公开(公告)号：US20110178441A1

公开(公告)日：2011-07-21

申请号：US13003853

申请日：2009-07-14

Applicant: William James P. Tyler

Inventor： William James P. Tyler

IPC: A61N7/00

CPC classification number: A61N7/00 ,  A61B5/0476 ,  A61B5/4836 ,  A61N5/0613 ,  A61N5/062 ,  A61N5/0622 ,  A61N2005/0651 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/067 ,  A61N2007/0021 ,  A61N2007/0026 ,  A61N2007/0073 ,  A61N2007/0078 ,  C12N5/0619 ,  C12N13/00

Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.

Abstract translation: 本发明包括用于调节活细胞的活性或活性的方法和装置，例如在人，动物，植物，昆虫，微生物和其他生物体中发现或衍生的细胞。 本发明的方法包括使用超声波（例如低强度，低频超声波）对活细胞的应用来影响细胞并调节细胞的活性。 本发明的装置包括用于产生超声波的一个或多个部件，例如超声波发射器，换能器或压电换能器，复合换能器，CMUT，并且其可被提供为单个或多个换能器或阵列配置。 超声波可以是任何形状，并且可以被聚焦或未被聚焦。

公开(公告)号：US08591419B2

公开(公告)日：2013-11-26

申请号：US13003853

申请日：2009-07-14

Applicant: William James P. Tyler

Inventor： William James P. Tyler

IPC: A61B8/00

CPC classification number: A61N7/00 ,  A61B5/0476 ,  A61B5/4836 ,  A61N5/0613 ,  A61N5/062 ,  A61N5/0622 ,  A61N2005/0651 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/067 ,  A61N2007/0021 ,  A61N2007/0026 ,  A61N2007/0073 ,  A61N2007/0078 ,  C12N5/0619 ,  C12N13/00

Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.

Abstract translation: 本发明包括用于调节活细胞的活性或活性的方法和装置，例如在人，动物，植物，昆虫，微生物和其他生物体中发现或衍生的细胞。 本发明的方法包括使用超声波（例如低强度，低频超声波）对活细胞的应用来影响细胞并调节细胞的活性。 本发明的装置包括用于产生超声波的一个或多个部件，例如超声波发射器，换能器或压电换能器，复合换能器，CMUT，并且其可被提供为单个或多个换能器或阵列配置。 超声波可以是任何形状，并且可以被聚焦或未被聚焦。