公开(公告)号：US20250034113A1

公开(公告)日：2025-01-30

申请号：US18714646

申请日：2022-12-01

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Zuzana Przeczkova ,  Adéla Bártová ,  Pavel Kolesa ,  Alexandr Jegorov ,  Jana Romanová

IPC: C07D401/12 ,  A61K31/513

Abstract: The present disclosure encompasses solid state forms of Tavapadon, processes for preparation thereof, and pharmaceutical compositions thereof.

公开(公告)号：US20240199578A1

公开(公告)日：2024-06-20

申请号：US18285699

申请日：2022-04-08

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Adéla Bártová ,  Alexandr Jegorov ,  Pavel Kolesa ,  Zuzana Trcková

IPC: C07D401/14 ,  A61K31/496

CPC classification number: C07D401/14 ,  A61K31/496

Abstract: The present disclosure encompasses solid state forms of Zavegepant, in embodiments crystalline polymorphs of Zavegepant, processes for preparation thereof, and pharmaceutical compositions thereof.

公开(公告)号：US20240010629A1

公开(公告)日：2024-01-11

申请号：US17777663

申请日：2020-12-10

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Zuzana Trcková ,  Adéla Bártová ,  Pavel Kolesa ,  Alexandr Jegorov

IPC: C07D401/12 ,  C07C55/10

CPC classification number: C07D401/12 ,  C07C55/10 ,  C07B2200/13

Abstract: The present disclosure encompasses Lemborexant: succinic acid, a solid state form thereof, processes for preparation thereof, and pharmaceutical compositions thereof.

公开(公告)号：US20230373998A1

公开(公告)日：2023-11-23

申请号：US18030785

申请日：2021-10-12

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Zuzana Przeczkova ,  Adéla Bártová ,  Pavel Kolesa ,  Alexandr Jegorov

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: The present disclosure encompasses solid state forms of Lorecivivint, in embodiments crystalline polymorphs of Lorecivivint, processes for preparation thereof, and pharmaceutical compositions thereof.

公开(公告)号：US20220024924A1

公开(公告)日：2022-01-27

申请号：US17297035

申请日：2019-11-27

Applicant: TEVA CZECH INDUSTRIES S.R.O

Inventor： Nikolina Janton ,  Helena Ceric ,  Sanja Matecic Musanic ,  Natasa Mrsic ,  Lidija Lerman ,  Tina D. Momcilovic ,  Ivana Sagud ,  Alexandr Jegorov

IPC: C07D471/16 ,  C07C309/29

Abstract: The present disclosure relates to solid state forms of Lumateperone besylate and Lumateperone tosylate:R-(−)-mandelic acid, to various intermediates, to processes for their preparation and the preparation of Lumateperone or salt thereof, to pharmaceutical compositions and their use for the treatment of central nervous system disorders.