公开(公告)号：US20240302317A1

公开(公告)日：2024-09-12

申请号：US18261325

申请日：2022-01-13

申请人： VIREX HEALTH, INC.

发明人： Mark William Grinstaff ,  Scott Edward Schaus ,  Jane P. Bearinger ,  Augustus Lang ,  Ziad Al-Shamsie ,  Dylann Ceriani

IPC分类号： G01N27/327 ,  C12Q1/00 ,  G01N33/569 ,  G01N33/68 ,  G01N33/74

CPC分类号： G01N27/3275 ,  C12Q1/005 ,  G01N27/3271 ,  G01N33/56983 ,  G01N33/6869 ,  G01N33/74 ,  G01N2333/165 ,  G01N2333/5412 ,  G01N2333/5756 ,  G01N2469/10

摘要： The strip systems, methods, devices and associated kits disclosed herein are used to determine the presence and/or level a target analyte(s) in sample (e.g., a biological sample such as saliva or nasal swab) wherein the target analyte(s) may be a microorganism (e.g., a whole virus) or molecule (e.g., a viral antigen) associated with a healthy state, disease or injury or otherwise altered physiological condition. In certain embodiments, the systems, methods, devices and kits provide one or more improved properties relative to the lateral flow protein and other assays known in the art for the detection, including but not limited to, assay time, ease of use, risk of infection, accuracy, specificity, selectivity, limit of detection of the assay, quantitative detection and the effect of common interferents to the sensor output, cost, simplicity or a combination thereof. In certain embodiments, the systems, assays, methods and kids are multiplexed, i.e., permit detection or monitoring of more than one target analyte (e.g., two different viruses or a virus and a bacterium).