公开(公告)号：US4908472A

公开(公告)日：1990-03-13

申请号：US291207

申请日：1988-12-28

申请人： Usaji Takaki ,  Shinobu Aoki ,  Yoshihiro Yamamoto ,  Isao Hara

发明人： Usaji Takaki ,  Shinobu Aoki ,  Yoshihiro Yamamoto ,  Isao Hara

IPC分类号： B01J23/44 ,  B01J10/00 ,  B01J19/00 ,  B01J27/122 ,  B01J27/13 ,  B01J31/04 ,  B01J31/22 ,  C07B61/00 ,  C07C67/36 ,  C07C69/618

CPC分类号： B01J19/0013 ,  B01J19/0066 ,  C07C67/36 ,  B01J2219/00094 ,  B01J2219/00108

摘要： The invention relates to a process for preparing a cinnamate ester comprising forming a reaction mixture of a styrene compound, an alcohol and a catalyst in a reactor; blowing a feed gas mixture of carbon monoxide, oxygen and an inert gas into the reaction mixture through at least one feed port; collecting a discharge gas flowing from the reactor and passing the gas through a condenser to form a condensate; recirculating the condensate into the reactor; blowing into the reaction mixture through at least one feed port other than the feed port(s) for the feed gas mixture, a gas selected from the groups consisting of the discharge gas and an inert gas; and isolating the cinnamate ester from the mixture.

公开(公告)号：US5187283A

公开(公告)日：1993-02-16

申请号：US796265

申请日：1991-11-21

申请人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Yoshihisa Inoue ,  Isao Hara

发明人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Yoshihisa Inoue ,  Isao Hara

IPC分类号： C09B7/02

CPC分类号： C09B7/02

摘要： An indigo compound is prepared from a corresponding indole compound which is unsubstituted at the 2- and 3- positions. The indole compound and an organic hydroperoxide are reacted in the presence of a catalyst which is a metal selected from the group consisting of the metals of Groups 4, 5 and 6 of the periodic table or a compound of the metal. The reaction is conducted while taking out water from a reaction system, said water being that introduced in the reaction system or formed during the reaction, or while controlling the amount of water, which is introduced in the reaction system, at a level not greater than 1 mole per mole of the indole compound.

公开(公告)号：US4966977A

公开(公告)日：1990-10-30

申请号：US324503

申请日：1989-03-16

申请人： Usaji Takaki ,  Shinobu Aoki ,  Yoshihiro Yamamoto ,  Isao Hara

发明人： Usaji Takaki ,  Shinobu Aoki ,  Yoshihiro Yamamoto ,  Isao Hara

IPC分类号： C09B7/00

CPC分类号： C09B7/00

摘要： A process for the preparation of an indigo compound by reacting an indole compound having no substituent at the 2- and 3-positions with hydrogen peroxide in a liquid phase composed of at least two separate phases including an organic phase containing the indole compound and an aqueous phase containing hydrogen peroxide, or by reacting the indole compound with hydrogen peroxide in solution in an organic solvent.

公开(公告)号：US5112987A

公开(公告)日：1992-05-12

申请号：US426375

申请日：1989-10-25

申请人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Isao Hara

发明人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Isao Hara

IPC分类号： C07D209/36 ,  C09B7/02

CPC分类号： C07D209/36 ,  C09B7/02

摘要： A process for the preparation of an indigo compound which comprises reacting a corresponding indole compound having no substituent at the 2- and 3-positions with a percarboxylic acid in the presence of an alcohol solvent, or with heating over 60.degree. C. in the presence of an aprotic solvent.

摘要翻译： 一种制备靛蓝化合物的方法，该方法包括在醇溶剂存在下使相应的2-位和3位上不具有取代基的吲哚化合物与过羧酸反应，或在60℃加热 的非质子溶剂。

公开(公告)号：US4992556A

公开(公告)日：1991-02-12

申请号：US314021

申请日：1989-02-23

申请人： Usaji Takaki ,  Hiroharu Suzuki ,  Yoshihiro Yamamoto ,  Shinobu Aoki ,  Isao Hara

发明人： Usaji Takaki ,  Hiroharu Suzuki ,  Yoshihiro Yamamoto ,  Shinobu Aoki ,  Isao Hara

IPC分类号： C09B7/00

CPC分类号： C09B7/00

摘要： An indigo compound is prepared by reacting an indole compound unsubstituted at the 2- and 3-positions with an organic hydroperoxide, preferably in the presence of a metallic compound catalyst capable of catalyzing the oxidation of the carton atom at the 3-position of the indole compound, such as a compound of a metal of group 4A, 5A or 6A of the periodic table.

