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公开(公告)号：US10369353B2
公开(公告)日：2019-08-06
申请号：US12359037
申请日：2009-01-23
申请人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
发明人： Jonathon E. Giftakis , Nina M. Graves , Jonathan C. Werder , Eric J. Panken , Timothy J. Denison , Keith A. Miesel , Michele H. Herzog
摘要： Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.
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公开(公告)号：US09717846B2
公开(公告)日：2017-08-01
申请号：US13561706
申请日：2012-07-30
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/4836 , A61B2562/0219 , A61M2005/14208 , A61M2205/17 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2210/1089 , A61M2230/62 , A61N1/3605 , A61N1/37247
摘要： Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
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公开(公告)号：US09327117B2
公开(公告)日：2016-05-03
申请号：US13264023
申请日：2010-04-20
CPC分类号： A61N1/36007 , A61B5/053 , A61B5/1116 , A61B5/204 , A61B5/686 , A61B5/6883 , A61B5/7203 , A61B2560/0462 , A61B2562/0219
摘要： This disclosure provides techniques for bladder sensing. In accordance with the techniques described in this disclosure, a device may measure the impedance of a bladder, determine the posture of a patient, and determine a status of the bladder based on the impedance and posture.
摘要翻译： 本公开提供了用于膀胱感测的技术。 根据本公开中描述的技术，装置可以测量膀胱的阻抗，确定患者的姿势，并且基于阻抗和姿势来确定膀胱的状态。
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公开(公告)号：US08397578B2
公开(公告)日：2013-03-19
申请号：US12793459
申请日：2010-06-03
CPC分类号： G01L9/0072 , G01L19/142 , G01L19/143 , G01L19/147 , H01L2224/48472 , Y10T29/49002 , Y10T29/53265
摘要： The disclosure is directed to a capacitive pressure sensor, and the assembly of a capacitive pressure sensor, that may be used within an implantable medical pump. In one example, a housing ferrule that encloses one capacitive plate and includes at least one protrusion for attaching a support structure of the capacitive plate. The at least one protrusion defines a smaller inner diameter as a reference point for securing the support structure while the ferrule provides a larger inner diameter to allow the support structure to tilt inside the ferrule to orient the capacitive plate into a desired plane. Despite manufacturing irregularities, the capacitive plate can be mounted in the desired plane parallel to another capacitive plate, a diaphragm, mounted to an edge of the ferrule. In another example, an assembly tool provides a stage to orient the capacitive plate and support structure within the ferrule at a desired depth.
摘要翻译： 本公开涉及电容式压力传感器以及可在可植入医疗泵内使用的电容式压力传感器的组件。 在一个示例中，壳体套圈包围一个电容板并且包括用于附接电容板的支撑结构的至少一个突起。 所述至少一个突出部限定较小的内径作为用于固定支撑结构的参考点，同时套圈提供更大的内径以允许支撑结构在套圈内部倾斜以将电容板定向到期望的平面。 尽管制造不规则，但是电容板可以安装在平行于另一个电容板的所需平面中，该电容板安装在套圈的边缘上。 在另一示例中，组装工具提供了将电容板和支撑结构定位在套圈内的阶段，以期望的深度。
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公开(公告)号：US20120296236A1
公开(公告)日：2012-11-22
申请号：US13561706
申请日：2012-07-30
IPC分类号： A61B5/11
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/4836 , A61B2562/0219 , A61M2005/14208 , A61M2205/17 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2210/1089 , A61M2230/62 , A61N1/3605 , A61N1/37247
摘要： Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
摘要翻译： 姿态反应治疗由医疗系统基于在任何给定时间仅从多个姿势传感器中的一个输入的姿势状态来传送。 示例性可植入医疗系统包括第一姿态传感器和第二传感器。 处理器基于基于仅从第一或第二姿态传感器中的一个输入确定的患者姿势状态或患者活动水平中的至少一个来控制对患者的治疗递送。 在一些示例中，使用植入式姿势响应医疗系统的多个姿势传感器中的一个来自动地重新定向已经变得迷失方向的另一姿态传感器（该系统）。 错位姿态传感器可以一次自动地重新定向一个或多个姿势状态。
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公开(公告)号：US08231555B2
公开(公告)日：2012-07-31
申请号：US12433442
申请日：2009-04-30
