公开(公告)号：US20180194742A1

公开(公告)日：2018-07-12

申请号：US15836675

申请日：2017-12-08

申请人： University of Kentucky Research Foundation

发明人： Sylvie Garneau-Tsodikova ,  Sanjib K. Shrestha ,  Atefeh Garzan ,  Nishad Thamban Chandrika

IPC分类号： C07D249/08 ,  A61P31/10 ,  A01N43/653 ,  C07D405/06 ,  C07D295/03 ,  A01N43/60 ,  A01N43/84 ,  C07D403/06 ,  C07C271/16 ,  A01N47/12 ,  C07C217/08 ,  A01N33/08

CPC分类号： C07D249/08 ,  A01N33/08 ,  A01N43/60 ,  A01N43/653 ,  A01N43/84 ,  A01N47/12 ,  A61P31/10 ,  C07C217/08 ,  C07C271/16 ,  C07D295/03 ,  C07D403/06 ,  C07D405/06

摘要： Compounds and compositions having antifungal activity, and methods of using the antifungal compounds and compositions, are described for use in treating fungal infections.

公开(公告)号：US12103916B2

公开(公告)日：2024-10-01

申请号：US15836675

申请日：2017-12-08

申请人： University of Kentucky Research Foundation

发明人： Sylvie Garneau-Tsodikova ,  Sanjib K Shrestha ,  Atefeh Garzan ,  Nishad Thamban Chandrika

IPC分类号： C07D249/08 ,  A01N33/08 ,  A01N43/60 ,  A01N43/653 ,  A01N43/84 ,  A01N47/12 ,  A61P31/10 ,  C07C217/08 ,  C07C271/16 ,  C07D295/03 ,  C07D403/06 ,  C07D405/06

CPC分类号： C07D249/08 ,  A01N33/08 ,  A01N43/60 ,  A01N43/653 ,  A01N43/84 ,  A01N47/12 ,  A61P31/10 ,  C07C217/08 ,  C07C271/16 ,  C07D295/03 ,  C07D403/06 ,  C07D405/06

摘要： Compounds and compositions having antifungal activity, and methods of using the antifungal compounds and compositions, are described for use in treating fungal infections.

公开(公告)号：US11851391B2

公开(公告)日：2023-12-26

申请号：US16514276

申请日：2019-07-17

申请人： University of Kentucky Research Foundation

发明人： Sylvie Garneau-Tsodikova ,  David S. Watt ,  Nishad Thamban Chandrika

IPC分类号： C07C281/18 ,  C07C243/10 ,  A61P31/10 ,  C07C277/00

CPC分类号： C07C243/10 ,  A61P31/10 ,  C07C277/00

摘要： An antifungal composition and a method of treating a systemic fungal infection are provided herein. The antifungal composition includes a diaryl bishydrazone. The method includes administering a therapeutically effective amount of the diaryl bishydrazone to a subject in need thereof.

公开(公告)号：US20200024224A1

公开(公告)日：2020-01-23

申请号：US16514276

申请日：2019-07-17

申请人： University of Kentucky Research Foundation

发明人： Sylvie Garneau-Tsodikova ,  David S. Watt ,  Nishad Thamban Chandrika

IPC分类号： C07C243/10 ,  C07C277/00 ,  A61P31/10

摘要： An antifungal composition and a method of treating a systemic fungal infection are provided herein. The antifungal composition includes a diaryl bishydrazone. The method includes administering a therapeutically effective amount of the diaryl bishydrazone to a subject in need thereof.