公开(公告)号：US4973706A

公开(公告)日：1990-11-27

申请号：US343459

申请日：1989-04-25

申请人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Isao Hara

发明人： Yoshihiro Yamamoto ,  Usaji Takaki ,  Shinobu Aoki ,  Isao Hara

IPC分类号： C07D209/36 ,  C09B7/02

CPC分类号： C07D209/36 ,  C09B7/02

摘要： Disclosed is a process for preparing an indigo compound in improved yield by reacting indole or other indole compound having no substituent at the 2- and 3-positions with an organic hydroperoxide in the presence of an additive selected from the group consisting of (1) a carboxyl compound and (2) a boric acid ester compound. The yield of the indigo compound can further be increased by using a metallic compound catalyst capable of oxidizing carbon atom at the 3-position of the indole compound, such as a compound of a metal of group 4A, 5A or 6A of the periodic table.

公开(公告)号：US20080033154A1

公开(公告)日：2008-02-07

申请号：US11629517

申请日：2005-06-02

申请人： Yoshihisa Inoue ,  Setsuko Funaki ,  Tetsuya Hamada ,  Yoshihiro Yamamoto ,  Isao Hara ,  Takaomi Hayashi ,  Miyuki Konno ,  Shinobu Aoki

发明人： Yoshihisa Inoue ,  Setsuko Funaki ,  Tetsuya Hamada ,  Yoshihiro Yamamoto ,  Isao Hara ,  Takaomi Hayashi ,  Miyuki Konno ,  Shinobu Aoki

IPC分类号： C07D307/02 ,  C07H5/06

CPC分类号： C07D307/14

摘要： A 3-aminomethyltetrahydrofuran derivative is produced by preparing a 3-cyanotetrahydrofuran derivative in a high yield from a malic acid derivative, and reducing the cyano group of the 3-cyanotetrahydrofuran derivative. The process can produce the 3-cyanotetrahydrofuran derivative in a high yield from inexpensive industrial materials.

摘要翻译： 通过从苹果酸衍生物制备高收率的3-氰基四氢呋喃衍生物，并还原3-氰基四氢呋喃衍生物的氰基，制备3-氨基甲基四氢呋喃衍生物。 该方法可以从廉价的工业材料以高产率生产3-氰基四氢呋喃衍生物。

公开(公告)号：US06177593B1

公开(公告)日：2001-01-23

申请号：US09216864

申请日：1998-12-21

申请人： Tadahito Nobori ,  Takaomi Hayashi ,  Katsuhiko Funaki ,  Atsushi Shibahara ,  Isao Hara ,  Shinji Kiyono ,  Kazumi Mizutani ,  Usaji Takaki

发明人： Tadahito Nobori ,  Takaomi Hayashi ,  Katsuhiko Funaki ,  Atsushi Shibahara ,  Isao Hara ,  Shinji Kiyono ,  Kazumi Mizutani ,  Usaji Takaki

IPC分类号： C07F902

CPC分类号： C07F9/065

摘要： The compound [tris(dimethylamino)phosphonioamino]tris[tris(dimethylamino)phosphoranylideneamino]phosphonium dichloride can be prepared by contacting hydrogen chloride with tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride. The phosphonium dichloride compound can be used in a process wherein it is brought into contact with an OH−-form ion exchange resin to prepare tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium hydroxide. Separate processes for separating or isolating the phosphonium chloride compound or isolating the phosphonium hydroxide compound from feed solutions wherein an extraction step is used are also set forth.

摘要翻译： 化合物[三（二甲基氨基）膦酰氨基]三[三（二甲基氨基）亚正膦基氨基]二氯化鏻可以通过使氯化氢与四[三（二甲基氨基）正膦亚基氨基]鏻氯化物接触来制备。 二氯化鏻化合物可以在与OH型离子交换树脂接触以制备四[三（二甲基氨基）正膦亚基氨基]鏻氢氧化物的方法中使用。 还提出了分离或分离氯化鏻化合物或从使用提取步骤的进料溶液中分离氢氧化鏻的分离方法。

公开(公告)号：US06255537B1

公开(公告)日：2001-07-03

申请号：US09289990

申请日：1999-04-13

申请人： Takaomi Hayashi ,  Katsuhiko Funaki ,  Atsushi Shibahara ,  Kazumi Mizutani ,  Isao Hara ,  Shinji Kiyono ,  Tadahito Nobori ,  Usaji Takaki

