公开(公告)号：US20230241610A1

公开(公告)日：2023-08-03

申请号：US17589591

申请日：2022-01-31

Applicant: TDK U.S.A. Corporation

Inventor： Manish Giri ,  Rakesh Sethi ,  Vadim Piskun

IPC: B01L3/00

CPC classification number: B01L3/502761 ,  B01L2200/027 ,  B01L2200/0652 ,  B01L2300/12 ,  B01L2400/0415

Abstract: A microfluidic device and a method for flow control of cells or particles in a microfluidic channel are disclosed. The microfluidic device may include a substrate with a microfluidic channel having at least one outlet; a first array of piezoelectric actuators located adjacent to the outlet for ejecting a portion of a fluid in the microfluidic channel; and one or more pairs of electrodes for charging particles (in the fluid) flowing through the microfluidic channel so that the particles can be manipulated with an electrical field.

公开(公告)号：US20230011704A1

公开(公告)日：2023-01-12

申请号：US17367818

申请日：2021-07-06

Applicant: TDK U.S.A. Corporation

Inventor： Vadim Piskun ,  Rakesh Sethi

IPC: H02N2/18 ,  H02J3/38 ,  H02M3/157 ,  H02M1/00

Abstract: A method includes converting an electrical output provided by an energy generator with a first voltage converter; and, subsequent to converting the electrical output provided by the energy generator with the first voltage converter, activating, with a microprocessor, a second voltage converter for converting the electrical output provided by the energy generator with the second voltage converter. An electrical device with a microprocessor for selecting one of two or more voltage converters is also described.

公开(公告)号：US20230241605A1

公开(公告)日：2023-08-03

申请号：US17970569

申请日：2022-10-21

Applicant: TDK U.S.A. Corporation

Inventor： Manish Giri ,  Rakesh Sethi ,  Vadim Piskun

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/502761 ,  B01L2300/0816 ,  B01L2400/0475 ,  B01L2300/0645 ,  B01L2300/0861

Abstract: A microfluidic device and a method for flow control of cells or particles in a microfluidic channel are disclosed. The microfluidic device may include a substrate with a microfluidic channel having at least one outlet; a first array of piezoelectric actuators located adjacent to the outlet for ejecting a portion of a fluid in the microfluidic channel; and one or more pairs of electrodes for charging particles (in the fluid) flowing through the microfluidic channel so that the particles can be manipulated with an electrical field.

公开(公告)号：US20240335837A1

公开(公告)日：2024-10-10

申请号：US18605476

申请日：2024-03-14

Applicant: TDK U.S.A. Corporation

Inventor： Manish Giri ,  Rakesh Sethi ,  Vadim Piskun

IPC: B01L3/00

CPC classification number: B01L3/502761 ,  B01L2200/0647 ,  B01L2300/0663 ,  B01L2300/0864 ,  B01L2400/0436 ,  B01L2400/0496

Abstract: A microfluidic device and a method for dissociating and manipulating cells or particles in a microfluidic channel are disclosed. The microfluidic device includes an inlet, an outlet, and a microfluidic channel arranged on a substrate between the inlet and the outlet. The microfluidic device includes a first set of piezoelectric actuators arranged adjacent to the inlet channel and configured to dissociate particles of a fluidic sample in the microfluidic channel. The microfluidic device includes a second set of piezoelectric actuators arranged between the inlet channel and the outlet channel and configured to manipulate the particles of the fluidic sample as the particles move through the microfluidic channel. The microfluidic device includes a third set of piezoelectric actuators arranged above the outlet channel, adjacent to the outlet, and configured to eject a portion of the fluidic sample out of the microfluidic channel via the outlet.