公开(公告)号：US20220024924A1

公开(公告)日：2022-01-27

申请号：US17297035

申请日：2019-11-27

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Nikolina Janton ,  Helena Ceric ,  Sanja Matecic Musanic ,  Natasa Mrsic ,  Lidija Lerman ,  Tina D. Momcilovic ,  Ivana Sagud ,  Alexandr Jegorov

IPC: C07D471/16 ,  C07C309/29

Abstract: The present disclosure relates to solid state forms of Lumateperone besylate and Lumateperone tosylate:R-(−)-mandelic acid, to various intermediates, to processes for their preparation and the preparation of Lumateperone or salt thereof, to pharmaceutical compositions and their use for the treatment of central nervous system disorders.