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/4836 , A61B2562/0219 , A61M2005/14208 , A61M2205/17 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2210/1089 , A61M2230/62 , A61N1/3605 , A61N1/37247
摘要： Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
摘要翻译： 姿态反应治疗由医疗系统基于在任何给定时间仅从多个姿势传感器中的一个输入的姿势状态来传送。 示例性可植入医疗系统包括第一姿态传感器和第二传感器。 处理器基于基于仅从第一或第二姿态传感器中的一个输入确定的患者姿势状态或患者活动水平中的至少一个来控制对患者的治疗递送。 在一些示例中，使用植入式姿势响应医疗系统的多个姿势传感器中的一个来自动地重新定向已经变得迷失方向的另一姿态传感器（该系统）。 错位姿态传感器可以一次自动地重新定向一个或多个姿势状态。
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公开(公告)号：US20110296925A1
公开(公告)日：2011-12-08
申请号：US12793459
申请日：2010-06-03
CPC分类号： G01L9/0072 , G01L19/142 , G01L19/143 , G01L19/147 , H01L2224/48472 , Y10T29/49002 , Y10T29/53265
摘要： The disclosure is directed to a capacitive pressure sensor, and the assembly of a capacitive pressure sensor, that may be used within an implantable medical pump. In one example, a housing ferrule that encloses one capacitive plate and includes at least one protrusion for attaching a support structure of the capacitive plate. The at least one protrusion defines a smaller inner diameter as a reference point for securing the support structure while the ferrule provides a larger inner diameter to allow the support structure to tilt inside the ferrule to orient the capacitive plate into a desired plane. Despite manufacturing irregularities, the capacitive plate can be mounted in the desired plane parallel to another capacitive plate, a diaphragm, mounted to an edge of the ferrule. In another example, an assembly tool provides a stage to orient the capacitive plate and support structure within the ferrule at a desired depth.
摘要翻译： 本公开涉及电容式压力传感器以及可在可植入医疗泵内使用的电容式压力传感器的组件。 在一个示例中，壳体套圈包围一个电容板并且包括用于附接电容板的支撑结构的至少一个突起。 所述至少一个突出部限定较小的内径作为用于固定支撑结构的参考点，同时套圈提供更大的内径以允许支撑结构在套圈内部倾斜以将电容板定向到期望的平面。 尽管制造不规则，但是电容板可以安装在平行于另一个电容板的所需平面中，该电容板安装在套圈的边缘上。 在另一示例中，组装工具提供了将电容板和支撑结构定位在套圈内的阶段，以期望的深度。
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公开(公告)号：US20100280578A1
公开(公告)日：2010-11-04
申请号：US12433588
申请日：2009-04-30
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/4836 , A61B2562/0219 , A61M2005/14208 , A61M2205/17 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2210/1089 , A61M2230/62 , A61N1/3605 , A61N1/37247
摘要： Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
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公开(公告)号：US20100280417A1
公开(公告)日：2010-11-04
申请号：US12433442
申请日：2009-04-30
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/4836 , A61B2562/0219 , A61M2005/14208 , A61M2205/17 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2210/1089 , A61M2230/62 , A61N1/3605 , A61N1/37247
摘要： Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time.
摘要翻译： 姿态反应治疗由医疗系统基于在任何给定时间仅从多个姿势传感器中的一个输入的姿势状态来传送。 示例性可植入医疗系统包括第一姿态传感器和第二传感器。 处理器基于基于仅从第一或第二姿态传感器中的一个输入确定的患者姿势状态或患者活动水平中的至少一个来控制对患者的治疗递送。 在一些示例中，使用植入式姿势响应医疗系统的多个姿势传感器中的一个来自动地重新定向已经变得迷失方向的另一姿态传感器（该系统）。 错位姿态传感器可以一次自动地重新定向一个或多个姿势状态。
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公开(公告)号：US08554325B2
公开(公告)日：2013-10-08
申请号：US13345397
申请日：2012-01-06
申请人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
发明人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
IPC分类号： A61N1/18
CPC分类号： A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
摘要翻译： 基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。 在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。 运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。 在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。 在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。 此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。
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