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公开(公告)号：US20230355626A1
公开(公告)日：2023-11-09
申请号：US17802194
申请日：2021-03-03
发明人： Eric P. GILLIS , Christiana IWUAGWU
IPC分类号： A61K31/519 , C07D471/04 , A61K31/5365 , A61K31/537 , A61K31/513 , A61K31/675 , A61K31/4985 , A61K31/54 , A61K45/06 , A61P31/18
CPC分类号： A61K31/519 , C07D471/04 , A61K31/5365 , A61K31/537 , A61K31/513 , A61K31/675 , A61K31/4985 , A61K31/54 , A61K45/06 , A61P31/18
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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2.发明申请公开(公告)号：US20210024503A1
公开(公告)日：2021-01-28
申请号：US17042413
申请日：2019-04-11
发明人： Makonen BELEMA , John A. BENDER , David B. FRENNESSON , Eric P. GILLIS , Christiana IWUAGWU , John F. KADOW , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Kevin M. PEESE , Ramkumar RAJAMANI , Mark G. SAULNIER , Alan Xiangdong WANG , Manoj PATEL , Michael S. BOWSHER
IPC分类号： C07D403/14 , A61P31/18 , C07D403/12 , C07D401/14 , C07D405/14 , C07D413/14 , C07D491/052
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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公开(公告)号：US20210395248A1
公开(公告)日：2021-12-23
申请号：US17287736
申请日：2019-11-04
IPC分类号： C07D471/04 , C07D519/00 , A61P31/18
摘要： Compounds of Formula I, and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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![PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION](/abs-image/US/2021/10/21/US20210323967A1/abs.jpg.150x150.jpg)
4.发明申请公开(公告)号：US20210323967A1
公开(公告)日：2021-10-21
申请号：US17268107
申请日：2020-06-17
发明人： Eric P. GILLIS , Christiana IWUAGWU
IPC分类号： C07D487/04 , A61K45/06 , A61P31/18 , A61K9/00
摘要： The compound and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.
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公开(公告)号：US20220389007A1
公开(公告)日：2022-12-08
申请号：US17763133
申请日：2020-09-29
发明人： Michael S. BOWSHER , Eric P. GILLIS , Christiana IWUAGWU , B Narasimhulu NAIDU , Kyle E. PARCELLA , Manoj PATEL
IPC分类号： C07D471/04 , C07D277/08 , A61P31/18
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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公开(公告)号：US20210403465A1
公开(公告)日：2021-12-30
申请号：US17285680
申请日：2019-10-28
IPC分类号： C07D417/14 , C07D403/14 , C07D405/14 , C07D401/14
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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7.发明申请公开(公告)号：US20200016136A1
公开(公告)日：2020-01-16
申请号：US16465622
申请日：2018-01-02
发明人： Michael S. BOWSHER , Jeffrey DESKUS , Kyle J. EASTMAN , Eric P. GILLIS , David B. FRENNESSON , Christiana IWUAGWU , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Kevin M. PEESE , Mark G. SAULNIER , Prasanna SIVAPRAKASAM
IPC分类号： A61K31/444 , C07D401/14 , C07D413/14 , C07D491/048 , C07D491/08 , A61K31/5377 , A61K31/506 , A61K31/519 , A61K31/497 , A61K31/5386 , A61K31/4995 , C07D471/08 , C07D417/14 , A61K31/541 , C07D491/147 , A61P31/18
摘要： Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
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公开(公告)号：US20210393633A1
公开(公告)日：2021-12-23
申请号：US17284855
申请日：2019-10-22
IPC分类号： A61K31/517 , A61K45/06 , C07D403/14 , C07D405/14 , C07D401/14 , A61K31/5377 , A61P31/18
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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公开(公告)号：US20210379071A1
公开(公告)日：2021-12-09
申请号：US17288085
申请日：2019-11-04
发明人： Michael S. BOWSHER , Eric P. GILLIS , Christiana IWUAGWU , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Manoj PATEL , Kevin M. PEESE
IPC分类号： A61K31/517 , A61K45/06 , C07D403/14 , C07D471/04 , A61P31/18 , A61K31/519
摘要： Compounds and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.
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公开(公告)号：US20230149408A1
公开(公告)日：2023-05-18
申请号：US17918654
申请日：2021-04-13
IPC分类号： A61K31/519 , A61K31/517 , A61K47/10 , A61K47/02
CPC分类号： A61K31/519 , A61K31/517 , A61K47/02 , A61K47/10
摘要： A pharmaceutical composition comprising the compound of Formula Ia, Formula Ib, Formula Ic, or Formula Id, or a pharmaceutically acceptable salt thereof, is set forth.
Formula Id
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