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公开(公告)号：US20230114648A1
公开(公告)日：2023-04-13
申请号：US18073632
申请日：2022-12-02
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A61K9/00 , A23L33/00 , A23L33/10 , A23L33/17 , A23L33/115
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US20140200266A1
公开(公告)日：2014-07-17
申请号：US14152267
申请日：2014-01-10
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353
CPC分类号： A61K31/353 , A23L33/10 , A23L33/115 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K9/0029
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
摘要翻译： 含单宁的组合物和使用它们的方法在简化的营养喂养期间增强或维持免疫功能。 提供药物组合物，包括肠内营养组合物。 组合物包含这样的单宁，如原花青素和/或可水解的单宁。 将单宁管理到接受简化营养的受试者的胃肠道，例如用肠内营养治疗或肠外营养治疗，可以减轻或预防对于简化营养时会出现的对胃肠道免疫系统的有害影响。
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公开(公告)号：US10105345B2
公开(公告)日：2018-10-23
申请号：US15347204
申请日：2016-11-09
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A61K9/00 , A23L33/00 , A23L33/10 , A23L33/17 , A23L33/115
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US11559511B2
公开(公告)日：2023-01-24
申请号：US17111948
申请日：2020-12-04
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A61K9/00 , A23L33/00 , A23L33/10 , A23L33/17 , A23L33/115
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US20180353465A1
公开(公告)日：2018-12-13
申请号：US16102844
申请日：2018-08-14
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A23L33/115 , A23L33/17 , A61K9/00 , A23L33/00 , A23L33/10
CPC分类号： A61K31/353 , A23L33/10 , A23L33/115 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K9/0029
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US09522131B2
公开(公告)日：2016-12-20
申请号：US14152267
申请日：2014-01-10
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A23L1/29 , A61K9/00
CPC分类号： A61K31/353 , A23L33/10 , A23L33/115 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K9/0029
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
摘要翻译： 含单宁的组合物和使用它们的方法在简化的营养喂养期间增强或维持免疫功能。 提供药物组合物，包括肠内营养组合物。 组合物包含这样的单宁，如原花青素和/或可水解的单宁。 将单宁管理到接受简化营养的受试者的胃肠道，例如用肠内营养治疗或肠外营养治疗，可以减轻或预防对于简化营养时会出现的对胃肠道免疫系统的有害影响。
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公开(公告)号：US20210085641A1
公开(公告)日：2021-03-25
申请号：US17111948
申请日：2020-12-04
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A61K9/00 , A23L33/00 , A23L33/10 , A23L33/17 , A23L33/115
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US10881635B2
公开(公告)日：2021-01-05
申请号：US16102844
申请日：2018-08-14
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A61K9/00 , A23L33/00 , A23L33/10 , A23L33/17 , A23L33/115
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
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公开(公告)号：US20170056369A1
公开(公告)日：2017-03-02
申请号：US15347204
申请日：2016-11-09
发明人： Jess Dreher Reed , Dhanansayan Shanmuganayagam , Christian Gerald Krueger , Kenneth Allan Kudsk , Joseph Francis Pierre , Aaron F. Heneghan , Rodrigo P. Feliciano
IPC分类号： A61K31/353 , A23L33/10 , A23L33/17 , A23L33/115 , A61K9/00 , A23L33/00
CPC分类号： A61K31/353 , A23L33/10 , A23L33/115 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K9/0029
摘要： Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
摘要翻译： 含单宁的组合物和使用它们的方法在简化的营养喂养期间增强或维持免疫功能。 提供药物组合物，包括肠内营养组合物。 组合物包含这样的单宁，如原花青素和/或可水解的单宁。 将单宁管理到接受简化营养的受试者的胃肠道，例如用肠内营养治疗或肠外营养治疗，可以减轻或预防对于简化营养时会出现的对胃肠道免疫系统的有害影响。
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