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公开(公告)号：US20230165260A1
公开(公告)日：2023-06-01
申请号：US18103082
申请日：2023-01-30
发明人： Ching-Hong Yang , Xiangyang Liu
IPC分类号： A01N63/27 , C12N1/20 , C07D213/90 , C07D491/048 , A61K35/74
CPC分类号： A01N63/27 , C12N1/20 , C07D213/90 , C07D491/048 , A61K35/74 , C07B2200/13
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to compounds having Formulas (I), (II), and (III):
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公开(公告)号：US11582973B2
公开(公告)日：2023-02-21
申请号：US17063540
申请日：2020-10-05
发明人： Ching-Hong Yang , Xiangyang Liu
IPC分类号： A01N63/27 , C12N1/20 , C07D213/90 , C07D491/048 , A61K35/74
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to compounds having Formulas (I), (II), and (III):
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3.发明公开公开(公告)号：US20230309565A1
公开(公告)日：2023-10-05
申请号：US18120799
申请日：2023-03-13
发明人： Ching-Hong Yang , Jian Huang
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, to inhibit the growth of a variety of microbial species for bacterial pathogens that cause citrus Huanglongbing (citrus greening disease), Zebra chip (ZC) disease of potato, tomato, and other plants of the family Solanaceae and plants of the family Apiaceae and Umbelliferae. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to a Pseudomonas bacterial metabolite as Formula (I):
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4.发明申请公开(公告)号：US20220232834A1
公开(公告)日：2022-07-28
申请号：US17587166
申请日：2022-01-28
发明人： Ching-Hong Yang , Xiangyang Liu
摘要： The present disclosure concerns methods of using Pseudomonas chlororaphis subsp. aurantiaca 1214-CHY4 (Accession No. PTA-126941), the cell broth and novel metabolites produced therefrom, that can inhibit the growth of a variety of microbial species for a variety of crops.
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公开(公告)号：US20220104500A1
公开(公告)日：2022-04-07
申请号：US17063540
申请日：2020-10-05
发明人： Ching-Hong Yang , Xiangyang Liu
IPC分类号： A01N63/27 , C12N1/20 , A61K35/74 , C07D213/90 , C07D491/048
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to compounds having Formulas (I), (II), and (III):
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公开(公告)号：US20220104487A1
公开(公告)日：2022-04-07
申请号：US17493594
申请日：2021-10-04
发明人： Ching-Hong Yang , Jian Huang
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops and fungal pathogens. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to compounds having Formulas (I), (II), and (III):
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7.发明公开公开(公告)号：US20230285472A1
公开(公告)日：2023-09-14
申请号：US18120528
申请日：2023-03-13
发明人： Ching-Hong Yang , Jian Huang
摘要： The present invention relates to an antimicrobial composition and probiotics against bacterial and fungal pathogens of fish. In particular, the invention pertains to a novel strain of the bacterial species Pseudomonas chlororaphis subsp. aurantiaca 1214-CHY4 (ATCC accession number PTA-126941), the cells, cell broth, and novel metabolites produced from the bacterial strain that can inhibit the growth of a variety of fish pathogens.
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公开(公告)号：US11590115B2
公开(公告)日：2023-02-28
申请号：US17494068
申请日：2021-10-05
发明人： Ching-Hong Yang , Jian Huang
IPC分类号： A61K31/04 , A61K31/4412 , A61P31/04 , A61K35/74
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of fish pathogens. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to a compound having Formula (I):
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公开(公告)号：US20220105080A1
公开(公告)日：2022-04-07
申请号：US17494068
申请日：2021-10-05
发明人： Ching-Hong Yang , Jian Huang
IPC分类号： A61K31/4412 , A61K35/74 , A61P31/04
摘要： The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of fish pathogens. The methods include use of novel, potent antimicrobial metabolites produced from the strains corresponding to a compound having Formula (I):
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公开(公告)号：US20180235210A1
公开(公告)日：2018-08-23
申请号：US15902040
申请日：2018-02-22
发明人： Quan Zeng , Ching-Hong Yang
IPC分类号： A01N25/10 , A01N63/00 , A01N57/12 , C12N15/113 , C07K19/00 , C07K7/06 , C07K7/08 , C07K14/00
CPC分类号： A01N25/10 , A01N57/12 , A01N63/00 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/27 , C07K19/00 , C07K2319/10 , C12N15/113 , C12N15/1137 , C12N2310/11 , C12N2310/3181 , C12N2310/3513 , A01N25/30
摘要： The invention generally relates to antisense compositions targeting Erwinia species and methods of using the same. More specifically, the invention relates in part to compositions including a cell penetrating peptide (CPP) linked to an antisense polynucleotide complementary to a target sequence in an RNA expressed from an essential gene in an Erwinia species and methods of using such compositions to inhibit the growth of an Erwinia species on a plant.
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