公开(公告)号：US11185409B2

公开(公告)日：2021-11-30

申请号：US16455740

申请日：2019-06-27

Applicant: VDyne, Inc.

Inventor： Mark Christianson ,  Robert Vidlund ,  Neelakantan Saikrishnan ,  Chad Perrin

IPC: A61F2/24 ,  B33Y80/00

Abstract: The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular a side delivered transcatheter prosthetic heart valve having a collapsible inner flow control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

公开(公告)号：US20210154011A1

公开(公告)日：2021-05-27

申请号：US17167983

申请日：2021-02-04

Applicant: VDyne, Inc.

Inventor： Mark CHRISTIANSON ,  Robert Vidlund ,  Neelakantan SAIKRISHNAN

IPC: A61F2/24

Abstract: A prosthetic valve includes a frame and a flow control component. The frame has an aperture extending through the frame about a central axis. The flow control component is mounted within the aperture and is configured to permit blood flow in a first direction approximately parallel to the vertical axis from an inflow end to an outflow end of the flow control component and to block blood flow in a second direction, opposite the first direction. The frame has an expanded configuration with a first height along the central axis, a first lateral width along a lateral axis perpendicular to the central axis, and a first longitudinal length along a longitudinal axis perpendicular to the central axis and the lateral axis. The frame has a compressed configuration with a second height less than the first height and a second lateral width less than the first lateral width.

公开(公告)号：US11344413B2

公开(公告)日：2022-05-31

申请号：US17167983

申请日：2021-02-04

Applicant: VDyne, Inc.

Inventor： Mark Christianson ,  Robert Vidlund ,  Neelakantan Saikrishnan

IPC: A61F2/24

Abstract: A prosthetic valve includes a frame and a flow control component. The frame has an aperture extending through the frame about a central axis. The flow control component is mounted within the aperture and is configured to permit blood flow in a first direction approximately parallel to the vertical axis from an inflow end to an outflow end of the flow control component and to block blood flow in a second direction, opposite the first direction. The frame has an expanded configuration with a first height along the central axis, a first lateral width along a lateral axis perpendicular to the central axis, and a first longitudinal length along a longitudinal axis perpendicular to the central axis and the lateral axis. The frame has a compressed configuration with a second height less than the first height and a second lateral width less than the first lateral width.

公开(公告)号：US20210290385A1

公开(公告)日：2021-09-23

申请号：US17207076

申请日：2021-03-19

Applicant: VDyne, Inc.

Inventor： Mark CHRISTIANSON ,  Robert Vidlund ,  Neelakantan Saikrishnan

IPC: A61F2/24

Abstract: Embodiments are described herein that relate to prosthetic heart valves, and devices and methods for use in the delivery and deployment of such valves.

公开(公告)号：US20210236280A1

公开(公告)日：2021-08-05

申请号：US17236219

申请日：2021-04-21

Applicant: VDyne, Inc.

Inventor： Mark CHRISTIANSON ,  Robert Vidlund ,  David Holtan ,  Lucas Harder

IPC: A61F2/24

Abstract: The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement (A61F2/2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

公开(公告)号：US11071627B2

公开(公告)日：2021-07-27

申请号：US16163577

申请日：2018-10-18

Applicant: VDyne, Inc.

Inventor： Neelakantan Saikrishnan ,  Mark Christianson ,  Robert Vidlund

IPC: A61F2/24

Abstract: The invention relates to a transcatheter heart valve replacement (A62F2/2412), and in particular an orthogonally delivered transcatheter prosthetic valve frame having a tubular frame for mounting a flow control component wherein the valve frame is compressible to a compressed configuration for sideways or lateral introduction into the body using a delivery catheter for implanting at a desired location in the body, where the compressed configuration has a long-axis oriented roughly perpendicular to the central axis of the native annulus, wherein the long-axis of the compressed configuration of the valve is substantially parallel to a length-wise cylindrical axis of the delivery catheter, and wherein the valve has a height of about 5-60 mm and a diameter of about 25-80 mm.

公开(公告)号：US20210137677A1

公开(公告)日：2021-05-13

申请号：US17154227

申请日：2021-01-21

Applicant: VDyne, Inc.

Inventor： Mark CHRISTIANSON ,  Robert Vidlund ,  Scott Kramer

IPC: A61F2/24

Abstract: A side-deliverable prosthetic valve includes an outer frame, a flow control component mounted within the outer frame, and an anchoring element coupled to a distal side of the outer frame. The prosthetic valve is foldable along a longitudinal axis and compressible along a central axis to a compressed configuration for side delivery via a delivery catheter and is expandable to an expanded configuration when released from the delivery catheter. An end portion of the anchoring element is configured to engage a guide wire. The anchoring element is extended during deployment to allow the anchoring element to capture at least one of native leaflet or chordae and, in response to the guide wire being disengaged from the end portion, transitions to a folded configuration to secure at least one of the native leaflet or the chordae between the anchoring element and the distal side of the outer frame.

公开(公告)号：US12150852B2

公开(公告)日：2024-11-26

申请号：US17666086

申请日：2022-02-07

Applicant: VDyne, Inc.

Inventor： Robert Vidlund ,  Mark Christianson ,  Neelakantan Saikrishnan ,  Scott Kramer

IPC: A61F2/24

Abstract: A prosthetic heart valve includes a valve frame defining an aperture that extends along a central axis and a flow control component mounted within the aperture. The valve frame includes a distal anchoring element and a proximal anchoring element. The valve frame has a compressed configuration to allow the valve to be delivered to a heart of a patient via a delivery catheter. The valve frame is configured to transition to an expanded configuration when released from the delivery catheter. The valve is configured to be seated in a native annulus when the valve frame is in the expanded configuration. The distal and proximal anchoring elements configured to be inserted through the native annulus prior to seating the valve. The proximal anchoring element is ready to be deployed subannularly or is optionally configured to be transitioned from a first configuration to a second configuration after the valve is seated.

公开(公告)号：US20240148496A1

公开(公告)日：2024-05-09

申请号：US18329098

申请日：2023-06-05

Applicant: VDyne, Inc.

Inventor： Mark CHRISTIANSON ,  Robert Vidlund ,  David Holtan ,  Lucas Harder

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2439 ,  A61F2220/0008

Abstract: The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement, and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

公开(公告)号：US11712335B2

公开(公告)日：2023-08-01

申请号：US17550400

申请日：2021-12-14

Applicant: VDyne, Inc.

Inventor： Mark Christianson ,  Robert Vidlund ,  David Holtan ,  Lucas Harder

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2439 ,  A61F2220/0008

Abstract: The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement (A61F2/2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.