loop approach comprising voice/noise/interference classification and SNR estimation in voice area, and the closed-loop approach comprising calculating a normalized correlation between the first replica signal and the first microphone input signal. A noise/interference reduced signal is outputted by subtracting a second replica signal from a target signal which is the first microphone input signal or the second microphone input signal, wherein the second replica signal is produced by passing the estimated noise/interference component signal through a second adaptive filter.

摘要翻译： 根据本发明的实施例，用于语音处理的噪声降低方法包括：通过从第一麦克风输入信号中减去语音分量信号来估计噪声/干扰分量信号，其中语音分量信号被评估为第一复制信号，其由 通过第一自适应滤波器传递第二麦克风输入信号; 估计步长来控制第一自适应滤波器的自适应更新，其中通过组合开环方法和闭环方法评估步长，包括语音/噪声/干扰分类和声音中的SNR估计的开环方法 区域和闭环方法，包括计算第一复制信号和第一麦克风输入信号之间的归一化相关性。 通过从作为第一麦克风输入信号或第二麦克风输入信号的目标信号减去第二复制信号来输出噪声/干扰降低信号，其中通过将估计的噪声/干扰分量信号通过一个 第二自适应滤波器。

公开(公告)号：US09540687B2

公开(公告)日：2017-01-10

申请号：US14347113

申请日：2012-07-11

申请人： Jianguang Zhang ,  Zhongchun Zhou ,  Daixing Zhou ,  Genming Xu ,  Yang Gao ,  Feng Tian

发明人： Jianguang Zhang ,  Zhongchun Zhou ,  Daixing Zhou ,  Genming Xu ,  Yang Gao ,  Feng Tian

IPC分类号： C12Q1/68

CPC分类号： C12Q1/686 ,  C12Q2521/501 ,  C12Q2525/307

摘要： The disclosure claims a cleaved Deoxyribonucleic acid (DNA) detection method, a DNA fragment detection kit and use thereof. Wherein, the method includes the steps of: designing primers according to a test site or a test region of the DNA fragment; cyclizing the DNA fragment to obtain acyclized DNA; implementing Polymerase Chain Reaction (PCR) amplification for the cyclized DNA by using the primers; and detecting the PCR amplification product. In the disclosure, by cyclizing the DNA fragment, the amplification can be implemented even if only one PCR primer can match with a template, thus, the adaption range and effective template amount of the primer amplification can be greatly increased, and the detection sensitivity of the DNA fragment can be greatly improved.

摘要翻译： 本公开要求切割的脱氧核糖核酸（DNA）检测方法，DNA片段检测试剂盒及其用途。 其中该方法包括以下步骤：根据DNA片段的测试位点或测试区设计引物; 使DNA片段环化以获得非环化DNA; 通过使用引物对环化DNA进行聚合酶链反应（PCR）扩增; 并检测PCR扩增产物。 在本公开中，通过使DNA片段环化，即使只有一个PCR引物可以与模板匹配，也可以实现扩增，因此可以大大增加引物扩增的适应范围和有效模板量，并且检测灵敏度 DNA片段可以大大提高。

公开(公告)号：US09510096B2

公开(公告)日：2016-11-29

申请号：US14702688

申请日：2015-05-02

申请人： Yang Gao

发明人： Yang Gao

IPC分类号： G10K11/16 ,  H04R3/00 ,  G10K11/178 ,  H04R5/04

CPC分类号： H04R3/005 ,  G10K11/178 ,  H04R3/002 ,  H04R5/04 ,  H04R2201/403 ,  H04R2410/01

摘要： In accordance with an embodiment of the present invention, a noise reduction method for speech processing includes cancelling or reducing noise/interference component signal in speech signal enhancement processing, the method comprising estimating the noise/interference component signal by subtracting voice component signal from a first microphone input signal wherein the voice component signal is evaluated as a first replica signal produced by passing a second microphone input signal through a first adaptive filter. Energy variation of the noise/interference component signal is adjusted based on noise stability detection and/or energy explosion detection, wherein the energy of the noise/interference component signal is reduced or smoothed in voice area or energy explosion area if the stable noise is detected and/or the energy explosion is detected. A noise/interference reduced signal is outputted by subtracting a second replica signal from the target signal, wherein the second replica signal is produced by passing the adjusted noise/interference component signal through a second adaptive filter.