发明人： Takaomi Hayashi ,  Katsuhiko Funaki ,  Atsushi Shibahara ,  Kazumi Mizutani ,  Isao Hara ,  Shinji Kiyono ,  Tadahito Nobori ,  Usaji Takaki

IPC分类号： C07C4313

CPC分类号： C08G65/2675 ,  C08G65/10 ,  C08G65/2663

摘要： There is provided a process for preparing a poly(alkylene oxide) by using a polymerization initiator which does not cause any problem on preparing and handling in the preparation of the polyalkylene oxide by polymerizing an alkylene oxide compound and does not require a special treatment before the initiation of the polymerization. That is, it is a process of polymerizing the alkylene oxide compound in the presence of a phosphine oxide compound represented by the formula (1): wherein R is the same or different and each represents a hydrocarbon group having 1 to 10 carbon atoms, and x represents an amount of water molecules contained in terms of a molar ratio and is within a range from 0 to 5.0, or in the presence of said phosphine oxide compound and an active hydrogen compound selected from water or an organic compound having a partial structural formula —OH or —NH—.

摘要翻译： 提供了一种通过使用聚合引发剂制备聚（环氧烷）的方法，该聚合引发剂在通过聚合烯化氧化合物制备聚环氧烷的制备和处理中不会引起任何问题，并且不需要在 引发聚合。 也就是说，它是在式（1）表示的氧化膦化合物存在下使烯化氧化合物聚合的方法：其中R相同或不同，各自代表具有1-10个碳原子的烃基，和 x表示以摩尔比表示的水分子的含量，在0〜5.0的范围内，或在所述氧化膦化合物和活性氢化合物存在下，选自水或具有部分结构式的有机化合物 -OH或-NH-。

公开(公告)号：US6153794A

公开(公告)日：2000-11-28

申请号：US348586

申请日：1999-07-07

申请人： Katsuhiko Funaki ,  Isao Hara ,  Takaomi Hayashi ,  Shinji Kiyono ,  Atsushi Shibahara ,  Kazumi Mizutani ,  Tadahito Nobori ,  Usaji Takaki

发明人： Katsuhiko Funaki ,  Isao Hara ,  Takaomi Hayashi ,  Shinji Kiyono ,  Atsushi Shibahara ,  Kazumi Mizutani ,  Tadahito Nobori ,  Usaji Takaki

IPC分类号： C07F9/53 ,  C07F9/06 ,  C07F9/22 ,  C08G65/26 ,  C07C43/11 ,  C07C69/76

CPC分类号： C07F9/224 ,  C07F9/065 ,  C08G65/2675

摘要： An organic compound which is basic and soluble in an organic solvent, does not have a problem in preparation or handling and exhibits catalytic activity as a basic compound, i.e., a phosphine sulfide represented by formula (1), and a manufacturing process therefor, i.e., manufacturing a phosphine sulfide represented by formula (1), by reacting one molecule of thiophosphoryl chloride with three molecules of a phosphorane represented by formula (2). The phosphine sulfide can be used in a process for effectively manufacturing a poly(alkylene oxide) by polymerizing an alkylene oxide in the presence of the phosphine sulfide or of the phosphine sulfide and an active hydrogen compound selected from water and organic compounds having a partial structure of --OH or --NH--; and 2) a process for manufacturing a 1,2-dioxyethane derivative from an epoxy compound, i.e, manufacturing a 1,2-dioxyethane derivative by reacting an epoxy compound with a carboxylate, carboxylic anhydride, carbonate or phenol compound, respectively, in the presence of the phosphine sulfide.

摘要翻译： 碱性且可溶于有机溶剂的有机化合物在制备或处理中没有问题，并且表现出作为碱性化合物的催化活性，即由式（1）表示的硫化膦及其制备方法，即 制备由式（1）表示的硫化膦，通过使一分子的硫代磷酰氯与由式（2）表示的三价分子的三分子反应。 所述硫化膦可用于通过在硫化膦或硫化氢存在下聚合烯化氧和选自水和具有部分结构的有机化合物的活性氢化合物来有效制造聚（环氧烷）的方法 的-OH或-NH-; 和2）由环氧化合物制造1,2-二氧乙烷衍生物的方法，即分别通过使环氧化合物与羧酸酯，羧酸酐，碳酸酯或酚化合物反应制备1,2-二氧乙烷衍生物 硫化磷的存在。