公开(公告)号：US12022832B2

公开(公告)日：2024-07-02

申请号：US17275849

申请日：2019-09-10

Applicant: The Governing Council of The University of Toronto

Inventor： Peter John Roy ,  Sean Harrington ,  Andrew Burns ,  Jacob Edward Pyche ,  Genna M. Luciani ,  Jessica Knox ,  Mark Lautens ,  Ken Loon Choo

IPC: A01N43/40 ,  A01N43/54 ,  A01N43/60 ,  A01P5/00 ,  A61K31/44 ,  A61K31/4418 ,  A61K31/445 ,  A61K31/495 ,  A61K31/505 ,  A61P33/10

CPC classification number: A01N43/40 ,  A01N43/54 ,  A01N43/60 ,  A01P5/00 ,  A61K31/44 ,  A61K31/4418 ,  A61K31/445 ,  A61K31/495 ,  A61K31/505 ,  A61P33/10

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula (III) as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection.

公开(公告)号：US11517568B2

公开(公告)日：2022-12-06

申请号：US17018158

申请日：2020-09-11

Applicant: The Governing Council of The University of Toronto

Inventor： Peter Roy ,  Sean Harrington ,  Jacob Pyche ,  Andrew Burns ,  Rachel Ross ,  Mark Lautens

IPC: A61K31/495 ,  A01N43/60 ,  A61P33/10 ,  A61P31/00 ,  A61K9/20 ,  A23K20/116 ,  A61K9/00 ,  A23K50/70

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula (I) and/or (II) as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection:

公开(公告)号：US20240389588A1

公开(公告)日：2024-11-28

申请号：US18665989

申请日：2024-05-16

Applicant: The Governing Council of the University of Toronto

Inventor： Peter John Roy ,  Sean Harrington ,  Andrew Burns ,  Jacob Edward Pyche ,  Genna M. Luciani ,  Jessica Knox ,  Mark Lautens ,  Ken Loon Choo

IPC: A01N43/40 ,  A01N43/54 ,  A01N43/60 ,  A01P5/00 ,  A61K31/44 ,  A61K31/4418 ,  A61K31/445 ,  A61K31/495 ,  A61K31/505 ,  A61P33/10

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula (III) as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection.

公开(公告)号：US20240109914A1

公开(公告)日：2024-04-04

申请号：US18271522

申请日：2022-01-13

Applicant: The Governing Council of The University of Toronto

Inventor： Andrew Burns ,  Peter Roy ,  Rachel Baker ,  Mark Lautens

IPC: C07D513/04 ,  A01N43/90 ,  A01P5/00

CPC classification number: C07D513/04 ,  A01N43/90 ,  A01P5/00

Abstract: The present application relates to the treatment of plant nematode infections. For example, the application relates to the use of one or more compounds of Formula (I) as defined herein, or compositions comprising these compounds, for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection in a plant in need thereof. Also included are novel compounds within the scope of Formula I and compositions and uses of these compounds for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection in a plant in need thereof.

公开(公告)号：US11364234B2

公开(公告)日：2022-06-21

申请号：US16565917

申请日：2019-09-10

Applicant: The Governing Council of The University of Toronto ,  Ontario Institute for Cancer Research (OICR)

Inventor： Peter Roy ,  Sean Harrington ,  Jacob Pyche ,  Daniel Kulke ,  Genna M. Luciani ,  Andrew Burns ,  Mark Lautens ,  Rachel Ross ,  David Uehling

IPC: A61K31/495 ,  A01N43/60 ,  A61P33/10 ,  A61K31/445

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula I and/or II as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection:

公开(公告)号：US20230339874A1

公开(公告)日：2023-10-26

申请号：US18025665

申请日：2021-09-10

Applicant: The Governing Council of the University of Toronto

Inventor： Peter Roy ,  Sean Harrington ,  Jacob Pyche ,  Andrew Burns ,  Rachel Baker ,  Mark Lautens

IPC: C07D295/073 ,  A01N43/60 ,  C07D213/74 ,  A61P33/10 ,  A01P5/00

CPC classification number: C07D295/073 ,  A01N43/60 ,  C07D213/74 ,  A61P33/10 ,  A01P5/00

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V) and/or Formula (VI) as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection:

公开(公告)号：US20220354117A1

公开(公告)日：2022-11-10

申请号：US17275849

申请日：2019-09-10

Applicant: The Governing Council of The University of Toronto

Inventor： Peter John Roy ,  Sean Harrington ,  Andrew Burns ,  Jacob Edward Pyche ,  Genna M. Luciani ,  Jessica Knox ,  Mark Lautens ,  Ken Loon Choo

IPC: A01N43/40 ,  A01N43/54 ,  A61K31/44 ,  A61K31/505 ,  A61P33/10

Abstract: The present application relates to the treatment of nematode infections. For example, the application relates to the use of compounds of Formula (III) as defined herein for treatment of a nematode infection or a disease, disorder or condition arising from a nematode infection.