- 专利标题： Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
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申请号： US15119431申请日： 2015-02-13
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公开(公告)号： US09834566B2公开(公告)日： 2017-12-05
- 发明人: John F. Kadow , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Tao Wang , Zhiwei Yin , Zhongxing Zhang
- 申请人： VIIV HEALTHCARE UK (NO.5) LIMITED
- 申请人地址： GB Brentford, Middlesex
- 专利权人： ViiV HEALTHCARE UK (NO.5) LIMITED
- 当前专利权人： ViiV HEALTHCARE UK (NO.5) LIMITED
- 当前专利权人地址： GB Brentford, Middlesex
- 代理商 Robert H. Brink; Edward R. Gimmi; William R. Majarian
- 国际申请： PCT/US2015/015758 WO 20150213
- 国际公布： WO2015/126743 WO 20150827
- 主分类号： C07D498/16
- IPC分类号： C07D498/16 ; C07D498/22 ; A61K31/519 ; A61K45/06
摘要：
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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