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公开(公告)号：US3607648A
公开(公告)日：1971-09-21
申请号：US3607648D
申请日：1969-01-29
发明人： YONEDA MASAHIKO , SASJIMA KEN-ICHI
CPC分类号： C12P19/02 , Y10S435/839
摘要： D-ribose is produced by culturing a D-ribose-producing microorganism of the genus Bacillus, said micro-organism requiring Ltyrosine, L-tryptophan and L-phenylalanine in a proper culture medium. The accumulated D-ribose is subsequently recovered from the medium.
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公开(公告)号：US3926729A
公开(公告)日：1975-12-16
申请号：US34984973
申请日：1973-04-10
CPC分类号： C12P35/06 , Y10S435/926
摘要： Deacetylcephalosporin C is produced by cultivating a microorganism which belongs to genus Cephalosporium and is capable of producing deacetylcephalosporin C and accumulating it in the culture broth. The accumulated deacetylcephalosporin C can easily be recovered from the culture broth.
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公开(公告)号：US3919046A
公开(公告)日：1975-11-11
申请号：US41556173
申请日：1973-11-14
发明人： SASAJIMA KEN-ICHI , YONEDA MASAHIKO
CPC分类号： C12P19/02 , Y10S435/832 , Y10S435/839
摘要： D-ribose is produced by cultivating a strain belonging to the genus Bacillus whose transketolase activity is nil to cause said strain to elaborate and accumulate a large amount of D-ribose. The thus accumulated D-ribose can be recovered in a good yield.
摘要翻译： 通过培养属于芽孢杆菌属的杆菌属的菌株产生D-核糖，其转酮酶活性为零，以使所述菌株精制并积累大量的D-核糖。 可以以良好的收率回收这样积累的D-核糖。
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公开(公告)号：US3660564A
公开(公告)日：1972-05-02
申请号：US3660564D
申请日：1969-12-23
发明人： YONEDA MASAHIKO , YAOI HIDEAKI , KIDA MAKOTO , MATSUDA SHINOBU , SHIRAFUJI HIDEO
CPC分类号： C07H21/00 , Y10S435/811 , Y10S435/822 , Y10S514/889
摘要： A METHOD FOR INDUCING INTERFERON FORMATION IN VIVO AND IN VITRO. TO A HOST OR A TISSUE CULTURE IS ADMINISTERED A DOUBLE-STRANDED COMPLEX OF (A) HETEROPOLYNUCLEOTIDE ESSENTIALLY CONSISTING OF INOSINIC ACID AND GUANYLIC ACID AS ITS NUCLEOTIDE UNITS AND (B) HOMOPOLYNUCLEOTIDE ESSENTIALLY CONSISTING OF CYTIDYLIC ACID AS ITS NUCLEOTIDE UNIT, THE HETEROPOLYNUCLEOTIDE (A) BEING OF A SEDIMENTATION CONSTANT FALLING WITHIN THE RANGE FROM ABOUT 2S TO ABOUT 15S IN TERMS OF SVEDBERG UNITS, AND THE RATIO OF THE AVERAGE NUMBER OF THE INOSINIC ACID UNITS THEREIN BEING FROM ABOUT 0.7 TO ABOUT 20 PER UNIT OF THE GUANYLIC ACID.
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6.发明授权
公开(公告)号：US3907764A
公开(公告)日：1975-09-23
申请号：US34912973
申请日：1973-04-09
CPC分类号： C07K14/8142 , A61K38/55 , C12P1/04 , C12P21/02 , Y10S435/886
摘要： Protease inhibitor which has strong inhibitory action against pepsin and other acid protease is produced by a microorganism of the genus Streptomyces. The protease inhibitor is recovered from the culture medium and purified and the purified protease inhibitor is used as an effective drug for the prevention and cure of hyperpepsia, hyperpepsinia and gastric and duodenal ulcers.
摘要翻译： 对胃蛋白酶和其他酸性蛋白酶具有强抑制作用的蛋白酶抑制剂由链霉菌属的微生物产生。 从培养基中回收蛋白酶抑制剂，纯化，纯化的蛋白酶抑制剂用作预防和治愈胃肠和十二指肠溃疡的有效药物。
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公开(公告)号：US3616207A
公开(公告)日：1971-10-26
申请号：US3616207D
申请日：1966-12-27
发明人： YONEDA MASAHIKO , IMADA AKIRA
CPC分类号： C12P19/32 , C12P19/40 , Y10S435/836
摘要： 5''-INOSINIC ACID AND/OR INOSINE ARE(IS) PRODUCED BY INCUBATING ADENINE-, AMINO ACID- OR/AND VITAMIN- DOUBLE OR TRIPLE REQUIRING MUTANTS DERIVED FROM Bacillus licheniformis, in a culture medium containing an adenine source and an amino acid source and/or a vitamin source.
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公开(公告)号：US3616206A
公开(公告)日：1971-10-26
申请号：US3616206D
申请日：1966-09-02
发明人： NOGAMI IKUO , KATSUMATA MICHIO , IMADA AKIRA , KIDA MAKOTO , YONEDA MASAHIKO
CPC分类号： C12P19/40 , Y10S435/832
摘要： Method for the production of inosine which comprises inoculating an adenine and amino acid-double requiring mutant such as Bacillus pumulis Gottheil No. 3218 (ATCC No. 21005), onto a culture medium containing adenine source and amino acid source, incubating the culture medium until inosine is accumulated and recovering inosine from the culture medium.
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公开(公告)号：US3607649A
公开(公告)日：1971-09-21
申请号：US3607649D
申请日：1969-06-11
发明人： YONEDA MASAHIKO , KIDA MAKOTO , HEMMI TELUJI , NOGAMI IKUO , IMADA AKIRA , TAKEUCHI YUICHI , OHMURA EINOSUKE
CPC分类号： C12P19/32 , C12P19/40 , Y10S435/832 , Y10S435/837 , Y10S435/84
摘要： 5''-GUANYLIC ACID, GUANOSINE OR A MIXTURE THEREOF PRODUCED BY CULTURING A MUTANT OF Bacillus pumilus Gottheil, Bacillus megaterium de Bary or Brevibacterium ammoniagenes Breed which requires both (1) adenine and (2) an amino acid and/or a watersoluble vitamin.
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