公开(公告)号：US20220305069A1

公开(公告)日：2022-09-29

申请号：US17431145

申请日：2020-09-11

Applicant: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY

Inventor： LIANZHONG AI ,  YONGJUN XIA ,  PENG MENG ,  HUI ZHANG ,  GUANGQIANG WANG ,  ZHIQIANG XIONG ,  XIN SONG

IPC: A61K36/07 ,  A23L33/21 ,  A23L31/00 ,  B01D11/02 ,  A61P3/06

Abstract: A preparation method of Antrodia cinnamomea water-insoluble dietary fiber. After ethanol and water extraction, Antrodia cinnamomea wastes are dried and superfine-comminuted to obtain Antrodia cinnamomea waste powder. The waste powder treated with NaOH solution containing NaBH4 is extracted it twice to obtain two extracts. The two extracts are combined and an appropriate amount of glacial acetic acid are added for neutralization. The extracts are centrifugalized and precipitate is collected. After washing the precipitate with ultrapure water, the precipitate is dissolved with LiCl-DMSO. The precipitate that is insoluble in the LiCl-DMSO solution is dialyzed and freeze-dried to obtain the water-insoluble dietary fiber component ACA-IDK of Antrodia cinnamomea. The LiCl-DMSO solution is subjected to ethanol/DMSO fractional precipitation, and then the precipitate is collected and dialyzed. The water-insoluble dietary fiber component ACA-DK of Antrodia cinnamomea is obtained after freeze-drying.