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1.发明授权公开(公告)号：US11185409B2
公开(公告)日：2021-11-30
申请号：US16455740
申请日：2019-06-27
申请人： VDyne, Inc.
摘要： The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular a side delivered transcatheter prosthetic heart valve having a collapsible inner flow control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.
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2.发明申请公开(公告)号：US20210315694A1
公开(公告)日：2021-10-14
申请号：US17222430
申请日：2021-04-05
申请人： VDyne, Inc.
摘要： The invention relates to a heart valve regurgitation drum and optional closure disk and/or tubular stent to manage and provide levels of intentional regurgitation within an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component/valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.
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3.发明申请公开(公告)号：US20210244533A1
公开(公告)日：2021-08-12
申请号：US17193946
申请日：2021-03-05
申请人： VDyne, Inc.
发明人： Robert Vidlund , Mark Christianson , Neelakantan Saikrishnan , Scott Kramer , Chad Ferrin , Lucas Harder , David Holtan , Craig Ekvall , Cameron Vidlund
IPC分类号： A61F2/24
摘要： A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.
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公开(公告)号：US20210220127A1
公开(公告)日：2021-07-22
申请号：US17221547
申请日：2021-04-02
申请人： VDyne, Inc.
IPC分类号： A61F2/24
摘要： A prosthetic heart valve includes a valve frame defining an aperture that extends along a central axis and a flow control component mounted within the aperture. The valve frame includes a distal anchoring element and a proximal anchoring element. The valve frame has a compressed configuration to allow the prosthetic heart valve to be delivered to a heart of a patient via a delivery catheter. The valve frame is configured to transition to an expanded configuration when released from the delivery catheter. The prosthetic heart valve is configured to be seated in a native annulus when the valve frame is in the expanded configuration. The distal and proximal anchoring elements configured to be inserted through the native annulus prior to seating the prosthetic heart valve. The proximal anchoring element is ready to be deployed subannularly or is optionally configured to be transitioned from a first configuration to a second configuration after the prosthetic valve is seated.
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5.发明申请公开(公告)号：US20210186693A1
公开(公告)日：2021-06-24
申请号：US17193936
申请日：2021-03-05
申请人： VDyne, Inc.
发明人： Robert VIDLUND, I , Mark Christianson , Neelakantan Saikrishnan , Scott Kramer , Chad Perrin , Lucas Harder , David Holtan , Craig Ekvall , Cameron Vidlund
IPC分类号： A61F2/24
摘要： A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.
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6.发明授权公开(公告)号：US11337807B2
公开(公告)日：2022-05-24
申请号：US17388983
申请日：2021-07-29
申请人： VDyne, Inc.
发明人： Mark Christianson , Robert Vidlund , Neelakantan Saikrishnan , Scott Kramer , Chad Perrin , Lucas Harder
IPC分类号： A61F2/24
摘要： A side-deliverable prosthetic heart valve includes an outer frame and a flow control component. The outer frame has a supra-annular region, a subannular region, and a transannular region therebetween. The flow control component is mounted to the outer frame such that at least a portion of the flow control component is disposed in the transannular region. The prosthetic valve has a delivery configuration for side-delivery via a delivery catheter and is expandable when the prosthetic valve is released from the delivery catheter. The subannular region of the outer frame is disposable in a first configuration as the prosthetic valve is seated in an annulus of a native heart valve and is transitionable to a second configuration after the prosthetic valve is seated in the annulus of the native heart valve.
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公开(公告)号：US11273033B2
公开(公告)日：2022-03-15
申请号：US16443862
申请日：2019-06-17
申请人： VDyne, Inc.
摘要： The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular a side delivered transcatheter prosthetic valve having a tubular frame with a flow control component mounted within the tubular frame and configured to permit blood flow in a first direction through an inflow end of the valve and block blood flow in a second direction, opposite the first direction, through an outflow end of the valve, wherein the valve is compressible to a compressed configuration for introduction into the body using a delivery catheter for implanting at a desired location in the body, said compressed configuration having a long-axis oriented at an intersecting angle of between 45-135 degrees to the first direction, and expandable to an expanded configuration having a long-axis oriented at an intersecting angle of between 45-135 degrees to the first direction, wherein the long-axis of the compressed configuration of the valve is substantially parallel to a length-wise cylindrical axis of the delivery catheter, and wherein the valve has a height of about 5-60 mm and a diameter of about 25-80 mm.
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8.发明授权公开(公告)号：US11179239B2
公开(公告)日：2021-11-23
申请号：US17193946
申请日：2021-03-05
申请人： VDyne, Inc.
发明人： Robert Vidlund , Mark Christianson , Neelakantan Saikrishnan , Scott Kramer , Lucas Harder , Craig Ekvall
IPC分类号： A61F2/24
摘要： A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.
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9.发明授权公开(公告)号：US11344412B2
公开(公告)日：2022-05-31
申请号：US17476215
申请日：2021-09-15
申请人： VDyne, Inc.
发明人： Robert Vidlund , Mark Christianson , Neelakantan Saikrishnan , Scott Kramer , Lucas Harder , David Holtan , Craig Ekvall , Cameron Vidlund
IPC分类号： A61F2/24
摘要： A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.
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10.发明授权公开(公告)号：US11331186B2
公开(公告)日：2022-05-17
申请号：US17167988
申请日：2021-02-04
申请人： VDyne, Inc.
发明人： Mark Christianson , Robert Vidlund , Neelakantan Saikrishnan , Scott Kramer , Chad Perrin , Lucas Harder
IPC分类号： A61F2/24
摘要： A side-deliverable prosthetic heart valve includes an outer frame and a flow control component. The outer frame has a supra-annular region, a subannular region, and a transannular region therebetween. The flow control component is mounted to the outer frame such that at least a portion of the flow control component is disposed in the transannular region. The prosthetic valve has a delivery configuration for side-delivery via a delivery catheter and is expandable when the prosthetic valve is released from the delivery catheter. The subannular region of the outer frame is disposable in a first configuration as the prosthetic valve is seated in an annulus of a native heart valve and is transitionable to a second configuration after the prosthetic valve is seated in the annulus of the native heart valve.
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