公开(公告)号：US08815866B2

公开(公告)日：2014-08-26

申请号：US13737173

申请日：2013-01-09

Applicant: Vertex Pharmaceuticals Incorporated

Inventor： Francois Maltais ,  Guy W. Bemis ,  Tiansheng Wang ,  Juan-Miguel Jimenez ,  Luca Settimo ,  Stephen Young ,  Dean Boyall ,  Damien Fraysse ,  Christopher John Davis

IPC: A61K31/497 ,  C07D401/00

CPC classification number: C07D417/14 ,  C07D213/73 ,  C07D213/74 ,  C07D401/04 ,  C07D401/10 ,  C07D401/14 ,  C07D407/04 ,  C07D407/12

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract translation: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。 本发明还提供了制备本发明化合物的方法。

公开(公告)号：US20130137703A1

公开(公告)日：2013-05-30

申请号：US13737173

申请日：2013-01-09

Applicant: Vertex Pharmaceuticals Incorporated

Inventor： Francois Maltais ,  Guy W. Bemis ,  Tiansheng Wang ,  Juan-Miguel Jimenez ,  Luca Settimo ,  Stephen Young ,  Dean Boyall ,  Damien Fraysse ,  Christopher John Davis

IPC: C07D417/14 ,  C07D401/14 ,  C07D401/10

CPC classification number: C07D417/14 ,  C07D213/73 ,  C07D213/74 ,  C07D401/04 ,  C07D401/10 ,  C07D401/14 ,  C07D407/04 ,  C07D407/12

Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

Abstract translation: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病，病症或病症的方法。 本发明还提供了制备本发明化合物的方法。