公开(公告)号：US12209245B2

公开(公告)日：2025-01-28

申请号：US16671036

申请日：2019-10-31

Applicant: The Regents of the University of California

Inventor： Ethan Mirsky ,  Karsten Temme ,  Christopher A. Voigt ,  Dehua Zhao

IPC: C12N15/63 ,  C07K14/255 ,  C07K14/26 ,  C12N9/02 ,  C12N15/52 ,  C12N15/67 ,  C12N15/74 ,  G16B25/00 ,  G16B30/00 ,  G16B30/10 ,  G16B30/20

Abstract: Methods for making synthetic gene clusters are described.

公开(公告)号：US20180073028A1

公开(公告)日：2018-03-15

申请号：US15706353

申请日：2017-09-15

Applicant: The Regents of the University of California

Inventor： Ethan Mirsky ,  Karsten Temme ,  Christopher A. Voigt ,  Dehua Zhao

IPC: C12N15/63 ,  C12N9/02 ,  G06F19/22 ,  G06F19/20 ,  C07K14/26

Abstract: Methods for making synthetic gene clusters are described.

公开(公告)号：US20200048227A1

公开(公告)日：2020-02-13

申请号：US16462460

申请日：2017-11-15

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventor： Michael A. Fischbach ,  Chun-Jun Guo ,  Christopher A. Voigt ,  Fang-Yuan Chang ,  Jon Clardy ,  Thomas Wyche

IPC: C07D403/14 ,  C07C237/20 ,  C07D403/12 ,  C07C323/60 ,  C07D241/18 ,  C07D241/12 ,  C07D403/06

Abstract: Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer.

公开(公告)号：US20170152519A1

公开(公告)日：2017-06-01

申请号：US15288916

申请日：2016-10-07

Applicant: The Regents of the University of California

Inventor： Ethan Mirsky ,  Karsten Temme ,  Christopher A. Voigt ,  Dehua Zhao

IPC: C12N15/63 ,  C12N9/02 ,  C07K14/26 ,  G06F19/20 ,  G06F19/22

CPC classification number: C12N15/635 ,  C07K14/255 ,  C07K14/26 ,  C12N9/0095 ,  C12N15/52 ,  C12N15/63 ,  C12N15/67 ,  C12N15/74 ,  C12Y118/06001 ,  G06F19/20 ,  G06F19/22

Abstract: Methods for making synthetic gene clusters are described.

公开(公告)号：US10662432B2

公开(公告)日：2020-05-26

申请号：US15706353

申请日：2017-09-15

Applicant: The Regents of the University of California

Inventor： Ethan Mirsky ,  Karsten Temme ,  Christopher A. Voigt ,  Dehua Zhao

IPC: C12N15/63 ,  C12N15/00 ,  C12N1/20 ,  G16B25/00 ,  G16B30/00 ,  C07K14/255 ,  C07K14/26 ,  C12N15/52 ,  C12N15/67 ,  C12N15/74 ,  C12N9/02

Abstract: Methods for making synthetic gene clusters are described.

公开(公告)号：US09957509B2

公开(公告)日：2018-05-01

申请号：US15288916

申请日：2016-10-07

Applicant: The Regents of the University of California

Inventor： Ethan Mirsky ,  Karsten Temme ,  Christopher A. Voigt ,  Dehua Zhao

IPC: C12N15/63 ,  G06F19/22 ,  G06F19/20 ,  C07K14/26 ,  C12N9/02

CPC classification number: C12N15/635 ,  C07K14/255 ,  C07K14/26 ,  C12N9/0095 ,  C12N15/52 ,  C12N15/63 ,  C12N15/67 ,  C12N15/74 ,  C12Y118/06001 ,  G06F19/20 ,  G06F19/22

Abstract: Methods for making synthetic gene clusters are described.

公开(公告)号：US11124498B2

公开(公告)日：2021-09-21

申请号：US16462460

申请日：2017-11-15

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY ,  PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventor： Michael A. Fischbach ,  Chun-Jun Guo ,  Christopher A. Voigt ,  Fang-Yuan Chang ,  Jon Clardy ,  Thomas Wyche

IPC: C07D403/14 ,  C07C237/20 ,  C07D403/12 ,  C07C323/60 ,  C07D241/18 ,  C07D241/12 ,  C07D403/06

Abstract: Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer.