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公开(公告)号：US10125148B2
公开(公告)日：2018-11-13
申请号：US15119475
申请日：2014-02-19
发明人： Timothy P. Connolly , Stanley D'Andrea , John F. Kadow , David R. Langley , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Michael A. Walker , Zhongyu Wang , Zhizhen Barbara Zheng
IPC分类号： C07D498/16 , C07D498/22 , A61K31/519 , A61K45/06
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US09938271B2
公开(公告)日：2018-04-10
申请号：US15119465
申请日：2015-02-13
IPC分类号： C07D471/04 , C07D498/22
CPC分类号： C07D471/04 , C07D498/22
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US09663536B2
公开(公告)日：2017-05-30
申请号：US14769646
申请日：2014-03-10
发明人： B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Zhongyu Wang
IPC分类号： C07D498/22 , A61K31/529 , C07D487/04 , C07D498/18 , C07D513/22 , C07D515/22 , A61K45/06
CPC分类号： C07D498/22 , A61K31/529 , A61K45/06 , C07D487/04 , C07D498/18 , C07D513/22 , C07D515/22
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection. Formule (I).
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公开(公告)号：US09932356B2
公开(公告)日：2018-04-03
申请号：US15115758
申请日：2015-02-10
IPC分类号： C07D513/22 , C07D498/22 , C07D471/22
CPC分类号： C07D513/22 , C07D471/22 , C07D498/22
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US09834566B2
公开(公告)日：2017-12-05
申请号：US15119431
申请日：2015-02-13
发明人： John F. Kadow , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Tao Wang , Zhiwei Yin , Zhongxing Zhang
IPC分类号： C07D498/16 , C07D498/22 , A61K31/519 , A61K45/06
CPC分类号： C07D498/16 , A61K31/519 , A61K45/06 , C07D498/22
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US10138253B2
公开(公告)日：2018-11-27
申请号：US15749158
申请日：2016-08-10
发明人： John F. Kadow , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Zhongyu Wang
IPC分类号： C07D471/04 , C07D498/22 , A61K31/437 , C07D498/16 , C07D498/06 , A61P31/18 , A61K31/4985
摘要： Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
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![Imidazo[1,2-A]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication](/abs-image/US/2018/09/04/US10065953B2/abs.jpg.150x150.jpg)
7.发明授权公开(公告)号：US10065953B2
公开(公告)日：2018-09-04
申请号：US15505955
申请日：2015-08-25
IPC分类号： C07D401/02 , C07D401/10 , A61K31/4353 , A61K31/437 , C07D471/04 , A61P31/18 , C07D519/00
CPC分类号： C07D471/04 , A61P31/18 , C07D519/00
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US09655889B2
公开(公告)日：2017-05-23
申请号：US14770702
申请日：2014-03-10
发明人： Kevin Peese , Zhongyu Wang , John F. Kadow , B. Narasimhulu Naidu
IPC分类号： C07D401/02 , C07D401/10 , A61K31/437 , A61K31/4353 , A61K31/4545 , C07D471/04 , A61K45/06
CPC分类号： A61K31/4545 , A61K45/06 , C07D471/04
摘要： The disclosure generally relates to compounds of formula (I), including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US09580431B2
公开(公告)日：2017-02-28
申请号：US14772146
申请日：2014-03-10
发明人： B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Zhongyu Wang
IPC分类号： C07D487/04 , A61K31/519 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
摘要翻译： 本公开一般涉及式I化合物，包括用于治疗人类免疫缺陷病毒（HIV）感染的组合物和方法。 本公开提供了HIV的新型抑制剂，含有这些化合物的药物组合物，以及使用这些化合物治疗HIV感染的方法。
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