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1.
公开(公告)号:US20210024503A1
公开(公告)日:2021-01-28
申请号:US17042413
申请日:2019-04-11
发明人: Makonen BELEMA , John A. BENDER , David B. FRENNESSON , Eric P. GILLIS , Christiana IWUAGWU , John F. KADOW , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Kevin M. PEESE , Ramkumar RAJAMANI , Mark G. SAULNIER , Alan Xiangdong WANG , Manoj PATEL , Michael S. BOWSHER
IPC分类号: C07D403/14 , A61P31/18 , C07D403/12 , C07D401/14 , C07D405/14 , C07D413/14 , C07D491/052
摘要: Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth:
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2.
公开(公告)号:US20200016136A1
公开(公告)日:2020-01-16
申请号:US16465622
申请日:2018-01-02
发明人: Michael S. BOWSHER , Jeffrey DESKUS , Kyle J. EASTMAN , Eric P. GILLIS , David B. FRENNESSON , Christiana IWUAGWU , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Kevin M. PEESE , Mark G. SAULNIER , Prasanna SIVAPRAKASAM
IPC分类号: A61K31/444 , C07D401/14 , C07D413/14 , C07D491/048 , C07D491/08 , A61K31/5377 , A61K31/506 , A61K31/519 , A61K31/497 , A61K31/5386 , A61K31/4995 , C07D471/08 , C07D417/14 , A61K31/541 , C07D491/147 , A61P31/18
摘要: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
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3.
公开(公告)号:US20200055839A1
公开(公告)日:2020-02-20
申请号:US16465199
申请日:2018-01-02
发明人: Makonen BELEMA , Michael S. BOWSHER , Jeffrey A. DESKUS , Kyle J. EASTMAN , Eric P. GILLIS , David B. FRENNESSON , Christiana IWUAGWU , John F. KADOW , B. Narasimhulu NAIDU , Kyle E. PARCELLA , Kevin M. PEESE , Mark G. SAULNIER , Prasanna SIVAPRAKASAM
IPC分类号: C07D401/14 , C07D401/04 , C07D491/048 , C07D405/14 , C07D413/14 , A61P31/18
摘要: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
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