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公开(公告)号：US12275927B2
公开(公告)日：2025-04-15
申请号：US17737170
申请日：2022-05-05
Applicant: The Regents of the University of California
Inventor： John D. Coates , Ouwei Wang , Victor M. Reyes-Umana
Abstract: Biomanufacturing hygiene control in batch and fed-batch bioreactors is provided using a bioreactor employing a chlorite/Cld system, wherein the bioreactor comprises an engineered cultured cell expressing a recombinant cytoplasmic chlorite dismutase (cCld) sufficient to increase chlorite resistance of the cell, and chlorite sufficient to substantially inhibit growth of one or more contaminating microorganisms in the bioreactor yet not substantially inhibit growth of the cell.
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2.发明授权公开(公告)号：US09994758B2
公开(公告)日：2018-06-12
申请号：US15160680
申请日：2016-05-20
Applicant: The Regents of the University of California
Inventor： John D. Coates
IPC: C09K8/532 , C07K14/195 , C12N1/00 , C12N9/99
CPC classification number: C09K8/532 , C07K14/195 , C09K2208/20 , C12N1/00 , C12N9/99
Abstract: The present disclosure relates to methods of controlling the sulfide (S2−) content in systems, such as oil and gas reservoirs and pipelines, by the use of chlorine oxyanions and microorganisms with (per)chlorate-reducing activity.
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Patent Agency Ranking
公开(公告)号：US20220259544A1
公开(公告)日：2022-08-18
申请号：US17737170
申请日：2022-05-05
Applicant: The Regents of the University of California
Inventor： John D. Coates , Ouwei Wang , Victor M. Reyes-Umana
Abstract: Biomanufacturing hygiene control in batch and fed-batch bioreactors is provided using a bioreactor employing a chlorite/Cld system, wherein the bioreactor comprises an engineered cultured cell expressing a recombinant cytoplasmic chlorite dismutase (cCld) sufficient to increase chlorite resistance of the cell, and chlorite sufficient to substantially inhibit growth of one or more contaminating microorganisms in the bioreactor yet not substantially inhibit growth of the cell.
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公开(公告)号：US09708526B2
公开(公告)日：2017-07-18
申请号：US14353267
申请日：2012-10-24
Applicant: The Regents of the University of California
Inventor： John D. Coates
Abstract: Methods of reversibly altering the rock hydrology in systems, such as oil reservoirs, by inducing authigenic mineral-precipitating bacteria to produce authigenic rock mineral.
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公开(公告)号：US20230272404A1
公开(公告)日：2023-08-31
申请号：US18313367
申请日：2023-05-07
Applicant: The Regents of the University of California
Inventor： John D. Coates
CPC classification number: C12N15/52 , C12Y197/01001 , C12Y113/11049 , C12Y107/02001 , C12Y108/05003 , C12P7/625
Abstract: Aerobic microbial processes comprise culturing microbes comprising a (per)chlorate respiration pathway in a bioreactor in a bioprocess employing microbial respiration of chloroxyanions as a source of oxygen for the bioprocess, in the absence of external addition of molecular oxygen.
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公开(公告)号：US10724010B2
公开(公告)日：2020-07-28
申请号：US15101267
申请日：2014-12-05
Applicant: The Regents of the University of California
Inventor： John D. Coates
Abstract: The present disclosure relates to recombinantly engineered cells that contain a chlorite dismutase polypeptide and methods for culturing such cells in a culture medium containing chlorite in an amount sufficient to reduce the growth rate or kill contaminating microorganisms without killing the recombinantly engineered cells. Also provided are methods for the production of a fermentation product using the recombinantly engineered cells.
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7.发明申请METHODS FOR PRODUCING AUTHIGENIC ROCK MINERAL FOR ALTERING ROCK HYDROLOGY 有权用于生产用于改变岩石水文学的矿物岩石矿石的方法公开(公告)号：US20140251622A1
公开(公告)日：2014-09-11
申请号：US14353267
申请日：2012-10-24
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： John D. Coates
Abstract: The present disclosure relates to methods of reversibly altering the rock hydrology in systems, such as oil reservoirs, by inducing authigenic mineral-precipitating bacteria to produce authigenic rock mineral.
Abstract translation: 本公开涉及通过诱导自生矿物沉淀细菌产生自生岩石矿物来可逆地改变诸如油藏的系统中的岩石水文学的方法。
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