摘要翻译： 根据本发明的实施例，用于语音处理的噪声降低方法包括：消除或减少语音信号增强处理中的噪声/干扰分量信号，所述方法包括：通过从第一信号中减去语音分量信号来估计噪声/干扰分量信号 麦克风输入信号，其中语音分量信号被评估为通过使第二麦克风输入信号通过第一自适应滤波器而产生的第一复制信号。 基于噪声稳定性检测和/或能量爆炸检测来调整噪声/干扰分量信号的能量变化，其中如果检测到稳定的噪声，噪声/干扰分量信号的能量在话音区域或能量爆炸区域被减少或平滑 和/或检测到能量爆炸。 通过从目标信号中减去第二副本信号来输出噪声/干扰减小信号，其中通过使调整的噪声/干扰分量信号通过第二自适应滤波器来产生第二复制信号。

公开(公告)号：US09443531B2

公开(公告)日：2016-09-13

申请号：US14702686

申请日：2015-05-02

申请人： Yang Gao

发明人： Yang Gao

IPC分类号： G10L21/00 ,  G10L21/0208 ,  G10L21/0216

CPC分类号： G10L21/0208 ,  G10L2021/02163 ,  G10L2021/02166

摘要： In accordance with an embodiment of the present invention, a noise reduction method for speech processing includes detecting if two signals from two microphones are so close to each other in non voice area that the two microphones are equivalent to Single-Microphone for noise/interference reduction processing. Single-Microphone noise/interference reduction processing algorithm is selected if the equivalent Single-Microphone is detected; Multiple-Microphone noise/interference reduction processing algorithm is selected if the equivalent Single-Microphone is not detected.

摘要翻译： 根据本发明的实施例，用于语音处理的噪声降低方法包括检测来自两个麦克风的两个信号是否在非语音区域中彼此如此接近，使得两个麦克风相当于用于噪声/干扰减少的单麦克风 处理。 如果检测到等效的单麦克风，则选择单麦克风噪声/干扰减少处理算法; 如果未检测到等效的单麦克风，则选择多麦克风噪声/干扰减少处理算法。

公开(公告)号：US09401156B2

公开(公告)日：2016-07-26

申请号：US12215649

申请日：2008-06-27

申请人： Huan-Yu Su ,  Yang Gao

发明人： Huan-Yu Su ,  Yang Gao

IPC分类号： G10L19/09 ,  G10L19/12 ,  G10L19/18 ,  G10L19/20 ,  G10L25/90 ,  G10L19/02 ,  G10L19/00

CPC分类号： G10L19/12 ,  G10L19/0204 ,  G10L19/09 ,  G10L19/18 ,  G10L19/20 ,  G10L25/90 ,  G10L2019/0002 ,  G10L2019/0016

摘要： There is provided a method of using an adaptive tilt compensation by a speech decoder. The method comprises receiving a bit stream including a plurality of parameters representative of a speech signal; identifying an adaptive code vector and a fixed code vector using the plurality of parameters; scaling the adaptive code vector and the fixed code vector to generate a scaled adaptive code vector and a scaled fixed code vector; summing the scaled adaptive code vector and the scaled fixed code vector to generate a synthesized output; calculating a first reflection coefficient based on the plurality of parameters representative of the speech signal; multiplying the first reflection coefficient by a factor to generate a tilt factor; and applying the tilt factor to the synthesized output based on an encoding bit rate.

摘要翻译： 提供了一种通过语音解码器使用自适应倾斜补偿的方法。 该方法包括：接收包括表示语音信号的多个参数的比特流; 使用所述多个参数来识别自适应码矢量和固定码矢量; 缩放自适应码矢量和固定码矢量以生成缩放的自适应码矢量和缩放的固定码矢量; 对经缩放的自适应码矢量和缩放的固定码矢量求和以产生合成输出; 基于表示所述语音信号的多个参数来计算第一反射系数; 将第一反射系数乘以因子以产生倾斜因子; 以及基于编码比特率将所述倾斜因子应用于所述合成输出。